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6XIP

The 1.5 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2

Functional Information from GO Data
ChainGOidnamespacecontents
A0004197molecular_functioncysteine-type endopeptidase activity
A0008242molecular_functionomega peptidase activity
A0016740molecular_functiontransferase activity
B0004197molecular_functioncysteine-type endopeptidase activity
B0008242molecular_functionomega peptidase activity
B0016740molecular_functiontransferase activity
C0004197molecular_functioncysteine-type endopeptidase activity
C0008242molecular_functionomega peptidase activity
C0016740molecular_functiontransferase activity
D0004197molecular_functioncysteine-type endopeptidase activity
D0008242molecular_functionomega peptidase activity
D0016740molecular_functiontransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues2
Detailsbinding site for residue EDO B 201
ChainResidue
BALA150
BARG190

site_idAC2
Number of Residues6
Detailsbinding site for residue EDO B 202
ChainResidue
BGLN157
BVAL159
BILE166
BVAL167
BLEU169
BHOH303

site_idAC3
Number of Residues6
Detailsbinding site for residue EDO C 101
ChainResidue
CTRP29
CALA30
CHOH202
CHOH205
DASN136
CSER24

site_idAC4
Number of Residues3
Detailsbinding site for residue EDO D 201
ChainResidue
DALA150
DARG190
DALA194

site_idAC5
Number of Residues6
Detailsbinding site for residue EDO D 202
ChainResidue
AARG21
BASP78
DASN105
DASN109
DASP112
DHOH327

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSITE: Cleavage; by 3CL-PRO => ECO:0000250|UniProtKB:P0C6V3
ChainResidueDetails
BGLN198
DGLN198

226707

PDB entries from 2024-10-30

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