6X71

Rev1 Mg2+-facilitated Intermediate complex with reactant dCTP and product dCMP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue GOL P 101

Chain	Residue
A	ARG324
A	ASP399
A	HOH1019
P	DG12
P	DC13
P	DCP106
P	HOH212
P	HOH215
P	HOH226

---

site_id	AC2
Number of Residues	8
Details	binding site for residue MG P 102

Chain	Residue
A	ASP362
A	ASP467
A	GLU468
A	HOH1170
P	DG12
P	DC13
P	MG103
P	DCP106

---

site_id	AC3
Number of Residues	7
Details	binding site for residue MG P 103

Chain	Residue
A	ASP362
A	PHE363
A	ASP467
P	DC13
P	MG102
P	DCP106
P	POP107

---

site_id	AC4
Number of Residues	6
Details	binding site for residue MG P 104

Chain	Residue
A	ASP362
A	ARG518
A	HOH1102
A	HOH1170
P	DCP106
P	POP107

---

site_id	AC5
Number of Residues	6
Details	binding site for residue MG P 105

Chain	Residue
A	ASP548
A	LEU550
A	VAL553
A	HOH932
A	HOH1163
P	DA11

---

site_id	AC6
Number of Residues	26
Details	binding site for residue DCP P 106

Chain	Residue
A	ARG324
A	ASP362
A	PHE363
A	ASP364
A	CYS365
A	PHE366
A	PHE367
A	ALA401
A	SER402
A	TYR405
A	ARG408
A	ASN414
A	ASP467
A	LYS525
A	HOH1170
P	DG12
P	DC13
P	GOL101
P	MG102
P	MG103
P	MG104
P	POP107
P	HOH205
P	HOH209
P	HOH217
P	HOH229

---

site_id	AC7
Number of Residues	17
Details	binding site for residue POP P 107

Chain	Residue
A	ASP362
A	PHE363
A	ASP364
A	CYS365
A	PHE366
A	SER402
A	TYR405
A	ARG408
A	ASN414
A	ASP467
A	LYS525
P	DC13
P	MG103
P	MG104
P	DCP106
P	HOH205
P	HOH209

---

site_id	AC8
Number of Residues	11
Details	binding site for residue GOL A 801

Chain	Residue
A	TRP331
A	ASN334
A	LEU335
A	GLN442
A	SER445
A	GLU446
A	ILE466
A	HOH907
A	HOH922
A	HOH963
A	HOH975

---

site_id	AC9
Number of Residues	8
Details	binding site for residue GOL A 802

Chain	Residue
A	LEU335
A	LYS338
A	GLU342
A	TYR449
A	PRO463
A	HOH909
A	HOH963
A	HOH1098

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:16195463, ECO:0000269|PubMed:18275815

Chain	Residue	Details
A	ASN414
A	ARG324
A	SER402

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00216, ECO:0000269|PubMed:18275815

Chain	Residue	Details
A	PHE363
A	ASP467
A	GLU468
A	ASP362

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	SITE: Interaction with target DNA

Chain	Residue	Details
A	SER692
A	SER694
A	LYS681

---