6XTP
Crystal structure reveals non-coordinative binding of O2 to the copper center of the formylglycine-generating enzyme - FGE:Cu:S:O2-1a complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0018158 | biological_process | protein oxidation |
| A | 0043687 | biological_process | post-translational protein modification |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0120147 | molecular_function | formylglycine-generating oxidase activity |
| A | 1903136 | molecular_function | cuprous ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CU1 A 401 |
| Chain | Residue |
| A | TRP228 |
| A | CYS269 |
| A | CYS274 |
| A | OXY404 |
| C | CYS7 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| A | GLY264 |
| A | GLY265 |
| A | ASN222 |
| A | VAL223 |
| A | GLY225 |
| A | VAL227 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | ASN188 |
| A | ILE189 |
| A | ASP202 |
| A | TYR204 |
| A | HOH520 |
| A | HOH543 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue OXY A 404 |
| Chain | Residue |
| A | TRP228 |
| A | SER266 |
| A | CYS269 |
| A | HIS293 |
| A | CU1401 |
| A | HOH565 |
| C | CYS7 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SOA C 101 |
| Chain | Residue |
| A | ILE249 |
| A | TYR273 |
| C | ALA2 |
| C | THR3 |
| C | HOH204 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28544744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5NXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5NYY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27862795","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28544744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5NXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5NYY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
