6WYM
Transition metal inhibition and structural refinement of the M. tuberculosis esterase, Rv0045c
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 401 |
| Chain | Residue |
| A | GLY90 |
| A | SER154 |
| A | LEU155 |
| A | HOH635 |
| A | HOH694 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000305|PubMed:21637775, ECO:0000305|PubMed:25354081 |
| Chain | Residue | Details |
| A | SER154 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:25354081 |
| Chain | Residue | Details |
| A | ASP178 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:21637775, ECO:0000305|PubMed:25354081 |
| Chain | Residue | Details |
| A | HIS309 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Involved in substrate selectivity => ECO:0000269|PubMed:25354081 |
| Chain | Residue | Details |
| A | GLY90 | |
| A | HIS187 |
