6X9N
Pseudomonas aeruginosa MurC with AZ5595
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008360 | biological_process | regulation of cell shape |
| A | 0008763 | molecular_function | UDP-N-acetylmuramate-L-alanine ligase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0016881 | molecular_function | acid-amino acid ligase activity |
| A | 0051301 | biological_process | cell division |
| A | 0071555 | biological_process | cell wall organization |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008360 | biological_process | regulation of cell shape |
| B | 0008763 | molecular_function | UDP-N-acetylmuramate-L-alanine ligase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016874 | molecular_function | ligase activity |
| B | 0016881 | molecular_function | acid-amino acid ligase activity |
| B | 0051301 | biological_process | cell division |
| B | 0071555 | biological_process | cell wall organization |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008360 | biological_process | regulation of cell shape |
| C | 0008763 | molecular_function | UDP-N-acetylmuramate-L-alanine ligase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009252 | biological_process | peptidoglycan biosynthetic process |
| C | 0016874 | molecular_function | ligase activity |
| C | 0016881 | molecular_function | acid-amino acid ligase activity |
| C | 0051301 | biological_process | cell division |
| C | 0071555 | biological_process | cell wall organization |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008360 | biological_process | regulation of cell shape |
| D | 0008763 | molecular_function | UDP-N-acetylmuramate-L-alanine ligase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009252 | biological_process | peptidoglycan biosynthetic process |
| D | 0016874 | molecular_function | ligase activity |
| D | 0016881 | molecular_function | acid-amino acid ligase activity |
| D | 0051301 | biological_process | cell division |
| D | 0071555 | biological_process | cell wall organization |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0008360 | biological_process | regulation of cell shape |
| E | 0008763 | molecular_function | UDP-N-acetylmuramate-L-alanine ligase activity |
| E | 0009058 | biological_process | biosynthetic process |
| E | 0009252 | biological_process | peptidoglycan biosynthetic process |
| E | 0016874 | molecular_function | ligase activity |
| E | 0016881 | molecular_function | acid-amino acid ligase activity |
| E | 0051301 | biological_process | cell division |
| E | 0071555 | biological_process | cell wall organization |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0008360 | biological_process | regulation of cell shape |
| F | 0008763 | molecular_function | UDP-N-acetylmuramate-L-alanine ligase activity |
| F | 0009058 | biological_process | biosynthetic process |
| F | 0009252 | biological_process | peptidoglycan biosynthetic process |
| F | 0016874 | molecular_function | ligase activity |
| F | 0016881 | molecular_function | acid-amino acid ligase activity |
| F | 0051301 | biological_process | cell division |
| F | 0071555 | biological_process | cell wall organization |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0005524 | molecular_function | ATP binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0008360 | biological_process | regulation of cell shape |
| G | 0008763 | molecular_function | UDP-N-acetylmuramate-L-alanine ligase activity |
| G | 0009058 | biological_process | biosynthetic process |
| G | 0009252 | biological_process | peptidoglycan biosynthetic process |
| G | 0016874 | molecular_function | ligase activity |
| G | 0016881 | molecular_function | acid-amino acid ligase activity |
| G | 0051301 | biological_process | cell division |
| G | 0071555 | biological_process | cell wall organization |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0005524 | molecular_function | ATP binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0008360 | biological_process | regulation of cell shape |
