Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0004775 | molecular_function | succinate-CoA ligase (ADP-forming) activity |
B | 0004776 | molecular_function | succinate-CoA ligase (GDP-forming) activity |
B | 0005515 | molecular_function | protein binding |
B | 0005524 | molecular_function | ATP binding |
B | 0005525 | molecular_function | GTP binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005739 | cellular_component | mitochondrion |
B | 0006099 | biological_process | tricarboxylic acid cycle |
B | 0006104 | biological_process | succinyl-CoA metabolic process |
B | 0016874 | molecular_function | ligase activity |
B | 0042709 | cellular_component | succinate-CoA ligase complex |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 36 |
Details | binding site for residue DCA A 401 |
Chain | Residue |
A | GLY22 |
A | VAL80 |
A | PRO81 |
A | PRO82 |
A | ILE103 |
A | THR104 |
A | GLU105 |
A | ASN131 |
A | CYS132 |
A | ILE145 |
A | HOH505 |
A | THR24 |
A | HOH518 |
A | HOH522 |
A | HOH525 |
A | HOH535 |
A | HOH542 |
A | HOH552 |
A | HOH555 |
A | HOH567 |
A | HOH576 |
A | HOH633 |
A | GLY25 |
A | HOH639 |
A | HOH647 |
A | HOH648 |
A | HOH658 |
A | HOH716 |
B | GLY298 |
B | SIN401 |
A | LYS26 |
A | GLN27 |
A | THR46 |
A | PRO48 |
A | LYS50 |
A | TYR79 |
site_id | AC2 |
Number of Residues | 10 |
Details | binding site for residue SIN A 402 |
Chain | Residue |
A | ARG256 |
A | ALA265 |
A | GLY266 |
A | HOH502 |
A | HOH570 |
A | HOH582 |
A | HOH606 |
B | THR201 |
B | ASN224 |
B | HOH725 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue GOL A 403 |
Chain | Residue |
A | GLY139 |
A | HIS151 |
A | LYS152 |
A | LYS153 |
A | HOH506 |
A | HOH508 |
B | GLU74 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue GOL A 404 |
Chain | Residue |
A | LEU249 |
A | THR250 |
B | PHE284 |
site_id | AC5 |
Number of Residues | 6 |
Details | binding site for residue EDO A 405 |
Chain | Residue |
A | SER286 |
A | MET287 |
A | SER288 |
A | GLN291 |
A | THR295 |
A | HOH720 |
site_id | AC6 |
Number of Residues | 13 |
Details | binding site for residue PO4 A 406 |
Chain | Residue |
A | SER162 |
A | GLY163 |
A | THR164 |
A | HIS259 |
A | HOH531 |
A | HOH600 |
A | HOH610 |
B | GLY272 |
B | ALA273 |
B | GLY274 |
B | SIN401 |
B | MG405 |
B | HOH555 |
site_id | AC7 |
Number of Residues | 13 |
Details | binding site for residue SIN B 401 |
Chain | Residue |
A | ILE145 |
A | GLY163 |
A | TYR167 |
A | DCA401 |
A | PO4406 |
A | HOH542 |
A | HOH610 |
B | ASN271 |
B | GLY328 |
B | ILE329 |
B | VAL330 |
B | MG405 |
B | HOH555 |
site_id | AC8 |
Number of Residues | 4 |
Details | binding site for residue GOL B 402 |
Chain | Residue |
B | ASP122 |
B | ARG123 |
B | LYS153 |
B | HOH612 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue GOL B 403 |
Chain | Residue |
B | ASN29 |
B | GLY77 |
B | GLN78 |
B | HOH609 |
B | HOH620 |
site_id | AD1 |
Number of Residues | 6 |
Details | binding site for residue EDO B 404 |
Chain | Residue |
B | GLN233 |
B | LYS234 |
B | ASP235 |
B | HOH728 |
B | PHE231 |
B | ARG232 |
site_id | AD2 |
Number of Residues | 6 |
Details | binding site for residue MG B 405 |
Chain | Residue |
A | PO4406 |
A | HOH542 |
A | HOH600 |
A | HOH610 |
B | SIN401 |
B | HOH555 |
site_id | AD3 |
Number of Residues | 6 |
Details | binding site for residue MG B 406 |
Chain | Residue |
A | HOH826 |
B | HOH576 |
B | HOH580 |
B | HOH618 |
B | HOH627 |
B | HOH725 |
Functional Information from PROSITE/UniProt
site_id | PS00399 |
Number of Residues | 14 |
Details | SUCCINYL_COA_LIG_2 ATP-citrate lyase / succinyl-CoA ligases family active site. GltAppgr...RMGHAG |
Chain | Residue | Details |
A | GLY248-GLY261 | |
site_id | PS01216 |
Number of Residues | 30 |
Details | SUCCINYL_COA_LIG_1 ATP-citrate lyase / succinyl-CoA ligases family signature 1. SRSGTLTyEavhqttqvglGqslcVGIGGD |
Chain | Residue | Details |
A | SER160-ASP189 | |
site_id | PS01217 |
Number of Residues | 26 |
Details | SUCCINYL_COA_LIG_3 ATP-citrate lyase / succinyl-CoA ligases family signature 3. GnIacFvNGAGLAmatcDiIflngGK |
Chain | Residue | Details |
B | GLY264-LYS289 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
B | GLN20 | |
B | GLY53 | |
B | LEU109 | |
Chain | Residue | Details |
B | ASN206 | |
B | ASP220 | |
A | ILE103 | |
Chain | Residue | Details |
B | ASN271 | |
B | GLY328 | |
Chain | Residue | Details |
B | GLU42 | |
B | ASP110 | |
Chain | Residue | Details |
B | LYS36 | |
B | LYS95 | |
B | LYS102 | |
B | LYS163 | |
B | LYS234 | |
B | LYS310 | |
B | LYS349 | |
B | LYS386 | |
Chain | Residue | Details |
B | LYS41 | |
B | LYS301 | |
Chain | Residue | Details |
B | SER124 | |
Chain | Residue | Details |
B | LYS190 | |
B | LYS254 | |