Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004775 | molecular_function | succinate-CoA ligase (ADP-forming) activity |
| B | 0004776 | molecular_function | succinate-CoA ligase (GDP-forming) activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0006104 | biological_process | succinyl-CoA metabolic process |
| B | 0016874 | molecular_function | ligase activity |
| B | 0042709 | cellular_component | succinate-CoA ligase complex |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | binding site for residue DCA A 401 |
| Chain | Residue |
| A | GLY22 |
| A | VAL80 |
| A | PRO81 |
| A | PRO82 |
| A | ILE103 |
| A | THR104 |
| A | GLU105 |
| A | ASN131 |
| A | CYS132 |
| A | ILE145 |
| A | HOH505 |
| A | THR24 |
| A | HOH518 |
| A | HOH522 |
| A | HOH525 |
| A | HOH535 |
| A | HOH542 |
| A | HOH552 |
| A | HOH555 |
| A | HOH567 |
| A | HOH576 |
| A | HOH633 |
| A | GLY25 |
| A | HOH639 |
| A | HOH647 |
| A | HOH648 |
| A | HOH658 |
| A | HOH716 |
| B | GLY298 |
| B | SIN401 |
| A | LYS26 |
| A | GLN27 |
| A | THR46 |
| A | PRO48 |
| A | LYS50 |
| A | TYR79 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue SIN A 402 |
| Chain | Residue |
| A | ARG256 |
| A | ALA265 |
| A | GLY266 |
| A | HOH502 |
| A | HOH570 |
| A | HOH582 |
| A | HOH606 |
| B | THR201 |
| B | ASN224 |
| B | HOH725 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | GLY139 |
| A | HIS151 |
| A | LYS152 |
| A | LYS153 |
| A | HOH506 |
| A | HOH508 |
| B | GLU74 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | LEU249 |
| A | THR250 |
| B | PHE284 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | SER286 |
| A | MET287 |
| A | SER288 |
| A | GLN291 |
| A | THR295 |
| A | HOH720 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residue PO4 A 406 |
| Chain | Residue |
| A | SER162 |
| A | GLY163 |
| A | THR164 |
| A | HIS259 |
| A | HOH531 |
| A | HOH600 |
| A | HOH610 |
| B | GLY272 |
| B | ALA273 |
| B | GLY274 |
| B | SIN401 |
| B | MG405 |
| B | HOH555 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | binding site for residue SIN B 401 |
| Chain | Residue |
| A | ILE145 |
| A | GLY163 |
| A | TYR167 |
| A | DCA401 |
| A | PO4406 |
| A | HOH542 |
| A | HOH610 |
| B | ASN271 |
| B | GLY328 |
| B | ILE329 |
| B | VAL330 |
| B | MG405 |
| B | HOH555 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| B | ASP122 |
| B | ARG123 |
| B | LYS153 |
| B | HOH612 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| B | ASN29 |
| B | GLY77 |
| B | GLN78 |
| B | HOH609 |
| B | HOH620 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | GLN233 |
| B | LYS234 |
| B | ASP235 |
| B | HOH728 |
| B | PHE231 |
| B | ARG232 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 405 |
| Chain | Residue |
| A | PO4406 |
| A | HOH542 |
| A | HOH600 |
| A | HOH610 |
| B | SIN401 |
| B | HOH555 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 406 |
| Chain | Residue |
| A | HOH826 |
| B | HOH576 |
| B | HOH580 |
| B | HOH618 |
| B | HOH627 |
| B | HOH725 |
Functional Information from PROSITE/UniProt
| site_id | PS00399 |
| Number of Residues | 14 |
| Details | SUCCINYL_COA_LIG_2 ATP-citrate lyase / succinyl-CoA ligases family active site. GltAppgr...RMGHAG |
| Chain | Residue | Details |
| A | GLY248-GLY261 | |
| site_id | PS01216 |
| Number of Residues | 30 |
| Details | SUCCINYL_COA_LIG_1 ATP-citrate lyase / succinyl-CoA ligases family signature 1. SRSGTLTyEavhqttqvglGqslcVGIGGD |
| Chain | Residue | Details |
| A | SER160-ASP189 | |
| site_id | PS01217 |
| Number of Residues | 26 |
| Details | SUCCINYL_COA_LIG_3 ATP-citrate lyase / succinyl-CoA ligases family signature 3. GnIacFvNGAGLAmatcDiIflngGK |
| Chain | Residue | Details |
| B | GLY264-LYS289 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | GLN20 | |
| B | GLY53 | |
| B | LEU109 | |
| Chain | Residue | Details |
| B | ASN206 | |
| B | ASP220 | |
| A | ILE103 | |
| Chain | Residue | Details |
| B | ASN271 | |
| B | GLY328 | |
| Chain | Residue | Details |
| B | GLU42 | |
| B | ASP110 | |
| Chain | Residue | Details |
| B | LYS36 | |
| B | LYS95 | |
| B | LYS102 | |
| B | LYS163 | |
| B | LYS234 | |
| B | LYS310 | |
| B | LYS349 | |
| B | LYS386 | |
| Chain | Residue | Details |
| B | LYS41 | |
| B | LYS301 | |
| Chain | Residue | Details |
| B | SER124 | |
| Chain | Residue | Details |
| B | LYS190 | |
| B | LYS254 | |
