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6WVK

Cryo-EM structure of Bacillus subtilis RNA Polymerase in complex with HelD

Functional Information from GO Data
ChainGOidnamespacecontents
A0000428cellular_componentDNA-directed RNA polymerase complex
A0003677molecular_functionDNA binding
A0003899molecular_functionDNA-directed RNA polymerase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0006351biological_processDNA-templated transcription
A0016740molecular_functiontransferase activity
A0016779molecular_functionnucleotidyltransferase activity
A0034062molecular_function5'-3' RNA polymerase activity
A0046983molecular_functionprotein dimerization activity
B0000428cellular_componentDNA-directed RNA polymerase complex
B0003677molecular_functionDNA binding
B0003899molecular_functionDNA-directed RNA polymerase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0006351biological_processDNA-templated transcription
B0016740molecular_functiontransferase activity
B0016779molecular_functionnucleotidyltransferase activity
B0034062molecular_function5'-3' RNA polymerase activity
B0046983molecular_functionprotein dimerization activity
C0000345cellular_componentcytosolic DNA-directed RNA polymerase complex
C0000428cellular_componentDNA-directed RNA polymerase complex
C0003677molecular_functionDNA binding
C0003899molecular_functionDNA-directed RNA polymerase activity
C0006351biological_processDNA-templated transcription
C0006352biological_processDNA-templated transcription initiation
C0006354biological_processDNA-templated transcription elongation
C0016740molecular_functiontransferase activity
C0016779molecular_functionnucleotidyltransferase activity
C0032549molecular_functionribonucleoside binding
C0034062molecular_function5'-3' RNA polymerase activity
C0046677biological_processresponse to antibiotic
D0000287molecular_functionmagnesium ion binding
D0000428cellular_componentDNA-directed RNA polymerase complex
D0003677molecular_functionDNA binding
D0003899molecular_functionDNA-directed RNA polymerase activity
D0005515molecular_functionprotein binding
D0005829cellular_componentcytosol
D0006351biological_processDNA-templated transcription
D0008270molecular_functionzinc ion binding
D0016740molecular_functiontransferase activity
D0016779molecular_functionnucleotidyltransferase activity
D0034062molecular_function5'-3' RNA polymerase activity
D0046677biological_processresponse to antibiotic
D0046872molecular_functionmetal ion binding
E0000428cellular_componentDNA-directed RNA polymerase complex
E0003677molecular_functionDNA binding
E0003899molecular_functionDNA-directed RNA polymerase activity
E0006351biological_processDNA-templated transcription
E0009295cellular_componentnucleoid
E0016740molecular_functiontransferase activity
E0016779molecular_functionnucleotidyltransferase activity
F0000345cellular_componentcytosolic DNA-directed RNA polymerase complex
F0000428cellular_componentDNA-directed RNA polymerase complex
F0001000molecular_functionbacterial-type RNA polymerase core enzyme binding
F0003677molecular_functionDNA binding
F0003899molecular_functionDNA-directed RNA polymerase activity
F0006351biological_processDNA-templated transcription
F0006352biological_processDNA-templated transcription initiation
F0016740molecular_functiontransferase activity
F0016779molecular_functionnucleotidyltransferase activity
F0034062molecular_function5'-3' RNA polymerase activity
H0000166molecular_functionnucleotide binding
H0000725biological_processrecombinational repair
H0003677molecular_functionDNA binding
H0003678molecular_functionDNA helicase activity
H0003711molecular_functiontranscription elongation factor activity
H0005524molecular_functionATP binding
H0005737cellular_componentcytoplasm
H0005829cellular_componentcytosol
H0006351biological_processDNA-templated transcription
H0016787molecular_functionhydrolase activity
H0043138molecular_function3'-5' DNA helicase activity
H0043139molecular_function5'-3' DNA helicase activity
Functional Information from PROSITE/UniProt
site_idPS01166
Number of Residues13
DetailsRNA_POL_BETA RNA polymerases beta chain signature. GdKMAGrHGNKGV
ChainResidueDetails
CGLY922-VAL934

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues11
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues398
DetailsDomain: {"description":"UvrD-like helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00560","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues12
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00560","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

247947

PDB entries from 2026-01-21

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