6XI8

Yeast TFIIK (Kin28/Ccl1/Tfb3) Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0004693	molecular_function	cyclin-dependent protein serine/threonine kinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005675	cellular_component	transcription factor TFIIH holo complex
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006289	biological_process	nucleotide-excision repair
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006360	biological_process	transcription by RNA polymerase I
A	0006366	biological_process	transcription by RNA polymerase II
A	0006367	biological_process	transcription initiation at RNA polymerase II promoter
A	0006370	biological_process	7-methylguanosine mRNA capping
A	0006468	biological_process	protein phosphorylation
A	0006995	biological_process	cellular response to nitrogen starvation
A	0008353	molecular_function	RNA polymerase II CTD heptapeptide repeat kinase activity
A	0009891	biological_process	positive regulation of biosynthetic process
A	0010508	biological_process	positive regulation of autophagy
A	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0051301	biological_process	cell division
A	0051726	biological_process	regulation of cell cycle
A	0070985	cellular_component	transcription factor TFIIK complex
A	1902554	cellular_component	serine/threonine protein kinase complex
A	1905866	biological_process	positive regulation of Atg1/ULK1 kinase complex assembly
B	0006351	biological_process	DNA-templated transcription
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0016538	molecular_function	cyclin-dependent protein serine/threonine kinase regulator activity
B	0070985	cellular_component	transcription factor TFIIK complex

Functional Information from PROSITE/UniProt

site_id	PS00014
Number of Residues	4
Details	ER_TARGET Endoplasmic reticulum targeting sequence. SEEL

Chain	Residue	Details
C	SER318-LEU321

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site_id	PS00107
Number of Residues	24
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGEGTYAVVYlGcqhstgrk..........IAIK

Chain	Residue	Details
A	VAL13-LYS36

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site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IlHrDLKpnNLLF

Chain	Residue	Details
A	ILE125-PHE137

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027

Chain	Residue	Details
A	ASP129

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
A	LYS36
A	VAL13

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by CAK => ECO:0000269|PubMed:10373527, ECO:0000269|PubMed:11839796, ECO:0000269|PubMed:9774652

Chain	Residue	Details
A	TPO162

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