6XHQ
Crystal structure of S. aureus TarI in complex with CDP-ribitol (space group C121)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0019350 | biological_process | teichoic acid biosynthetic process |
| A | 0047349 | molecular_function | D-ribitol-5-phosphate cytidylyltransferase activity |
| A | 0050518 | molecular_function | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity |
| A | 0070567 | molecular_function | cytidylyltransferase activity |
| A | 0071555 | biological_process | cell wall organization |
| A | 1902012 | biological_process | poly(ribitol phosphate) teichoic acid biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0019350 | biological_process | teichoic acid biosynthetic process |
| B | 0047349 | molecular_function | D-ribitol-5-phosphate cytidylyltransferase activity |
| B | 0050518 | molecular_function | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity |
| B | 0070567 | molecular_function | cytidylyltransferase activity |
| B | 0071555 | biological_process | cell wall organization |
| B | 1902012 | biological_process | poly(ribitol phosphate) teichoic acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | binding site for residue V2V A 301 |
| Chain | Residue |
| A | LEU7 |
| A | THR87 |
| A | ASP111 |
| A | ALA112 |
| A | VAL113 |
| A | ARG114 |
| A | GLY166 |
| A | GLN167 |
| A | GLN170 |
| A | SER193 |
| A | LYS217 |
| A | ALA8 |
| A | THR219 |
| A | HOH419 |
| A | HOH420 |
| A | HOH463 |
| A | HOH465 |
| B | ASP143 |
| B | THR144 |
| B | ARG160 |
| A | GLY9 |
| A | GLY10 |
| A | GLN23 |
| A | GLY81 |
| A | SER82 |
| A | ASP83 |
| A | ARG84 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | binding site for residue V2V B 301 |
| Chain | Residue |
| A | ASP143 |
| A | THR144 |
| A | ARG160 |
| B | LEU7 |
| B | ALA8 |
| B | GLY9 |
| B | GLY10 |
| B | GLY81 |
| B | SER82 |
| B | ASP83 |
| B | ARG84 |
| B | THR87 |
| B | ASP111 |
| B | ALA112 |
| B | VAL113 |
| B | ARG114 |
| B | GLY166 |
| B | GLN167 |
| B | THR168 |
| B | GLN170 |
| B | SER193 |
| B | LYS217 |
| B | THR219 |
| B | HOH419 |
Functional Information from PROSITE/UniProt
| site_id | PS01295 |
| Number of Residues | 8 |
| Details | ISPD 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. IVTHDAVR |
| Chain | Residue | Details |
| A | ILE107-ARG114 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02068","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_02068","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Positions ribitol 5-phosphate for the nucleophilic attack","evidences":[{"source":"HAMAP-Rule","id":"MF_02068","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
