Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6WU6

succinate-coenzyme Q reductase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006099	biological_process	tricarboxylic acid cycle
A	0016491	molecular_function	oxidoreductase activity
A	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
A	0022900	biological_process	electron transport chain
A	0050660	molecular_function	flavin adenine dinucleotide binding
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006099	biological_process	tricarboxylic acid cycle
B	0008177	molecular_function	succinate dehydrogenase (quinone) activity
B	0009055	molecular_function	electron transfer activity
B	0009060	biological_process	aerobic respiration
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0019646	biological_process	aerobic electron transport chain
B	0022904	biological_process	respiratory electron transport chain
B	0046872	molecular_function	metal ion binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051537	molecular_function	2 iron, 2 sulfur cluster binding
B	0051538	molecular_function	3 iron, 4 sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0005886	cellular_component	plasma membrane
C	0006099	biological_process	tricarboxylic acid cycle
C	0008177	molecular_function	succinate dehydrogenase (quinone) activity
C	0009055	molecular_function	electron transfer activity
C	0009060	biological_process	aerobic respiration
C	0016020	cellular_component	membrane
C	0017004	biological_process	cytochrome complex assembly
C	0019646	biological_process	aerobic electron transport chain
C	0020037	molecular_function	heme binding
C	0046872	molecular_function	metal ion binding
C	0048039	molecular_function	ubiquinone binding
D	0006099	biological_process	tricarboxylic acid cycle
D	0016020	cellular_component	membrane
D	0020037	molecular_function	heme binding
E	0006099	biological_process	tricarboxylic acid cycle
E	0016491	molecular_function	oxidoreductase activity
E	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
E	0022900	biological_process	electron transport chain
E	0050660	molecular_function	flavin adenine dinucleotide binding
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0006099	biological_process	tricarboxylic acid cycle
F	0008177	molecular_function	succinate dehydrogenase (quinone) activity
F	0009055	molecular_function	electron transfer activity
F	0009060	biological_process	aerobic respiration
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0019646	biological_process	aerobic electron transport chain
F	0022904	biological_process	respiratory electron transport chain
F	0046872	molecular_function	metal ion binding
F	0051536	molecular_function	iron-sulfur cluster binding
F	0051537	molecular_function	2 iron, 2 sulfur cluster binding
F	0051538	molecular_function	3 iron, 4 sulfur cluster binding
F	0051539	molecular_function	4 iron, 4 sulfur cluster binding
G	0005886	cellular_component	plasma membrane
G	0006099	biological_process	tricarboxylic acid cycle
G	0008177	molecular_function	succinate dehydrogenase (quinone) activity
G	0009055	molecular_function	electron transfer activity
G	0009060	biological_process	aerobic respiration
G	0016020	cellular_component	membrane
G	0017004	biological_process	cytochrome complex assembly
G	0019646	biological_process	aerobic electron transport chain
G	0020037	molecular_function	heme binding
G	0046872	molecular_function	metal ion binding
G	0048039	molecular_function	ubiquinone binding
H	0006099	biological_process	tricarboxylic acid cycle
H	0016020	cellular_component	membrane
H	0020037	molecular_function	heme binding
I	0006099	biological_process	tricarboxylic acid cycle
I	0016491	molecular_function	oxidoreductase activity
I	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
I	0022900	biological_process	electron transport chain
I	0050660	molecular_function	flavin adenine dinucleotide binding
J	0005515	molecular_function	protein binding
J	0005886	cellular_component	plasma membrane
J	0006099	biological_process	tricarboxylic acid cycle
J	0008177	molecular_function	succinate dehydrogenase (quinone) activity
J	0009055	molecular_function	electron transfer activity
J	0009060	biological_process	aerobic respiration
J	0016020	cellular_component	membrane
J	0016491	molecular_function	oxidoreductase activity
J	0019646	biological_process	aerobic electron transport chain
J	0022904	biological_process	respiratory electron transport chain
J	0046872	molecular_function	metal ion binding
J	0051536	molecular_function	iron-sulfur cluster binding
J	0051537	molecular_function	2 iron, 2 sulfur cluster binding
J	0051538	molecular_function	3 iron, 4 sulfur cluster binding
J	0051539	molecular_function	4 iron, 4 sulfur cluster binding
K	0005886	cellular_component	plasma membrane
K	0006099	biological_process	tricarboxylic acid cycle
K	0008177	molecular_function	succinate dehydrogenase (quinone) activity
K	0009055	molecular_function	electron transfer activity
K	0009060	biological_process	aerobic respiration
K	0016020	cellular_component	membrane
K	0017004	biological_process	cytochrome complex assembly
K	0019646	biological_process	aerobic electron transport chain
K	0020037	molecular_function	heme binding
K	0046872	molecular_function	metal ion binding
K	0048039	molecular_function	ubiquinone binding
L	0006099	biological_process	tricarboxylic acid cycle
L	0016020	cellular_component	membrane
L	0020037	molecular_function	heme binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue FES B 301

