6XT8

Crystal structure of haloalkane dehalogenase variant DhaA115 domain-swapped dimer type-2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0009636	biological_process	response to toxic substance
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0018786	molecular_function	haloalkane dehalogenase activity
B	0003824	molecular_function	catalytic activity
B	0009636	biological_process	response to toxic substance
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0018786	molecular_function	haloalkane dehalogenase activity
C	0003824	molecular_function	catalytic activity
C	0009636	biological_process	response to toxic substance
C	0016020	cellular_component	membrane
C	0016787	molecular_function	hydrolase activity
C	0018786	molecular_function	haloalkane dehalogenase activity
D	0003824	molecular_function	catalytic activity
D	0009636	biological_process	response to toxic substance
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0018786	molecular_function	haloalkane dehalogenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CL A 301

Chain	Residue
A	ASN41
A	TRP107
A	HOH407
B	PHE205
B	PRO206

---

site_id	AC2
Number of Residues	8
Details	binding site for residue GOL A 302

Chain	Residue
A	ARG122
A	HOH405
A	HOH453
A	HOH473
A	ASP89
A	GLU93
A	ARG118
A	ASN119

---

site_id	AC3
Number of Residues	8
Details	binding site for residue GOL A 303

Chain	Residue
A	TRP138
A	ARG153
A	HOH401
A	HOH518
A	HOH532
A	HOH590
B	ILE211
B	GLU214

---

site_id	AC4
Number of Residues	4
Details	binding site for residue PG4 A 304

Chain	Residue
A	THR242
A	PHE266
A	GLY268
A	PRO269

---

site_id	AC5
Number of Residues	7
Details	binding site for residue EDO A 305

Chain	Residue
A	GLY213
A	TRP219
A	HOH411
A	HOH440
B	GLY5
B	THR6
B	GLY7

---

site_id	AC6
Number of Residues	4
Details	binding site for residue CL B 301

Chain	Residue
A	PHE205
A	PRO206
B	ASN41
B	TRP107

---

site_id	AC7
Number of Residues	5
Details	binding site for residue GOL B 302

Chain	Residue
B	ASP89
B	ARG118
B	ASN119
B	HOH428
B	HOH543

---

site_id	AC8
Number of Residues	9
Details	binding site for residue GOL B 303

Chain	Residue
B	PHE8
B	SER44
B	GLY70
B	LYS71
B	HIS188
B	GLU191
B	HOH404
B	HOH406
B	HOH419

---

site_id	AC9
Number of Residues	6
Details	binding site for residue CL C 301

Chain	Residue
C	ASN41
C	TRP107
C	PHE168
C	HOH409
D	PHE205
D	PRO206

---

site_id	AD1
Number of Residues	6
Details	binding site for residue GOL C 302

Chain	Residue
C	GLY5
C	THR6
C	GLY7
C	HOH422
D	ASN227
D	GLN231

---

site_id	AD2
Number of Residues	7
Details	binding site for residue GOL C 303

Chain	Residue
C	PHE8
C	GLY70
C	LYS71
C	HIS188
C	GLU191
C	HOH404
C	HOH407

---

site_id	AD3
Number of Residues	7
Details	binding site for residue GOL C 304

Chain	Residue
C	ASP89
C	GLU93
C	TRP115
C	ARG118
C	ASN119
C	ARG122
C	HOH457

---

site_id	AD4
Number of Residues	2
Details	binding site for residue EDO C 305

Chain	Residue
C	PHE144
C	HOH410

---

site_id	AD5
Number of Residues	5
Details	binding site for residue CL C 306

Chain	Residue
C	PHE205
C	PRO206
D	ASN41
D	TRP107
D	HOH387

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	496
Details	Domain: {"description":"AB hydrolase-1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---