6WV8
Takifugu rubripes VKOR-like C138S mutant with vitamin K1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0006091 | biological_process | generation of precursor metabolites and energy |
| A | 0008218 | biological_process | bioluminescence |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016728 | molecular_function | oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor |
| A | 0042373 | biological_process | vitamin K metabolic process |
| A | 0047057 | molecular_function | vitamin-K-epoxide reductase (warfarin-sensitive) activity |
| A | 0048038 | molecular_function | quinone binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue PQN A 501 |
| Chain | Residue |
| A | VAL199 |
| A | ILE268 |
| A | CYS280 |
| A | THR283 |
| A | TYR284 |
| A | GLY205 |
| A | PHE208 |
| A | ASN225 |
| A | GLY229 |
| A | PHE232 |
| A | THR254 |
| A | SER258 |
| A | LEU265 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"(Z)-2,3-didehydrotyrosine","evidences":[{"source":"PubMed","id":"8448132","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"5-imidazolinone (Ser-Gly)","evidences":[{"source":"PubMed","id":"8448132","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 84 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"33154105","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WV8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 52 |
| Details | Topological domain: {"description":"Lumenal","evidences":[{"source":"PubMed","id":"33154105","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WV8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"33154105","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WV8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33154105","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WVB","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33154105","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
