Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6X89

Vigna radiata mitochondrial complex I*

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1M	0016020	cellular_component	membrane
2M	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
2M	0042773	biological_process	ATP synthesis coupled electron transport
3M	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
3M	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
4L	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
4L	0042773	biological_process	ATP synthesis coupled electron transport
6M	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A1	0005743	cellular_component	mitochondrial inner membrane
A1	0022904	biological_process	respiratory electron transport chain
A2	0005743	cellular_component	mitochondrial inner membrane
A2	0022904	biological_process	respiratory electron transport chain
A5	0005743	cellular_component	mitochondrial inner membrane
A5	0022904	biological_process	respiratory electron transport chain
A6	0005743	cellular_component	mitochondrial inner membrane
A6	0006979	biological_process	response to oxidative stress
A6	0022904	biological_process	respiratory electron transport chain
A6	0045271	cellular_component	respiratory chain complex I
A8	0005739	cellular_component	mitochondrion
A8	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
A8	0022904	biological_process	respiratory electron transport chain
A9	0000166	molecular_function	nucleotide binding
A9	0005739	cellular_component	mitochondrion
A9	0044877	molecular_function	protein-containing complex binding
AL	0005743	cellular_component	mitochondrial inner membrane
AL	0006979	biological_process	response to oxidative stress
AL	0016020	cellular_component	membrane
AL	0022904	biological_process	respiratory electron transport chain
AL	0045271	cellular_component	respiratory chain complex I
AM	0005739	cellular_component	mitochondrion
AM	0005743	cellular_component	mitochondrial inner membrane
AM	0016020	cellular_component	membrane
AM	0022904	biological_process	respiratory electron transport chain
AM	0045271	cellular_component	respiratory chain complex I
G1	0031966	cellular_component	mitochondrial membrane
G1	0046872	molecular_function	metal ion binding
G2	0009853	biological_process	photorespiration
G2	0031966	cellular_component	mitochondrial membrane
G2	0045271	cellular_component	respiratory chain complex I
G2	0046872	molecular_function	metal ion binding
L2	0031966	cellular_component	mitochondrial membrane
S1	0005743	cellular_component	mitochondrial inner membrane
S1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S1	0016020	cellular_component	membrane
S1	0016491	molecular_function	oxidoreductase activity
S1	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S1	0022904	biological_process	respiratory electron transport chain
S1	0042773	biological_process	ATP synthesis coupled electron transport
S1	0046872	molecular_function	metal ion binding
S1	0051536	molecular_function	iron-sulfur cluster binding
S1	0051537	molecular_function	2 iron, 2 sulfur cluster binding
S1	0051539	molecular_function	4 iron, 4 sulfur cluster binding
S1	1902600	biological_process	proton transmembrane transport
S2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S2	0048038	molecular_function	quinone binding
S2	0051287	molecular_function	NAD binding
S3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S3	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S4	0005743	cellular_component	mitochondrial inner membrane
S4	0022900	biological_process	electron transport chain
S4	0022904	biological_process	respiratory electron transport chain
S5	0003676	molecular_function	nucleic acid binding
S5	0003723	molecular_function	RNA binding
S5	0003729	molecular_function	mRNA binding
S5	0005634	cellular_component	nucleus
S5	0005654	cellular_component	nucleoplasm
S5	0005681	cellular_component	spliceosomal complex
S5	0005737	cellular_component	cytoplasm
S5	0006397	biological_process	mRNA processing
S5	0008380	biological_process	RNA splicing
S5	0016607	cellular_component	nuclear speck
S6	0005739	cellular_component	mitochondrion
S6	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S6	0046872	molecular_function	metal ion binding
S7	0005739	cellular_component	mitochondrion
S7	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S7	0009060	biological_process	aerobic respiration
S7	0015990	biological_process	electron transport coupled proton transport
S7	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S7	0045271	cellular_component	respiratory chain complex I
S7	0046872	molecular_function	metal ion binding
S7	0048038	molecular_function	quinone binding
S7	0051536	molecular_function	iron-sulfur cluster binding
S7	0051539	molecular_function	4 iron, 4 sulfur cluster binding
S8	0003954	molecular_function	NADH dehydrogenase activity
S8	0005739	cellular_component	mitochondrion
S8	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S8	0009060	biological_process	aerobic respiration
S8	0016020	cellular_component	membrane
S8	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S8	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S8	0046872	molecular_function	metal ion binding
S8	0051536	molecular_function	iron-sulfur cluster binding
S8	0051539	molecular_function	4 iron, 4 sulfur cluster binding
V1	0000166	molecular_function	nucleotide binding
V1	0005739	cellular_component	mitochondrion
V1	0005743	cellular_component	mitochondrial inner membrane
V1	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
V1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
V1	0010181	molecular_function	FMN binding
V1	0022904	biological_process	respiratory electron transport chain
V1	0046872	molecular_function	metal ion binding
V1	0051287	molecular_function	NAD binding
V1	0051536	molecular_function	iron-sulfur cluster binding
V1	0051539	molecular_function	4 iron, 4 sulfur cluster binding
V1	1902600	biological_process	proton transmembrane transport
V2	0003954	molecular_function	NADH dehydrogenase activity
V2	0005739	cellular_component	mitochondrion
V2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
V2	0016491	molecular_function	oxidoreductase activity
V2	0046872	molecular_function	metal ion binding
V2	0051536	molecular_function	iron-sulfur cluster binding
V2	0051537	molecular_function	2 iron, 2 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	binding site for residue NAP A9 401

