6X8R

Pharmacological characterisation and NMR structure of the novel mu-conotoxin SxIIIC, a potent irreversible NaV channel inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0017080	molecular_function	sodium channel regulator activity
A	0019871	molecular_function	sodium channel inhibitor activity
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
A	0099106	molecular_function	ion channel regulator activity

Functional Information from PROSITE/UniProt

site_id	PS60013
Number of Residues	20
Details	MU_CONOTOXIN Mu-conotoxin family signature. CCNGRggCSSRWCRDHaRCC

Chain	Residue	Details
A	CYS3-CYS22

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	21
Details	Peptide: {"description":"Mu-conotoxin SxIIIC","featureId":"PRO_0000453397","evidences":[{"source":"PubMed","id":"33023152","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Cysteine amide","evidences":[{"source":"PubMed","id":"33023152","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---