Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6XE0

Cryo-EM structure of NusG-CTD bound to 70S ribosome (30S: NusG-CTD fragment)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000028	biological_process	ribosomal small subunit assembly
A	0002181	biological_process	cytoplasmic translation
A	0003735	molecular_function	structural constituent of ribosome
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005840	cellular_component	ribosome
A	0006412	biological_process	translation
A	0008270	molecular_function	zinc ion binding
A	0015935	cellular_component	small ribosomal subunit
A	0022627	cellular_component	cytosolic small ribosomal subunit
A	1990904	cellular_component	ribonucleoprotein complex
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
B	0003735	molecular_function	structural constituent of ribosome
B	0006412	biological_process	translation
C	0000028	biological_process	ribosomal small subunit assembly
C	0000900	molecular_function	mRNA regulatory element binding translation repressor activity
C	0002181	biological_process	cytoplasmic translation
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005840	cellular_component	ribosome
C	0006353	biological_process	DNA-templated transcription termination
C	0006412	biological_process	translation
C	0006417	biological_process	regulation of translation
C	0015935	cellular_component	small ribosomal subunit
C	0019843	molecular_function	rRNA binding
C	0022627	cellular_component	cytosolic small ribosomal subunit
C	0031564	biological_process	transcription antitermination
C	0042254	biological_process	ribosome biogenesis
C	0042274	biological_process	ribosomal small subunit biogenesis
C	0045947	biological_process	negative regulation of translational initiation
C	0046677	biological_process	response to antibiotic
C	0048027	molecular_function	mRNA 5'-UTR binding
C	1990145	biological_process	maintenance of translational fidelity
C	1990904	cellular_component	ribonucleoprotein complex
D	0000028	biological_process	ribosomal small subunit assembly
D	0002181	biological_process	cytoplasmic translation
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0015935	cellular_component	small ribosomal subunit
D	0019843	molecular_function	rRNA binding
D	0022627	cellular_component	cytosolic small ribosomal subunit
D	0043229	cellular_component	intracellular organelle
D	0046677	biological_process	response to antibiotic
D	1990145	biological_process	maintenance of translational fidelity
D	1990904	cellular_component	ribonucleoprotein complex
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0019843	molecular_function	rRNA binding
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0006412	biological_process	translation
F	0015935	cellular_component	small ribosomal subunit
G	0000028	biological_process	ribosomal small subunit assembly
G	0002181	biological_process	cytoplasmic translation
G	0003735	molecular_function	structural constituent of ribosome
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0006417	biological_process	regulation of translation
G	0019843	molecular_function	rRNA binding
G	0022627	cellular_component	cytosolic small ribosomal subunit
G	0043229	cellular_component	intracellular organelle
G	0043488	biological_process	regulation of mRNA stability
G	1990904	cellular_component	ribonucleoprotein complex
H	0000049	molecular_function	tRNA binding
H	0002181	biological_process	cytoplasmic translation
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0022627	cellular_component	cytosolic small ribosomal subunit
H	0043229	cellular_component	intracellular organelle
H	1990904	cellular_component	ribonucleoprotein complex
I	0000049	molecular_function	tRNA binding
I	0001072	molecular_function	transcription antitermination factor activity, RNA binding
I	0002181	biological_process	cytoplasmic translation
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0008023	cellular_component	transcription elongation factor complex
I	0015935	cellular_component	small ribosomal subunit
I	0022627	cellular_component	cytosolic small ribosomal subunit
I	0031564	biological_process	transcription antitermination
I	0032784	biological_process	regulation of DNA-templated transcription elongation
I	0042254	biological_process	ribosome biogenesis
I	1990904	cellular_component	ribonucleoprotein complex
J	0002181	biological_process	cytoplasmic translation
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0019843	molecular_function	rRNA binding
J	0022627	cellular_component	cytosolic small ribosomal subunit
J	0070181	molecular_function	small ribosomal subunit rRNA binding
J	1990904	cellular_component	ribonucleoprotein complex
K	0000049	molecular_function	tRNA binding
K	0000372	biological_process	Group I intron splicing
K	0002181	biological_process	cytoplasmic translation
K	0003735	molecular_function	structural constituent of ribosome
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0015935	cellular_component	small ribosomal subunit
K	0019843	molecular_function	rRNA binding
K	0022627	cellular_component	cytosolic small ribosomal subunit
K	0033120	biological_process	positive regulation of RNA splicing
K	0034336	molecular_function	misfolded RNA binding
K	0034337	biological_process	RNA folding
K	0046677	biological_process	response to antibiotic
K	1990145	biological_process	maintenance of translational fidelity
K	1990904	cellular_component	ribonucleoprotein complex
L	0000049	molecular_function	tRNA binding
L	0002181	biological_process	cytoplasmic translation
L	0003676	molecular_function	nucleic acid binding
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0015935	cellular_component	small ribosomal subunit
L	0019843	molecular_function	rRNA binding
L	0022627	cellular_component	cytosolic small ribosomal subunit
L	1990904	cellular_component	ribonucleoprotein complex
M	0000028	biological_process	ribosomal small subunit assembly
M	0000049	molecular_function	tRNA binding
M	0002181	biological_process	cytoplasmic translation
M	0003735	molecular_function	structural constituent of ribosome
M	0005737	cellular_component	cytoplasm
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0015935	cellular_component	small ribosomal subunit
M	0019843	molecular_function	rRNA binding
M	0022627	cellular_component	cytosolic small ribosomal subunit
M	0043229	cellular_component	intracellular organelle
M	1990904	cellular_component	ribonucleoprotein complex
O	0000028	biological_process	ribosomal small subunit assembly
O	0002181	biological_process	cytoplasmic translation
O	0003735	molecular_function	structural constituent of ribosome
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0006417	biological_process	regulation of translation
O	0019843	molecular_function	rRNA binding
O	0022627	cellular_component	cytosolic small ribosomal subunit
O	0043229	cellular_component	intracellular organelle
O	0070181	molecular_function	small ribosomal subunit rRNA binding
O	1990904	cellular_component	ribonucleoprotein complex
P	0000028	biological_process	ribosomal small subunit assembly
P	0000400	molecular_function	four-way junction DNA binding
P	0002181	biological_process	cytoplasmic translation
P	0003735	molecular_function	structural constituent of ribosome
P	0004519	molecular_function	endonuclease activity
P	0004520	molecular_function	DNA endonuclease activity
P	0005737	cellular_component	cytoplasm
P	0005840	cellular_component	ribosome
P	0006259	biological_process	DNA metabolic process
P	0006412	biological_process	translation
P	0015935	cellular_component	small ribosomal subunit
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	0043229	cellular_component	intracellular organelle
P	1990904	cellular_component	ribonucleoprotein complex
Q	0000028	biological_process	ribosomal small subunit assembly
Q	0002181	biological_process	cytoplasmic translation
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0008270	molecular_function	zinc ion binding
Q	0019843	molecular_function	rRNA binding
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	0046677	biological_process	response to antibiotic
Q	0060090	molecular_function	molecular adaptor activity
Q	0070181	molecular_function	small ribosomal subunit rRNA binding
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003735	molecular_function	structural constituent of ribosome
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015935	cellular_component	small ribosomal subunit
T	0000028	biological_process	ribosomal small subunit assembly
T	0002181	biological_process	cytoplasmic translation
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0008073	molecular_function	ornithine decarboxylase inhibitor activity
T	0015935	cellular_component	small ribosomal subunit
T	0019843	molecular_function	rRNA binding
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	0070181	molecular_function	small ribosomal subunit rRNA binding
T	1990904	cellular_component	ribonucleoprotein complex
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
V	0005515	molecular_function	protein binding
V	0005829	cellular_component	cytosol
V	0006353	biological_process	DNA-templated transcription termination
V	0006354	biological_process	DNA-templated transcription elongation
V	0008023	cellular_component	transcription elongation factor complex
V	0031564	biological_process	transcription antitermination
V	0032784	biological_process	regulation of DNA-templated transcription elongation
V	0042254	biological_process	ribosome biogenesis
V	0140673	biological_process	transcription elongation-coupled chromatin remodeling

