6XPW

Nucleoside Diphosphate Kinase from Aspergillus fumgiatus Af293 bound to CDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0006183	biological_process	GTP biosynthetic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009142	biological_process	nucleoside triphosphate biosynthetic process
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0006183	biological_process	GTP biosynthetic process
B	0006228	biological_process	UTP biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0009142	biological_process	nucleoside triphosphate biosynthetic process
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0006183	biological_process	GTP biosynthetic process
C	0006228	biological_process	UTP biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0009142	biological_process	nucleoside triphosphate biosynthetic process
E	0004550	molecular_function	nucleoside diphosphate kinase activity
E	0006183	biological_process	GTP biosynthetic process
E	0006228	biological_process	UTP biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
E	0009142	biological_process	nucleoside triphosphate biosynthetic process
G	0004550	molecular_function	nucleoside diphosphate kinase activity
G	0006183	biological_process	GTP biosynthetic process
G	0006228	biological_process	UTP biosynthetic process
G	0006241	biological_process	CTP biosynthetic process
G	0009142	biological_process	nucleoside triphosphate biosynthetic process
H	0004550	molecular_function	nucleoside diphosphate kinase activity
H	0006183	biological_process	GTP biosynthetic process
H	0006228	biological_process	UTP biosynthetic process
H	0006241	biological_process	CTP biosynthetic process
H	0009142	biological_process	nucleoside triphosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue PO4 A 201

Chain	Residue
A	LYS11
A	HOH449
A	THR93
A	ASN114
A	HIS117
A	HOH302
A	HOH307
A	HOH312
A	HOH393
A	HOH425

---

site_id	AC2
Number of Residues	16
Details	binding site for residue CDP B 201

Chain	Residue
B	LYS11
B	TYR51
B	PHE59
B	LEU63
B	ARG87
B	THR93
B	VAL111
B	ASN114
B	HIS117
B	HOH303
B	HOH317
B	HOH343
B	HOH397
B	HOH398
B	HOH434
E	HOH352

---

site_id	AC3
Number of Residues	8
Details	binding site for residue PO4 C 201

Chain	Residue
C	LYS11
C	THR93
C	ASN114
C	HIS117
C	HOH304
C	HOH307
C	HOH399
C	HOH414

---

site_id	AC4
Number of Residues	11
Details	binding site for residue PO4 E 201

Chain	Residue
E	LYS11
E	THR93
E	ARG104
E	ASN114
E	HIS117
E	HOH301
E	HOH302
E	HOH303
E	HOH346
E	HOH369
E	HOH447

---

site_id	AC5
Number of Residues	12
Details	binding site for residue PO4 G 201

Chain	Residue
G	LYS11
G	THR93
G	ARG104
G	ASN114
G	HIS117
G	HOH302
G	HOH309
G	HOH310
G	HOH318
G	HOH391
G	HOH394
G	HOH459

---

site_id	AC6
Number of Residues	8
Details	binding site for residue PO4 H 201

Chain	Residue
C	HOH376
H	LYS11
H	THR93
H	ASN114
H	HIS117
H	HOH305
H	HOH306
H	HOH344

---

Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NvcHGSDSV

Chain	Residue	Details
A	ASN114-VAL122

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Pros-phosphohistidine intermediate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---