6X5T

Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP and A3-Asn

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0001701	biological_process	in utero embryonic development
A	0005515	molecular_function	protein binding
A	0005794	cellular_component	Golgi apparatus
A	0006486	biological_process	obsolete protein glycosylation
A	0006487	biological_process	protein N-linked glycosylation
A	0006491	biological_process	N-glycan processing
A	0008424	molecular_function	glycoprotein 6-alpha-L-fucosyltransferase activity
A	0009101	biological_process	glycoprotein biosynthetic process
A	0009312	biological_process	oligosaccharide biosynthetic process
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0017124	molecular_function	SH3 domain binding
A	0019082	biological_process	viral protein processing
A	0032580	cellular_component	Golgi cisterna membrane
A	0036066	biological_process	protein O-linked glycosylation via fucose
A	0042355	biological_process	L-fucose catabolic process
A	0046368	biological_process	GDP-L-fucose metabolic process
A	0046921	molecular_function	alpha-(1->6)-fucosyltransferase activity
A	0070062	cellular_component	extracellular exosome
B	0000139	cellular_component	Golgi membrane
B	0001701	biological_process	in utero embryonic development
B	0005515	molecular_function	protein binding
B	0005794	cellular_component	Golgi apparatus
B	0006486	biological_process	obsolete protein glycosylation
B	0006487	biological_process	protein N-linked glycosylation
B	0006491	biological_process	N-glycan processing
B	0008424	molecular_function	glycoprotein 6-alpha-L-fucosyltransferase activity
B	0009101	biological_process	glycoprotein biosynthetic process
B	0009312	biological_process	oligosaccharide biosynthetic process
B	0016020	cellular_component	membrane
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0017124	molecular_function	SH3 domain binding
B	0019082	biological_process	viral protein processing
B	0032580	cellular_component	Golgi cisterna membrane
B	0036066	biological_process	protein O-linked glycosylation via fucose
B	0042355	biological_process	L-fucose catabolic process
B	0046368	biological_process	GDP-L-fucose metabolic process
B	0046921	molecular_function	alpha-(1->6)-fucosyltransferase activity
B	0070062	cellular_component	extracellular exosome
C	0000139	cellular_component	Golgi membrane
C	0001701	biological_process	in utero embryonic development
C	0005515	molecular_function	protein binding
C	0005794	cellular_component	Golgi apparatus
C	0006486	biological_process	obsolete protein glycosylation
C	0006487	biological_process	protein N-linked glycosylation
C	0006491	biological_process	N-glycan processing
C	0008424	molecular_function	glycoprotein 6-alpha-L-fucosyltransferase activity
C	0009101	biological_process	glycoprotein biosynthetic process
C	0009312	biological_process	oligosaccharide biosynthetic process
C	0016020	cellular_component	membrane
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0017124	molecular_function	SH3 domain binding
C	0019082	biological_process	viral protein processing
C	0032580	cellular_component	Golgi cisterna membrane
C	0036066	biological_process	protein O-linked glycosylation via fucose
C	0042355	biological_process	L-fucose catabolic process
C	0046368	biological_process	GDP-L-fucose metabolic process
C	0046921	molecular_function	alpha-(1->6)-fucosyltransferase activity
C	0070062	cellular_component	extracellular exosome
D	0000139	cellular_component	Golgi membrane
D	0001701	biological_process	in utero embryonic development
D	0005515	molecular_function	protein binding
D	0005794	cellular_component	Golgi apparatus
D	0006486	biological_process	obsolete protein glycosylation
D	0006487	biological_process	protein N-linked glycosylation
D	0006491	biological_process	N-glycan processing
D	0008424	molecular_function	glycoprotein 6-alpha-L-fucosyltransferase activity
D	0009101	biological_process	glycoprotein biosynthetic process
D	0009312	biological_process	oligosaccharide biosynthetic process
D	0016020	cellular_component	membrane
D	0016740	molecular_function	transferase activity
D	0016757	molecular_function	glycosyltransferase activity
D	0017124	molecular_function	SH3 domain binding
D	0019082	biological_process	viral protein processing
D	0032580	cellular_component	Golgi cisterna membrane
D	0036066	biological_process	protein O-linked glycosylation via fucose
D	0042355	biological_process	L-fucose catabolic process
D	0046368	biological_process	GDP-L-fucose metabolic process
D	0046921	molecular_function	alpha-(1->6)-fucosyltransferase activity
D	0070062	cellular_component	extracellular exosome
E	0000139	cellular_component	Golgi membrane
E	0001701	biological_process	in utero embryonic development
E	0005515	molecular_function	protein binding
E	0005794	cellular_component	Golgi apparatus
E	0006486	biological_process	obsolete protein glycosylation
E	0006487	biological_process	protein N-linked glycosylation
E	0006491	biological_process	N-glycan processing
E	0008424	molecular_function	glycoprotein 6-alpha-L-fucosyltransferase activity
