6XI4
Crystal structure of Maf domain of human N-acetylserotonin O-methyltransferase-like protein soaked with TFBQ
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 301 |
| Chain | Residue |
| A | PHE51 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 302 |
| Chain | Residue |
| A | GLU147 |
| A | LYS149 |
| A | HIS190 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 303 |
| Chain | Residue |
| A | MET184 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | LYS65 |
| A | ALA87 |
| A | LYS100 |
| A | HOH414 |
| A | SER19 |
| A | ALA20 |
| A | SER21 |
| A | ARG24 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 302 |
| Chain | Residue |
| B | ALA52 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| B | SER19 |
| B | ALA20 |
| B | SER21 |
| B | ARG24 |
| B | GLU44 |
| B | LYS65 |
| B | LYS100 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor; for pyrophosphatase activity => ECO:0000305|PubMed:24210219 |
| Chain | Residue | Details |
| A | ASP88 | |
| B | ASP88 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Important for substrate specificity; for pyrophosphatase activity => ECO:0000305|PubMed:24210219 |
| Chain | Residue | Details |
| A | ARG23 | |
| A | THR89 | |
| A | GLN179 | |
| B | ARG23 | |
| B | THR89 | |
| B | GLN179 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER21 | |
| B | SER21 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER228 | |
| B | SER228 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | THR234 | |
| B | THR234 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18318008, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER239 | |
| B | SER239 |