| H | 0008763 | molecular_function | UDP-N-acetylmuramate-L-alanine ligase activity |
| H | 0009058 | biological_process | biosynthetic process |
| H | 0009252 | biological_process | peptidoglycan biosynthetic process |
| H | 0016874 | molecular_function | ligase activity |
| H | 0016881 | molecular_function | acid-amino acid ligase activity |
| H | 0051301 | biological_process | cell division |
| H | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue UYD A 501 |
| Chain | Residue |
| A | GLY125 |
| A | EDO504 |
| A | HOH649 |
| A | HOH659 |
| A | HOH686 |
| C | ASP192 |
| C | UYD501 |
| A | THR128 |
| A | THR189 |
| A | ASN190 |
| A | CYS226 |
| A | TYR246 |
| A | HIS288 |
| A | LEU291 |
| A | ASN292 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | PRO273 |
| A | VAL298 |
| A | THR301 |
| A | ASP302 |
| A | HOH631 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | PRO103 |
| A | GLU106 |
| A | HIS180 |
| G | ARG241 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | ASP228 |
| A | LEU291 |
| A | UYD501 |
| C | PRO230 |
| C | HOH616 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | PRO277 |
| A | LEU278 |
| A | ASP279 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 506 |
| Chain | Residue |
| A | LEU142 |
| A | ARG165 |
| A | TYR166 |
| A | GLU303 |
| A | GLY304 |
| A | ILE305 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 507 |
| Chain | Residue |
| A | VAL101 |
| site_id | AC8 |
| Number of Residues | 13 |
| Details | binding site for residue UYD B 501 |
| Chain | Residue |
| B | GLY125 |
| B | THR189 |
| B | ASN190 |
| B | CYS226 |
| B | TYR246 |
| B | HIS288 |
| B | LEU291 |
| B | ASN292 |
| B | HOH666 |
| B | HOH681 |
| B | HOH694 |
| H | ASP192 |
| H | UYD502 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| B | ARG115 |
| B | ALA163 |
| B | SER164 |
| B | ARG165 |
| B | HOH610 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | GLU212 |
| B | ASN216 |
| E | LEU179 |
| E | HIS180 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | PRO103 |
| B | GLU106 |
| B | HIS180 |
| B | HOH706 |
| E | ARG241 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | HIS116 |
| B | ARG165 |
| B | TYR166 |
| B | GLU303 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| B | ASP228 |
| B | LEU291 |
| B | HOH666 |
| H | PRO230 |
| H | HOH628 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 507 |
| Chain | Residue |
| B | PRO277 |
| B | LEU278 |
| B | ASP279 |
| B | HOH625 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 508 |
| Chain | Residue |
| B | ALA26 |
| B | GLY27 |
| B | GLY30 |
| B | ARG151 |
| B | LEU152 |
| B | HOH654 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 509 |
| Chain | Residue |
| B | THR245 |
| B | ASP251 |
| E | ARG98 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue DMS B 510 |
| Chain | Residue |
| B | LEU142 |
| B | ARG165 |
| B | TYR166 |
| B | GLU303 |
| B | GLY304 |
| B | HOH608 |
| D | HOH665 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue DMS B 511 |
| Chain | Residue |
| H | ASP228 |
| H | PRO230 |
| H | ARG233 |
| H | HOH626 |
| B | VAL227 |
| B | PRO230 |
| B | ARG233 |
| H | VAL227 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 512 |
| Chain | Residue |
| B | ARG16 |
| B | LEU38 |
| B | GLY39 |
| B | TYR40 |
| site_id | AE2 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 513 |
| Chain | Residue |
| B | VAL101 |
| site_id | AE3 |
| Number of Residues | 14 |
| Details | binding site for residue UYD C 501 |
| Chain | Residue |
| A | ASP192 |
| A | UYD501 |
| C | HIS124 |
| C | GLY125 |
| C | THR189 |
| C | ASN190 |
| C | CYS226 |
| C | TYR246 |
| C | HIS288 |
| C | LEU291 |
| C | ASN292 |
| C | EDO503 |
| C | HOH646 |
| C | HOH657 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 502 |
| Chain | Residue |
| C | PRO103 |
| C | GLU106 |
| C | HIS180 |
| D | ARG241 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 503 |
| Chain | Residue |
| A | PRO230 |