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. SeLlakFVnilmvdGKKstaesIVysA

Chain	Residue	Details
F	SER19-ALA45

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GiaVVSTSkGVMtdraAR

Chain	Residue	Details
G	GLY99-ARG116

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. IrALnaA.GFrItnitDvTPiPHN

Chain	Residue	Details
J	ILE96-ASN118

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR

Chain	Residue	Details
K	LYS42-ARG49

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIrEcRPLS

Chain	Residue	Details
Q	GLY55-SER67

site_id	PS00057
Number of Residues	24
Details	RIBOSOMAL_S18 Ribosomal protein S18 signature. IDYkd.IatLknYITEs.GKIvpsRI

Chain	Residue	Details
R	ILE20-ILE43

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. PdhkhavialTsiYGVGKTRSkAILaAAG

Chain	Residue	Details
L	PRO9-GLY37

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGRqhvpvfVtdemVGhkLGEFapT

Chain	Residue	Details
S	ASN52-THR76

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGisGQagAirhGiTRAL

Chain	Residue	Details
H	GLY68-LEU86

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkrtGAqvrGPIpLPT

Chain	Residue	Details
I	ALA29-THR44

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. LqgHFaehKkDhhSrrgLlrMvsqrrkLldY

Chain	Residue	Details
O	LEU38-TYR68

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CrqtgrphgflrkFGLSRiKVR

Chain	Residue	Details
M	ARG63-ARG85

site_id	PS00548
Number of Residues	35
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewyreGrVplHt..LradIDyntseahTtyGviG

Chain	Residue	Details
B	ALA162-GLY196

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRifsFtAltVVGDgn.GrVGfGygkar.EVpa.AI

Chain	Residue	Details
D	GLY27-ILE59

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LEgRLdnvVYRmgfGaTraeARqLV

Chain	Residue	Details
C	LEU93-VAL117

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ

Chain	Residue	Details
L	ARG86-GLN99

site_id	PS00732
Number of Residues	10
Details	RIBOSOMAL_S16 Ribosomal protein S16 signature. VtIRLARHGA

Chain	Residue	Details
P	VAL2-ALA11

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PdaLFViDadhEhiaIkEannlGIP

Chain	Residue	Details
A	PRO157-PRO181

site_id	PS01014
Number of Residues	10
Details	NUSG Transcription termination factor nusG signature. IFGRaTPVeL

Chain	Residue	Details
V	ILE164-LEU173

site_id	PS01048
Number of Residues	10
Details	RIBOSOMAL_S6 Ribosomal protein S6 signature. GrRQLAYpIN

Chain	Residue	Details
E	GLY43-ASN52

site_id	PS01181
Number of Residues	13
Details	RIBOSOMAL_S21 Ribosomal protein S21 signature. DvALRRFKRsceK

Chain	Residue	Details
U	ASP12-LYS24

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: 3-methylthioaspartic acid => ECO:0000269\|PubMed:8844851

Chain	Residue	Details
K	ASP88

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000269\|PubMed:18723842

Chain	Residue	Details
K	LYS107

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)