6XO4

CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0019028	cellular_component	viral capsid
A	0055036	cellular_component	virion membrane
B	0005198	molecular_function	structural molecule activity
B	0019028	cellular_component	viral capsid
C	0004252	molecular_function	serine-type endopeptidase activity
C	0006508	biological_process	proteolysis
D	0004252	molecular_function	serine-type endopeptidase activity
D	0019028	cellular_component	viral capsid
D	0055036	cellular_component	virion membrane
E	0005198	molecular_function	structural molecule activity
E	0019028	cellular_component	viral capsid
F	0004252	molecular_function	serine-type endopeptidase activity
F	0006508	biological_process	proteolysis
G	0004252	molecular_function	serine-type endopeptidase activity
G	0019028	cellular_component	viral capsid
G	0055036	cellular_component	virion membrane
H	0005198	molecular_function	structural molecule activity
H	0019028	cellular_component	viral capsid
I	0004252	molecular_function	serine-type endopeptidase activity
I	0006508	biological_process	proteolysis
J	0004252	molecular_function	serine-type endopeptidase activity
J	0019028	cellular_component	viral capsid
J	0055036	cellular_component	virion membrane
K	0005198	molecular_function	structural molecule activity
K	0019028	cellular_component	viral capsid
L	0004252	molecular_function	serine-type endopeptidase activity
L	0006508	biological_process	proteolysis

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: Charge relay system => ECO:0000255|PROSITE-ProRule:PRU01027

Chain	Residue	Details
C	HIS138
L	HIS138
L	ASP160
L	SER212
C	ASP160
C	SER212
F	HIS138
F	ASP160
F	SER212
I	HIS138
I	ASP160
I	SER212

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site_id	SWS_FT_FI2
Number of Residues	8
Details	SITE: Involved in dimerization of the capsid protein => ECO:0000250|UniProtKB:Q86925

Chain	Residue	Details
C	TYR186
C	ASN219
F	TYR186
F	ASN219
I	TYR186
I	ASN219
L	TYR186
L	ASN219

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site_id	SWS_FT_FI3
Number of Residues	4
Details	SITE: Cleavage; by autolysis => ECO:0000250|UniProtKB:P03315

Chain	Residue	Details
C	TRP261
F	TRP261
I	TRP261
L	TRP261

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site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P09592

Chain	Residue	Details
C	SER110
F	SER110
I	SER110
L	SER110

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site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P09592

Chain	Residue	Details
C	THR113
K	CYS393
K	CYS413
K	CYS414
F	THR113
I	THR113
L	THR113
E	CYS413
E	CYS414
H	CYS393
H	CYS413
H	CYS414

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