| A | HOH640 |
| C | ASP228 |
| C | LEU291 |
| C | UYD501 |
| site_id | AE6 |
| Number of Residues | 9 |
| Details | binding site for residue EDO C 504 |
| Chain | Residue |
| A | VAL227 |
| A | ASP228 |
| A | ARG233 |
| C | VAL227 |
| C | ASP228 |
| C | ASP229 |
| C | PRO230 |
| C | ARG233 |
| C | HOH665 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 505 |
| Chain | Residue |
| C | THR245 |
| C | ASP251 |
| C | ALA252 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue DMS C 506 |
| Chain | Residue |
| C | ARG165 |
| C | TYR166 |
| C | GLU303 |
| C | GLY304 |
| C | HOH620 |
| E | HOH609 |
| site_id | AE9 |
| Number of Residues | 1 |
| Details | binding site for residue CL C 507 |
| Chain | Residue |
| C | VAL101 |
| site_id | AF1 |
| Number of Residues | 15 |
| Details | binding site for residue UYD D 501 |
| Chain | Residue |
| D | HIS124 |
| D | GLY125 |
| D | THR128 |
| D | THR189 |
| D | ASN190 |
| D | CYS226 |
| D | TYR246 |
| D | HIS288 |
| D | LEU291 |
| D | ASN292 |
| D | EDO504 |
| D | HOH645 |
| D | HOH667 |
| G | ASP192 |
| G | UYD501 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 502 |
| Chain | Residue |
| C | GLU212 |
| C | ASN216 |
| D | LEU179 |
| D | HIS180 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 503 |
| Chain | Residue |
| C | ARG241 |
| D | PRO103 |
| D | GLU106 |
| D | HIS180 |
| D | HOH688 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 504 |
| Chain | Residue |
| D | ASP228 |
| D | LEU291 |
| D | UYD501 |
| D | HOH633 |
| D | HOH645 |
| G | PRO230 |
| site_id | AF5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 505 |
| Chain | Residue |
| D | PRO277 |
| D | ASP279 |
| D | HOH632 |
| site_id | AF6 |
| Number of Residues | 5 |
| Details | binding site for residue DMS D 506 |
| Chain | Residue |
| D | ARG165 |
| D | TYR166 |
| D | GLU303 |
| D | GLY304 |
| D | ILE305 |
| site_id | AF7 |
| Number of Residues | 10 |
| Details | binding site for residue DMS D 507 |
| Chain | Residue |
| D | VAL227 |
| D | ASP228 |
| D | ASP229 |
| D | PRO230 |
| D | ARG233 |
| D | HOH672 |
| G | VAL227 |
| G | ASP228 |
| G | ASP229 |
| G | PRO230 |
| site_id | AF8 |
| Number of Residues | 1 |
| Details | binding site for residue CL D 508 |
| Chain | Residue |
| D | VAL101 |
| site_id | AF9 |
| Number of Residues | 15 |
| Details | binding site for residue UYD E 501 |
| Chain | Residue |
| E | HIS124 |
| E | GLY125 |
| E | THR128 |
| E | THR189 |
| E | ASN190 |
| E | CYS226 |
| E | TYR246 |
| E | HIS288 |
| E | LEU291 |
| E | ASN292 |
| E | EDO504 |
| E | HOH671 |
| E | HOH691 |
| F | ASP192 |
| F | UYD501 |
| site_id | AG1 |
| Number of Residues | 1 |
| Details | binding site for residue EDO E 502 |
| Chain | Residue |
| F | ASP251 |
| site_id | AG2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO E 503 |
| Chain | Residue |
| E | ASN204 |
| E | LYS207 |
| E | GLU234 |
| F | ALA256 |
| F | ILE257 |
| F | HOH662 |
| F | HOH694 |
| site_id | AG3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 504 |
| Chain | Residue |
| E | ASP228 |
| E | UYD501 |
| F | PRO230 |
| F | HOH632 |
| site_id | AG4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO E 505 |
| Chain | Residue |
| E | PRO277 |
| E | LEU278 |
| E | ASP279 |
| site_id | AG5 |
| Number of Residues | 5 |
| Details | binding site for residue DMS E 506 |
| Chain | Residue |
| E | ARG165 |
| E | TYR166 |
| E | GLU303 |
| E | HOH622 |
| E | HOH634 |
| site_id | AG6 |
| Number of Residues | 3 |
| Details | binding site for residue DMS E 507 |
| Chain | Residue |
| E | ARG16 |
| E | LEU38 |
| E | TYR40 |
| site_id | AG7 |
| Number of Residues | 1 |
| Details | binding site for residue CL E 508 |
| Chain | Residue |
| E | VAL101 |
| site_id | AG8 |
| Number of Residues | 14 |
| Details | binding site for residue UYD F 501 |
| Chain | Residue |
| E | ASP192 |
| E | UYD501 |
| F | GLY125 |
| F | THR128 |
| F | THR189 |
| F | ASN190 |
| F | CYS226 |
| F | TYR246 |
| F | HIS288 |
| F | LEU291 |
| F | ASN292 |
| F | EDO505 |