E	0009101	biological_process	glycoprotein biosynthetic process
E	0009312	biological_process	oligosaccharide biosynthetic process
E	0016020	cellular_component	membrane
E	0016740	molecular_function	transferase activity
E	0016757	molecular_function	glycosyltransferase activity
E	0017124	molecular_function	SH3 domain binding
E	0019082	biological_process	viral protein processing
E	0032580	cellular_component	Golgi cisterna membrane
E	0036066	biological_process	protein O-linked glycosylation via fucose
E	0042355	biological_process	L-fucose catabolic process
E	0046368	biological_process	GDP-L-fucose metabolic process
E	0046921	molecular_function	alpha-(1->6)-fucosyltransferase activity
E	0070062	cellular_component	extracellular exosome
F	0000139	cellular_component	Golgi membrane
F	0001701	biological_process	in utero embryonic development
F	0005515	molecular_function	protein binding
F	0005794	cellular_component	Golgi apparatus
F	0006486	biological_process	obsolete protein glycosylation
F	0006487	biological_process	protein N-linked glycosylation
F	0006491	biological_process	N-glycan processing
F	0008424	molecular_function	glycoprotein 6-alpha-L-fucosyltransferase activity
F	0009101	biological_process	glycoprotein biosynthetic process
F	0009312	biological_process	oligosaccharide biosynthetic process
F	0016020	cellular_component	membrane
F	0016740	molecular_function	transferase activity
F	0016757	molecular_function	glycosyltransferase activity
F	0017124	molecular_function	SH3 domain binding
F	0019082	biological_process	viral protein processing
F	0032580	cellular_component	Golgi cisterna membrane
F	0036066	biological_process	protein O-linked glycosylation via fucose
F	0042355	biological_process	L-fucose catabolic process
F	0046368	biological_process	GDP-L-fucose metabolic process
F	0046921	molecular_function	alpha-(1->6)-fucosyltransferase activity
F	0070062	cellular_component	extracellular exosome
G	0000139	cellular_component	Golgi membrane
G	0001701	biological_process	in utero embryonic development
G	0005515	molecular_function	protein binding
G	0005794	cellular_component	Golgi apparatus
G	0006486	biological_process	obsolete protein glycosylation
G	0006487	biological_process	protein N-linked glycosylation
G	0006491	biological_process	N-glycan processing
G	0008424	molecular_function	glycoprotein 6-alpha-L-fucosyltransferase activity
G	0009101	biological_process	glycoprotein biosynthetic process
G	0009312	biological_process	oligosaccharide biosynthetic process
G	0016020	cellular_component	membrane
G	0016740	molecular_function	transferase activity
G	0016757	molecular_function	glycosyltransferase activity
G	0017124	molecular_function	SH3 domain binding
G	0019082	biological_process	viral protein processing
G	0032580	cellular_component	Golgi cisterna membrane
G	0036066	biological_process	protein O-linked glycosylation via fucose
G	0042355	biological_process	L-fucose catabolic process
G	0046368	biological_process	GDP-L-fucose metabolic process
G	0046921	molecular_function	alpha-(1->6)-fucosyltransferase activity
G	0070062	cellular_component	extracellular exosome
H	0000139	cellular_component	Golgi membrane
H	0001701	biological_process	in utero embryonic development
H	0005515	molecular_function	protein binding
H	0005794	cellular_component	Golgi apparatus
H	0006486	biological_process	obsolete protein glycosylation
H	0006487	biological_process	protein N-linked glycosylation
H	0006491	biological_process	N-glycan processing
H	0008424	molecular_function	glycoprotein 6-alpha-L-fucosyltransferase activity
H	0009101	biological_process	glycoprotein biosynthetic process
H	0009312	biological_process	oligosaccharide biosynthetic process
H	0016020	cellular_component	membrane
H	0016740	molecular_function	transferase activity
H	0016757	molecular_function	glycosyltransferase activity
H	0017124	molecular_function	SH3 domain binding
H	0019082	biological_process	viral protein processing
H	0032580	cellular_component	Golgi cisterna membrane
H	0036066	biological_process	protein O-linked glycosylation via fucose
H	0042355	biological_process	L-fucose catabolic process
H	0046368	biological_process	GDP-L-fucose metabolic process
H	0046921	molecular_function	alpha-(1->6)-fucosyltransferase activity
H	0070062	cellular_component	extracellular exosome

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2296
Details	Domain: {"description":"GT23","evidences":[{"source":"PROSITE-ProRule","id":"PRU00992","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	488
Details	Domain: {"description":"SH3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00192","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Region: {"description":"Important for donor substrate binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	48
Details	Motif: {"description":"SH3-binding","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9WTS2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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