6WWD

Crystal structure of Nucleoside-triphosphatase / dITP/XTP pyrophosphatase from Mycobacterium abscessus ATCC 19977 / DSM 44196

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0009117	biological_process	nucleotide metabolic process
A	0009143	biological_process	nucleoside triphosphate catabolic process
A	0009146	biological_process	purine nucleoside triphosphate catabolic process
A	0016787	molecular_function	hydrolase activity
A	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
A	0035870	molecular_function	dITP diphosphatase activity
A	0036220	molecular_function	ITP diphosphatase activity
A	0036222	molecular_function	XTP diphosphatase activity
A	0046872	molecular_function	metal ion binding
A	0047429	molecular_function	nucleoside triphosphate diphosphatase activity
B	0000166	molecular_function	nucleotide binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0009117	biological_process	nucleotide metabolic process
B	0009143	biological_process	nucleoside triphosphate catabolic process
B	0009146	biological_process	purine nucleoside triphosphate catabolic process
B	0016787	molecular_function	hydrolase activity
B	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
B	0035870	molecular_function	dITP diphosphatase activity
B	0036220	molecular_function	ITP diphosphatase activity
B	0036222	molecular_function	XTP diphosphatase activity
B	0046872	molecular_function	metal ion binding
B	0047429	molecular_function	nucleoside triphosphate diphosphatase activity
C	0000166	molecular_function	nucleotide binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0009117	biological_process	nucleotide metabolic process
C	0009143	biological_process	nucleoside triphosphate catabolic process
C	0009146	biological_process	purine nucleoside triphosphate catabolic process
C	0016787	molecular_function	hydrolase activity
C	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
C	0035870	molecular_function	dITP diphosphatase activity
C	0036220	molecular_function	ITP diphosphatase activity
C	0036222	molecular_function	XTP diphosphatase activity
C	0046872	molecular_function	metal ion binding
C	0047429	molecular_function	nucleoside triphosphate diphosphatase activity
D	0000166	molecular_function	nucleotide binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0009117	biological_process	nucleotide metabolic process
D	0009143	biological_process	nucleoside triphosphate catabolic process
D	0009146	biological_process	purine nucleoside triphosphate catabolic process
D	0016787	molecular_function	hydrolase activity
D	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
D	0035870	molecular_function	dITP diphosphatase activity
D	0036220	molecular_function	ITP diphosphatase activity
D	0036222	molecular_function	XTP diphosphatase activity
D	0046872	molecular_function	metal ion binding
D	0047429	molecular_function	nucleoside triphosphate diphosphatase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_01405

Chain	Residue	Details
A	ASP72
B	ASP72
C	ASP72
D	ASP72

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site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01405

Chain	Residue	Details
A	SER7
B	PHE155
B	LYS178
B	HIS183
C	SER7
C	ASP72
C	SER73
C	PHE155
C	LYS178
C	HIS183
D	SER7
A	ASP72
D	ASP72
D	SER73
D	PHE155
D	LYS178
D	HIS183
A	SER73
A	PHE155
A	LYS178
A	HIS183
B	SER7
B	ASP72
B	SER73

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