| F | HOH664 |
| F | HOH674 |
| site_id | AG9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO F 502 |
| Chain | Residue |
| F | LEU108 |
| F | ALA109 |
| F | ALA169 |
| F | GLU170 |
| F | LEU181 |
| F | HOH606 |
| F | HOH685 |
| site_id | AH1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO F 503 |
| Chain | Residue |
| F | LEU236 |
| F | THR245 |
| F | ASP251 |
| F | ALA252 |
| site_id | AH2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO F 504 |
| Chain | Residue |
| F | PRO103 |
| F | GLU106 |
| F | HIS180 |
| H | ARG241 |
| site_id | AH3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO F 505 |
| Chain | Residue |
| E | PRO230 |
| F | ASP228 |
| F | LEU291 |
| F | UYD501 |
| site_id | AH4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO F 506 |
| Chain | Residue |
| F | PRO277 |
| F | LEU278 |
| F | ASP279 |
| F | HOH619 |
| site_id | AH5 |
| Number of Residues | 5 |
| Details | binding site for residue DMS F 507 |
| Chain | Residue |
| F | ARG165 |
| F | TYR166 |
| F | GLU303 |
| F | HOH631 |
| F | HOH657 |
| site_id | AH6 |
| Number of Residues | 12 |
| Details | binding site for residue DMS F 508 |
| Chain | Residue |
| E | VAL227 |
| E | ASP228 |
| E | ASP229 |
| E | PRO230 |
| E | ARG233 |
| F | VAL227 |
| F | ASP228 |
| F | ASP229 |
| F | PRO230 |
| F | ARG233 |
| F | HOH646 |
| F | HOH693 |
| site_id | AH7 |
| Number of Residues | 1 |
| Details | binding site for residue CL F 509 |
| Chain | Residue |
| F | VAL101 |
| site_id | AH8 |
| Number of Residues | 13 |
| Details | binding site for residue UYD G 501 |
| Chain | Residue |
| D | ASP192 |
| D | UYD501 |
| G | HIS124 |
| G | GLY125 |
| G | THR189 |
| G | ASN190 |
| G | CYS226 |
| G | TYR246 |
| G | HIS288 |
| G | LEU291 |
| G | ASN292 |
| G | EDO503 |
| G | HOH656 |
| site_id | AH9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO G 502 |
| Chain | Residue |
| A | HIS215 |
| A | ARG241 |
| G | PRO103 |
| G | GLU106 |
| G | HIS180 |
| site_id | AI1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO G 503 |
| Chain | Residue |
| D | PRO230 |
| D | HOH686 |
| G | ASP228 |
| G | LEU291 |
| G | UYD501 |
| site_id | AI2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO G 504 |
| Chain | Residue |
| G | PRO277 |
| G | LEU278 |
| G | ASP279 |
| site_id | AI3 |
| Number of Residues | 5 |
| Details | binding site for residue DMS G 505 |
| Chain | Residue |
| G | ARG165 |
| G | TYR166 |
| G | GLU303 |
| G | GLY304 |
| G | ILE305 |
| site_id | AI4 |
| Number of Residues | 2 |
| Details | binding site for residue VAL H 501 |
| Chain | Residue |
| H | THR127 |
| H | GLY319 |
| site_id | AI5 |
| Number of Residues | 15 |
| Details | binding site for residue UYD H 502 |
| Chain | Residue |
| B | ASP192 |
| B | UYD501 |
| H | HIS124 |
| H | GLY125 |
| H | THR128 |
| H | THR189 |
| H | ASN190 |
| H | CYS226 |
| H | TYR246 |
| H | HIS288 |
| H | LEU291 |
| H | ASN292 |
| H | EDO504 |
| H | HOH675 |
| H | HOH681 |
| site_id | AI6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO H 503 |
| Chain | Residue |
| F | ALA240 |
| F | ARG241 |
| H | PRO103 |
| H | GLU106 |
| H | HIS180 |
| site_id | AI7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO H 504 |
| Chain | Residue |
| B | PRO230 |
| B | HOH681 |
| B | HOH694 |
| H | ASP228 |
| H | LEU291 |
| H | UYD502 |
| site_id | AI8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO H 505 |
| Chain | Residue |
| H | PRO277 |
| H | LEU278 |
| H | ASP279 |
| H | HOH679 |
| site_id | AI9 |
| Number of Residues | 3 |
| Details | binding site for residue DMS H 506 |
| Chain | Residue |
| H | GLU303 |
| H | GLY304 |
| H | HOH605 |
| site_id | AJ1 |
| Number of Residues | 1 |
| Details | binding site for residue CL H 507 |
| Chain | Residue |
| H | VAL101 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00046 |
| Chain | Residue | Details |
| A | GLY122 | |
| B | GLY122 | |
| C | GLY122 | |
| D | GLY122 | |
| E | GLY122 | |
| F | GLY122 | |
| G | GLY122 | |
| H | GLY122 |
