Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | GLU8 |
| A | ASP92 |
| A | CYS195 |
| A | ASN198 |
| A | HOH432 |
| A | HOH553 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 302 |
| Chain | Residue |
| A | HOH449 |
| A | HOH539 |
| A | HOH580 |
| A | HIS141 |
| A | HIS145 |
| A | HIS151 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue PG4 A 303 |
| Chain | Residue |
| A | SER90 |
| A | ASP153 |
| A | THR154 |
| A | CYS155 |
| A | SER156 |
| A | GLN194 |
| A | HOH441 |
| A | HOH492 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ASN24 |
| A | ASP24 |
| A | ARG109 |
| A | ARG111 |
| A | HOH401 |
| A | HOH447 |
| A | HOH497 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | SER129 |
| A | LYS130 |
| A | ASN131 |
| A | TRP134 |
| A | LYS170 |
| A | THR186 |
| A | HOH430 |
| A | HOH520 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TMAHELGHNL |
| Chain | Residue | Details |
| A | THR138-LEU147 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 195 |
| Details | Domain: {"description":"Peptidase M12B","evidences":[{"source":"PROSITE-ProRule","id":"PRU00276","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00276","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32946987","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6X5X","evidenceCode":"ECO:0007744"}]} |
