Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6XMS

Structure of P5A-ATPase Spf1, AlF4-bound form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005215	molecular_function	transporter activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005739	cellular_component	mitochondrion
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005801	cellular_component	cis-Golgi network
A	0006874	biological_process	intracellular calcium ion homeostasis
A	0015031	biological_process	protein transport
A	0015662	molecular_function	P-type ion transporter activity
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0019829	molecular_function	ATPase-coupled monoatomic cation transmembrane transporter activity
A	0030026	biological_process	intracellular manganese ion homeostasis
A	0034214	biological_process	protein hexamerization
A	0043335	biological_process	protein unfolding
A	0046872	molecular_function	metal ion binding
A	0055085	biological_process	transmembrane transport
A	0055092	biological_process	sterol homeostasis
A	0070273	molecular_function	phosphatidylinositol-4-phosphate binding
A	0098655	biological_process	monoatomic cation transmembrane transport
A	0140358	molecular_function	P-type transmembrane transporter activity
A	0140567	molecular_function	membrane protein dislocase activity
A	0140569	biological_process	extraction of mislocalized protein from ER membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MG A 1301

Chain	Residue
A	ASP487
A	THR489
A	ASP816
A	ALF1302

site_id	AC2
Number of Residues	6
Details	binding site for residue ALF A 1302

Chain	Residue
A	MG1301
A	ASP487
A	THR489
A	THR697
A	GLY698
A	LYS797

Functional Information from PROSITE/UniProt

site_id	PS00154
Number of Residues	7
Details	ATPASE_E1_E2 E1-E2 ATPases phosphorylation site. DKTGTLT

Chain	Residue	Details
A	ASP487-THR493

site_id	PS01229
Number of Residues	23
Details	COF_2 Hypothetical cof family signature 2. CGDGtNDvgaLkqAhvGiaLlnG

Chain	Residue	Details
A	CYS814-GLY836

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	15
Details	Transmembrane: {"description":"Helical; Name=TMa","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	19
Details	Transmembrane: {"description":"Helical; Name=TMb","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	289
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	27
Details	Transmembrane: {"description":"Helical; Name=TM1","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	37
Details	Topological domain: {"description":"Lumenal","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	28
Details	Transmembrane: {"description":"Helical; Name=TM2","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	29
Details	Transmembrane: {"description":"Helical; Name=TM3","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	14
Details	Transmembrane: {"description":"Helical; Name=TM4a","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	18
Details	Transmembrane: {"description":"Helical; Name=TM4b","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	39
Details	Transmembrane: {"description":"Helical; Name=TM5","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	17
Details	Transmembrane: {"description":"Helical; Name=TM6","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	28
Details	Transmembrane: {"description":"Helical; Name=TM7","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	21
Details	Transmembrane: {"description":"Helical; Name=TM8","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	17
Details	Transmembrane: {"description":"Helical; Name=TM9","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	28
Details	Transmembrane: {"description":"Helical; Name=TM10","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	29
Details	Region: {"description":"A-domain; part 1","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	140
Details	Region: {"description":"A-domain; part 2","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	29
Details	Region: {"description":"P-domain; part 1","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	160
Details	Region: {"description":"P-domain; part 2","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	15
Details	Region: {"description":"P-domain; part 3","evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

site_id	SWS_FT_FI21
Number of Residues	1
Details	Active site: {"description":"4-aspartylphosphate intermediate","evidences":[{"source":"PubMed","id":"22745129","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"24392018","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"30785834","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"32353073","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI22
Number of Residues	11
Details	Binding site: {"evidences":[{"source":"PubMed","id":"32973005","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI23
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9Y2Q0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI24
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)