6X7R
E. coli beta-ketoacyl-[acyl carrier protein] synthase III (FabH) in complex with oxa(dethia)-coenzyme A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0030497 | biological_process | fatty acid elongation |
| A | 0033818 | molecular_function | beta-ketoacyl-acyl-carrier-protein synthase III activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | binding site for residue UT7 A 401 |
| Chain | Residue |
| A | THR28 |
| A | MET207 |
| A | GLY209 |
| A | ASN210 |
| A | VAL212 |
| A | HIS244 |
| A | ASN247 |
| A | ARG249 |
| A | ILE250 |
| A | ASN274 |
| A | PHE304 |
| A | TRP32 |
| A | HOH503 |
| A | HOH526 |
| A | HOH529 |
| A | HOH535 |
| A | HOH549 |
| A | HOH566 |
| A | HOH570 |
| A | HOH631 |
| A | HOH667 |
| A | HOH686 |
| A | ARG36 |
| A | HOH700 |
| A | HOH706 |
| A | HOH727 |
| A | HOH743 |
| A | HOH775 |
| A | THR37 |
| A | CYS112 |
| A | ARG151 |
| A | ILE155 |
| A | ILE156 |
| A | LEU189 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | HOH570 |
| A | HOH695 |
| A | HOH836 |
| A | HOH847 |
| A | HOH861 |
| A | HOH867 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 403 |
| Chain | Residue |
| A | HIS178 |
| A | LEU179 |
| A | HOH555 |
| A | HOH603 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Region: {"description":"ACP-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_01815","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01815","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10593943","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"10673437","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"11243824","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
