6XPV

Nucleoside Diphosphate Kinase from Aspergillus fumgiatus Af293 bound to dTDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0006183	biological_process	GTP biosynthetic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009142	biological_process	nucleoside triphosphate biosynthetic process
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0006183	biological_process	GTP biosynthetic process
B	0006228	biological_process	UTP biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0009142	biological_process	nucleoside triphosphate biosynthetic process
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0006183	biological_process	GTP biosynthetic process
C	0006228	biological_process	UTP biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0009142	biological_process	nucleoside triphosphate biosynthetic process
E	0004550	molecular_function	nucleoside diphosphate kinase activity
E	0006183	biological_process	GTP biosynthetic process
E	0006228	biological_process	UTP biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
E	0009142	biological_process	nucleoside triphosphate biosynthetic process
G	0004550	molecular_function	nucleoside diphosphate kinase activity
G	0006183	biological_process	GTP biosynthetic process
G	0006228	biological_process	UTP biosynthetic process
G	0006241	biological_process	CTP biosynthetic process
G	0009142	biological_process	nucleoside triphosphate biosynthetic process
H	0004550	molecular_function	nucleoside diphosphate kinase activity
H	0006183	biological_process	GTP biosynthetic process
H	0006228	biological_process	UTP biosynthetic process
H	0006241	biological_process	CTP biosynthetic process
H	0009142	biological_process	nucleoside triphosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue TYD A 201

Chain	Residue
A	LYS11
A	PHE59
A	LEU63
A	ARG87
A	THR93
A	HOH313
A	HOH337
A	HOH368

---

site_id	AC2
Number of Residues	13
Details	binding site for residue TYD B 201

Chain	Residue
B	PHE59
B	LEU63
B	ARG87
B	THR93
B	HOH301
B	HOH304
B	HOH307
B	HOH309
B	HOH322
B	HOH339
B	HOH352
B	HOH355
B	LEU54

---

site_id	AC3
Number of Residues	12
Details	binding site for residue TYD C 201

Chain	Residue
C	LEU54
C	PHE59
C	LEU63
C	ARG87
C	THR93
C	HOH302
C	HOH305
C	HOH307
C	HOH309
C	HOH311
C	HOH335
C	HOH353

---

site_id	AC4
Number of Residues	14
Details	binding site for residue TYD E 201

Chain	Residue
E	LYS11
E	LEU54
E	PHE59
E	ARG87
E	THR93
E	HOH301
E	HOH302
E	HOH307
E	HOH315
E	HOH327
E	HOH335
E	HOH337
E	HOH348
E	HOH380

---

site_id	AC5
Number of Residues	15
Details	binding site for residue TYD G 201

Chain	Residue
G	LYS11
G	TYR51
G	LEU54
G	PHE59
G	LEU63
G	ARG87
G	THR93
G	HOH304
G	HOH307
G	HOH315
G	HOH320
G	HOH321
G	HOH331
G	HOH355
G	HOH389

---

site_id	AC6
Number of Residues	13
Details	binding site for residue TYD H 201

Chain	Residue
G	HOH312
H	LEU54
H	PHE59
H	LEU63
H	ARG87
H	THR93
H	VAL111
H	HOH301
H	HOH305
H	HOH306
H	HOH317
H	HOH324
H	HOH354

---

Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NvcHGSDSV

Chain	Residue	Details
A	ASN114-VAL122

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Pros-phosphohistidine intermediate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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