6XRS

Crystal structure of a GTP-binding protein EngA (Der homolog) from Neisseria gonorrhoeae bound to GDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000027	biological_process	ribosomal large subunit assembly
A	0005525	molecular_function	GTP binding
A	0016887	molecular_function	ATP hydrolysis activity
A	0042254	biological_process	ribosome biogenesis
A	0043022	molecular_function	ribosome binding
B	0000027	biological_process	ribosomal large subunit assembly
B	0005525	molecular_function	GTP binding
B	0016887	molecular_function	ATP hydrolysis activity
B	0042254	biological_process	ribosome biogenesis
B	0043022	molecular_function	ribosome binding
C	0000027	biological_process	ribosomal large subunit assembly
C	0005525	molecular_function	GTP binding
C	0016887	molecular_function	ATP hydrolysis activity
C	0042254	biological_process	ribosome biogenesis
C	0043022	molecular_function	ribosome binding
D	0000027	biological_process	ribosomal large subunit assembly
D	0005525	molecular_function	GTP binding
D	0016887	molecular_function	ATP hydrolysis activity
D	0042254	biological_process	ribosome biogenesis
D	0043022	molecular_function	ribosome binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue GDP A 601

Chain	Residue
A	ASN200
A	SER342
A	ALA343
A	LEU344
A	VAL201
A	GLY202
A	LYS203
A	SER204
A	THR205
A	ASN309
A	LYS310
A	ASP312

---

site_id	AC2
Number of Residues	12
Details	binding site for residue GDP B 601

Chain	Residue
B	ASN200
B	VAL201
B	GLY202
B	LYS203
B	SER204
B	THR205
B	ASN309
B	LYS310
B	ASP312
B	SER342
B	ALA343
B	LEU344

---

site_id	AC3
Number of Residues	25
Details	binding site for residue GDP B 602

Chain	Residue
B	ASN27
B	VAL28
B	GLY29
B	LYS30
B	SER31
B	THR32
B	ARG108
B	LYS135
B	GLU137
B	SER160
B	GLY161
B	ALA162
B	HOH703
B	HOH705
B	HOH706
B	HOH718
D	ASN27
D	VAL28
D	GLY29
D	LYS30
D	SER31
D	THR32
D	ARG108
D	LYS135
D	ALA162

---

site_id	AC4
Number of Residues	3
Details	binding site for residue CL B 604

Chain	Residue
B	GLY166
C	ARG215
C	GLU234

---

site_id	AC5
Number of Residues	24
Details	binding site for residue GDP C 601

Chain	Residue
A	ASN27
A	VAL28
A	GLY29
A	LYS30
A	SER31
A	THR32
A	ARG108
A	LYS135
A	GLU137
A	SER160
A	ALA162
C	ASN27
C	VAL28
C	GLY29
C	LYS30
C	SER31
C	THR32
C	ASN134
C	LYS135
C	GLU137
C	SER160
C	GLY161
C	ALA162
C	HOH703

---

site_id	AC6
Number of Residues	12
Details	binding site for residue GDP C 602

Chain	Residue
C	ASN200
C	VAL201
C	GLY202
C	LYS203
C	SER204
C	THR205
C	ASN309
C	LYS310
C	ASP312
C	SER342
C	ALA343
C	LEU344

---

site_id	AC7
Number of Residues	1
Details	binding site for residue CL C 604

Chain	Residue
C	LYS371

---

site_id	AC8
Number of Residues	2
Details	binding site for residue CL C 605

Chain	Residue
C	HIS59
C	GLU271

---

site_id	AC9
Number of Residues	13
Details	binding site for residue GDP D 601

Chain	Residue
D	ASP312
D	SER342
D	ALA343
D	LEU344
D	HOH709
D	ASN200
D	VAL201
D	GLY202
D	LYS203
D	SER204
D	THR205
D	ASN309
D	LYS310

---

site_id	AD1
Number of Residues	1
Details	binding site for residue IOD D 602

Chain	Residue
D	ARG347

---

site_id	AD2
Number of Residues	2
Details	binding site for residue CL D 603

Chain	Residue
D	LYS17
D	HIS59

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00195

Chain	Residue	Details
A	GLY24
B	GLY197
B	ASP244
B	ASN309
C	GLY24
C	ASP71
C	ASN134
C	GLY197
C	ASP244
C	ASN309
D	GLY24
A	ASP71
D	ASP71
D	ASN134
D	GLY197
D	ASP244
D	ASN309
A	ASN134
A	GLY197
A	ASP244
A	ASN309
B	GLY24
B	ASP71
B	ASN134

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