6XDC

Cryo-EM structure of SARS-CoV-2 ORF3a

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005216	molecular_function	monoatomic ion channel activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005886	cellular_component	plasma membrane
A	0005891	cellular_component	voltage-gated calcium channel complex
A	0006811	biological_process	monoatomic ion transport
A	0008076	cellular_component	voltage-gated potassium channel complex
A	0009898	cellular_component	cytoplasmic side of plasma membrane
A	0015267	molecular_function	channel activity
A	0016020	cellular_component	membrane
A	0020002	cellular_component	host cell plasma membrane
A	0030430	cellular_component	host cell cytoplasm
A	0033644	cellular_component	host cell membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0039520	biological_process	symbiont-mediated activation of host autophagy
A	0042802	molecular_function	identical protein binding
A	0044165	cellular_component	host cell endoplasmic reticulum
A	0044167	cellular_component	host cell endoplasmic reticulum membrane
A	0044174	cellular_component	host cell endosome
A	0044187	cellular_component	host cell lysosome
A	0044423	cellular_component	virion component
A	0055036	cellular_component	virion membrane
A	0098662	biological_process	inorganic cation transmembrane transport
A	0140677	molecular_function	molecular function activator activity
A	0140883	biological_process	symbiont-mediated activation of host reticulophagy
B	0005216	molecular_function	monoatomic ion channel activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005886	cellular_component	plasma membrane
B	0005891	cellular_component	voltage-gated calcium channel complex
B	0006811	biological_process	monoatomic ion transport
B	0008076	cellular_component	voltage-gated potassium channel complex
B	0009898	cellular_component	cytoplasmic side of plasma membrane
B	0015267	molecular_function	channel activity
B	0016020	cellular_component	membrane
B	0020002	cellular_component	host cell plasma membrane
B	0030430	cellular_component	host cell cytoplasm
B	0033644	cellular_component	host cell membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0039520	biological_process	symbiont-mediated activation of host autophagy
B	0042802	molecular_function	identical protein binding
B	0044165	cellular_component	host cell endoplasmic reticulum
B	0044167	cellular_component	host cell endoplasmic reticulum membrane
B	0044174	cellular_component	host cell endosome
B	0044187	cellular_component	host cell lysosome
B	0044423	cellular_component	virion component
B	0055036	cellular_component	virion membrane
B	0098662	biological_process	inorganic cation transmembrane transport
B	0140677	molecular_function	molecular function activator activity
B	0140883	biological_process	symbiont-mediated activation of host reticulophagy

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	134
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"34158638","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	10
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"34158638","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	14
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"34158638","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Involved in polymerization","evidences":[{"source":"UniProtKB","id":"P59632","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---