Chain	Residue
A9	THR71
A9	TYR148
A9	MET157
A9	VAL177
A9	SER178
A9	CYS179
A9	LYS194
A9	ALA214
A9	ARG222
S7	LYS213
A9	GLY72
A9	PHE73
A9	LEU74
A9	ARG94
A9	LEU138
A9	ILE139
A9	GLY140
A9	ARG141

site_id	AC2
Number of Residues	4
Details	binding site for residue PC1 AL 401

Chain	Residue
AL	ARG31
S7	LEU70
S7	TRP73
S7	ARG76

site_id	AC3
Number of Residues	8
Details	binding site for residue SF4 S1 801

Chain	Residue
S1	HIS167
S1	CYS171
S1	CYS174
S1	GLY177
S1	CYS180
S1	VAL271
S1	GLY272
S2	ILE310

site_id	AC4
Number of Residues	10
Details	binding site for residue SF4 S1 802

Chain	Residue
S1	ARG218
S1	CYS219
S1	ILE220
S1	GLN221
S1	CYS222
S1	CYS225
S1	CYS269
S1	PRO270
S1	VAL271
S1	ALA273

site_id	AC5
Number of Residues	7
Details	binding site for residue FES S1 803

Chain	Residue
S1	CYS107
S1	TYR108
S1	GLY116
S1	CYS118
S1	ARG119
S1	CYS121
S1	CYS135

site_id	AC6
Number of Residues	11
Details	binding site for residue PC1 S2 401

Chain	Residue
1M	MET189
1M	ILE192
1M	VAL283
1M	TYR290
1M	LEU298
1M	VAL302
S2	ARG197
S2	GLN201
S8	THR70
S8	LEU71
S8	PHE72

site_id	AC7
Number of Residues	5
Details	binding site for residue ZN S6 300

Chain	Residue
S6	CYS65
S6	HIS75
S6	CYS90
S6	TYR92
S6	CYS93

site_id	AC8
Number of Residues	9
Details	binding site for residue SF4 S7 301

Chain	Residue
S2	ARG69
S7	ALA87
S7	CYS88
S7	CYS89
S7	GLY124
S7	THR125
S7	CYS153
S7	TYR160
S7	CYS183

site_id	AC9
Number of Residues	10
Details	binding site for residue SF4 S8 301

Chain	Residue
S8	HIS111
S8	CYS133
S8	PRO134
S8	ILE138
S8	CYS162
S8	ILE163
S8	CYS165
S8	PHE167
S8	CYS168
S8	GLU179

site_id	AD1
Number of Residues	9
Details	binding site for residue SF4 S8 302

Chain	Residue
S8	CYS123
S8	ILE124
S8	ALA125
S8	CYS126
S8	LYS127
S8	CYS129
S8	CYS172
S8	ALA176
S8	ILE177

site_id	AD2
Number of Residues	11
Details	binding site for residue SF4 V1 500

Chain	Residue
V1	ILE452
V1	CYS453
V1	LEU455
V1	ILE233
V1	PRO251
V1	SER406
V1	CYS407
V1	GLY408
V1	CYS410
V1	CYS413
V1	THR451

site_id	AD3
Number of Residues	15
Details	binding site for residue FMN V1 501

Chain	Residue
V1	GLY115
V1	ARG116
V1	GLY117
V1	LYS126
V1	ASN144
V1	ASP146
V1	GLU147
V1	SER148
V1	TYR232
V1	GLY235
V1	GLU236
V1	THR271
V1	ASN272
V1	ALA454
V1	LEU455

site_id	AD4
Number of Residues	6
Details	binding site for residue FES V2 300

Chain	Residue
V2	CYS126
V2	THR128
V2	CYS131
V2	CYS167
V2	GLY169
V2	CYS171

site_id	AD5
Number of Residues	6
Details	binding site for residue PC1 A1 101

Chain	Residue
1M	PHE46
A1	ASN2
A1	LEU3
A1	ARG4
A1	MET6
AL	ILE43

site_id	AD6
Number of Residues	8
Details	binding site for residue PC1 C2 101

Chain	Residue
C2	HIS31
C2	TRP33
C2	GLU34
G1	ARG24
G1	ARG28
G1	PC1701
G1	PC1702
L2	TYR238

site_id	AD7
Number of Residues	8
Details	binding site for residue PC1 G1 701

Chain	Residue
C2	PC1101
G1	LEU25
G1	ARG28
G1	TYR33
G1	PC1702
P2	ALA88
X1	TYR49
X1	ILE53

site_id	AD8
Number of Residues	8
Details	binding site for residue PC1 G1 702

Chain	Residue
2M	TRP45
C2	PC1101
G1	GLN36
G1	PC1701
G2	LYS229
G2	LYS233
X1	LEU50
X1	LYS54

site_id	AD9
Number of Residues	4
Details	binding site for residue ZN G1 703

Chain	Residue
G1	HIS130
G1	TYR207
G2	HIS107
G2	HIS135

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaICP

Chain	Residue	Details
S8	CYS123-PRO134
S8	CYS162-PRO173

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
S2	LEU47-LYS58

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREvwDMFgvssinHpdlRrIL

Chain	Residue	Details
S3	GLU112-LEU133

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYhsrlsiaGnCRmC

Chain	Residue	Details
S1	PRO104-CYS121

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
S1	CYS171-GLN183

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCVrF

Chain	Residue	Details
S1	ARG218-PHE228

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALLES

Chain	Residue	Details
V1	GLY228-SER243

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
V1	GLU405-GLY416

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpLaDGLKLIlKE

Chain	Residue	Details
1M	GLY47-GLU62

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLPEAEa.ESvaG

Chain	Residue	Details
1M	PRO202-GLY215

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DglFSvgemeCMGcCvnAP

Chain	Residue	Details
V2	ASP157-PRO175

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP

Chain	Residue	Details
S7	GLY169-PRO185

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)