6XIY
Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to methyl 2-(acetylamino)-2-deoxy-1-thio-alpha-D-galactopyranose
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue Q3M A 401 |
| Chain | Residue |
| A | TYR236 |
| A | HOH529 |
| A | GLN267 |
| A | ASP269 |
| A | TRP271 |
| A | GLU280 |
| A | HIS286 |
| A | ASN292 |
| A | ASP293 |
| A | CA403 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| A | VAL218 |
| A | ASN220 |
| A | GLU224 |
| A | GLU305 |
| A | HOH524 |
| A | HOH545 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | GLN267 |
| A | ASP269 |
| A | GLU280 |
| A | ASN292 |
| A | ASP293 |
| A | Q3M401 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 404 |
| Chain | Residue |
| A | ASP243 |
| A | ASP270 |
| A | GLU280 |
| A | ASP281 |
| A | HOH520 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 405 |
| Chain | Residue |
| A | GLN272 |
| A | HOH544 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 406 |
| Chain | Residue |
| A | ARG298 |
| A | ARG298 |
| A | HOH573 |
| A | HOH573 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 407 |
| Chain | Residue |
| A | TRP194 |
| A | HIS197 |
| A | SER198 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 408 |
| Chain | Residue |
| A | ASP281 |
| A | CYS296 |
| A | HOH528 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 409 |
| Chain | Residue |
| A | ALA247 |
| A | TRP248 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 410 |
| Chain | Residue |
| A | LYS264 |
| A | ASP288 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 411 |
| Chain | Residue |
| A | GLN261 |
| A | ASN262 |
| A | TRP263 |
| A | HOH585 |
Functional Information from PROSITE/UniProt
| site_id | PS00615 |
| Number of Residues | 23 |
| Details | C_TYPE_LECTIN_1 C-type lectin domain signature. CAhfhpdgr.....WNDDVCqrpyh.WVC |
| Chain | Residue | Details |
| A | CYS282-CYS304 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 117 |
| Details | Domain: {"description":"C-type lectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00040","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33724805","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6PY1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6W12","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"6PY1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6W12","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
