6XOS
CryoEM structure of human presequence protease in partial open state 1
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0005739 | cellular_component | mitochondrion |
A | 0005759 | cellular_component | mitochondrial matrix |
A | 0006508 | biological_process | proteolysis |
A | 0006626 | biological_process | protein targeting to mitochondrion |
A | 0008047 | molecular_function | enzyme activator activity |
A | 0008237 | molecular_function | metallopeptidase activity |
A | 0008270 | molecular_function | zinc ion binding |
A | 0016485 | biological_process | protein processing |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton acceptor => ECO:0000269|PubMed:16849325, ECO:0000269|PubMed:24931469 |
Chain | Residue | Details |
A | GLU107 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:Q9LJL3 |
Chain | Residue | Details |
A | GLU180 |
site_id | SWS_FT_FI3 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000269|PubMed:24931469, ECO:0007744|PDB:4L3T, ECO:0007744|PDB:4NGE |
Chain | Residue | Details |
A | HIS104 | |
A | HIS108 | |
A | GLU205 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q8K411 |
Chain | Residue | Details |
A | LYS759 | |
A | LYS884 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q8K411 |
Chain | Residue | Details |
A | LYS770 |
site_id | SWS_FT_FI6 |
Number of Residues | 2 |
Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q8K411 |
Chain | Residue | Details |
A | LYS849 | |
A | LYS946 |