6XPT

Nucleoside Diphosphate Kinase from Aspergillus fumgiatus Af293 bound to UDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0006183	biological_process	GTP biosynthetic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009142	biological_process	nucleoside triphosphate biosynthetic process
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0006183	biological_process	GTP biosynthetic process
B	0006228	biological_process	UTP biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0009142	biological_process	nucleoside triphosphate biosynthetic process
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0006183	biological_process	GTP biosynthetic process
C	0006228	biological_process	UTP biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0009142	biological_process	nucleoside triphosphate biosynthetic process
E	0004550	molecular_function	nucleoside diphosphate kinase activity
E	0006183	biological_process	GTP biosynthetic process
E	0006228	biological_process	UTP biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
E	0009142	biological_process	nucleoside triphosphate biosynthetic process
G	0004550	molecular_function	nucleoside diphosphate kinase activity
G	0006183	biological_process	GTP biosynthetic process
G	0006228	biological_process	UTP biosynthetic process
G	0006241	biological_process	CTP biosynthetic process
G	0009142	biological_process	nucleoside triphosphate biosynthetic process
H	0004550	molecular_function	nucleoside diphosphate kinase activity
H	0006183	biological_process	GTP biosynthetic process
H	0006228	biological_process	UTP biosynthetic process
H	0006241	biological_process	CTP biosynthetic process
H	0009142	biological_process	nucleoside triphosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for residue UDP A 201

Chain	Residue
A	LYS11
A	HOH316
A	HOH321
A	HOH356
A	HOH361
A	HOH385
A	HOH388
A	TYR51
A	LEU63
A	ARG87
A	THR93
A	VAL111
A	GLY112
A	ASN114
A	HOH301

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MG B 201

Chain	Residue
B	UDP202
B	HOH611
B	HOH612
B	HOH626
B	HOH658
B	HOH725

---

site_id	AC3
Number of Residues	19
Details	binding site for residue UDP B 202

Chain	Residue
B	LYS11
B	LEU54
B	PHE59
B	LEU63
B	ARG87
B	THR93
B	VAL111
B	GLY112
B	ASN114
B	MG201
B	HOH601
B	HOH602
B	HOH611
B	HOH612
B	HOH626
B	HOH629
B	HOH646
B	HOH683
B	HOH691

---

site_id	AC4
Number of Residues	16
Details	binding site for residue UDP C 201

Chain	Residue
C	LYS11
C	LEU54
C	PHE59
C	LEU63
C	ARG87
C	THR93
C	VAL111
C	GLY112
C	ASN114
C	HOH302
C	HOH306
C	HOH311
C	HOH315
C	HOH318
C	HOH382
C	HOH394

---

site_id	AC5
Number of Residues	20
Details	binding site for residue UDP E 201

Chain	Residue
E	LYS11
E	TYR51
E	PHE59
E	LEU63
E	ARG87
E	THR93
E	VAL111
E	GLY112
E	ASN114
E	HOH302
E	HOH307
E	HOH308
E	HOH314
E	HOH328
E	HOH331
E	HOH352
E	HOH355
E	HOH374
E	HOH384
E	HOH388

---

site_id	AC6
Number of Residues	6
Details	binding site for residue MG G 201

Chain	Residue
G	UDP202
G	HOH301
G	HOH336
G	HOH352
G	HOH385
G	HOH410

---

site_id	AC7
Number of Residues	20
Details	binding site for residue UDP G 202

Chain	Residue
G	HOH348
G	HOH352
G	HOH372
G	LYS11
G	TYR51
G	LEU54
G	PHE59
G	LEU63
G	ARG87
G	THR93
G	VAL111
G	GLY112
G	ASN114
G	MG201
G	HOH301
G	HOH307
G	HOH311
G	HOH316
G	HOH324
G	HOH336

---

site_id	AC8
Number of Residues	17
Details	binding site for residue UDP H 201

Chain	Residue
H	LYS11
H	PHE59
H	LEU63
H	ARG87
H	THR93
H	VAL111
H	GLY112
H	ASN114
H	HOH1401
H	HOH1415
H	HOH1423
H	HOH1425
H	HOH1449
H	HOH1453
H	HOH1479
H	HOH1487
H	HOH1496

---

Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NvcHGSDSV

Chain	Residue	Details
A	ASN114-VAL122

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Pros-phosphohistidine intermediate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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