Chain	Residue
B	SER54
B	CYS75
B	CYS55
B	ARG56
B	GLY58
B	VAL59
B	CYS60
B	GLY61
B	SER62
B	ASP63

site_id	AC2
Number of Residues	8
Details	binding site for residue SF4 B 302

Chain	Residue
B	CYS149
B	ILE150
B	CYS152
B	ALA153
B	CYS155
B	CYS216
B	PRO217
B	LEU220

site_id	AC3
Number of Residues	9
Details	binding site for residue F3S B 303

Chain	Residue
B	CYS159
B	SER161
B	PHE169
B	CYS206
B	SER208
B	ILE209
B	MET210
B	ASN211
B	CYS212

site_id	AC4
Number of Residues	9
Details	binding site for residue HEM C 201

Chain	Residue
C	HIS30
C	GLY34
C	HIS84
C	VAL85
D	ALA23
D	THR27
D	ILE30
D	HIS71
D	GLY75

site_id	AC5
Number of Residues	10
Details	binding site for residue FES F 301

Chain	Residue
F	SER54
F	CYS55
F	ARG56
F	GLY58
F	VAL59
F	CYS60
F	GLY61
F	SER62
F	ASP63
F	CYS75

site_id	AC6
Number of Residues	8
Details	binding site for residue SF4 F 302

Chain	Residue
F	CYS149
F	ILE150
F	CYS152
F	ALA153
F	CYS155
F	CYS216
F	PRO217
F	LEU220

site_id	AC7
Number of Residues	9
Details	binding site for residue F3S F 303

Chain	Residue
F	CYS159
F	SER161
F	PHE169
F	CYS206
F	SER208
F	ILE209
F	MET210
F	ASN211
F	CYS212

site_id	AC8
Number of Residues	9
Details	binding site for residue HEM G 201

Chain	Residue
G	HIS30
G	GLY34
G	HIS84
G	VAL85
H	ALA23
H	THR27
H	ILE30
H	HIS71
H	GLY75

site_id	AC9
Number of Residues	10
Details	binding site for residue FES J 301

Chain	Residue
J	SER54
J	CYS55
J	ARG56
J	GLY58
J	VAL59
J	CYS60
J	GLY61
J	SER62
J	ASP63
J	CYS75

site_id	AD1
Number of Residues	8
Details	binding site for residue SF4 J 302

Chain	Residue
J	CYS149
J	ILE150
J	CYS152
J	ALA153
J	CYS155
J	CYS216
J	PRO217
J	LEU220

site_id	AD2
Number of Residues	9
Details	binding site for residue F3S J 303

Chain	Residue
J	CYS159
J	SER161
J	PHE169
J	CYS206
J	SER208
J	ILE209
J	MET210
J	ASN211
J	CYS212

site_id	AD3
Number of Residues	9
Details	binding site for residue HEM K 201

Chain	Residue
K	HIS30
K	GLY34
K	HIS84
K	VAL85
L	ALA23
L	THR27
L	ILE30
L	HIS71
L	GLY75

site_id	AD4
Number of Residues	25
Details	binding site for residue FAD A 601

Chain	Residue
A	ILE13
A	GLY14
A	ALA15
A	GLY16
A	GLY17
A	ALA18
A	VAL39
A	SER44
A	THR46
A	SER48
A	ALA49
A	GLN50
A	TYR165
A	THR202
A	ILE217
A	THR219
A	ASP221
A	HIS354
A	GLU388
A	ARG399
A	GLY402
A	ASN403
A	SER404
A	LEU405
A	LEU408

site_id	AD5
Number of Residues	3
Details	binding site for residue NA A 602

Chain	Residue
A	MET356
A	GLY358
A	GLY359

site_id	AD6
Number of Residues	25
Details	binding site for residue FAD E 601

Chain	Residue
E	ILE13
E	GLY14
E	ALA15
E	GLY16
E	GLY17
E	ALA18
E	VAL39
E	SER44
E	THR46
E	SER48
E	ALA49
E	GLN50
E	TYR165
E	THR202
E	ILE217
E	THR219
E	ASP221
E	HIS354
E	GLU388
E	ARG399
E	GLY402
E	ASN403
E	SER404
E	LEU405
E	LEU408

site_id	AD7
Number of Residues	3
Details	binding site for residue NA E 602

Chain	Residue
E	MET356
E	GLY358
E	GLY359

site_id	AD8
Number of Residues	25
Details	binding site for residue FAD I 601

Chain	Residue
I	ILE13
I	GLY14
I	ALA15
I	GLY16
I	GLY17
I	ALA18
I	VAL39
I	SER44
I	THR46
I	SER48
I	ALA49
I	GLN50
I	TYR165
I	THR202
I	ILE217
I	THR219
I	ASP221
I	HIS354
I	GLU388
I	ARG399
I	GLY402
I	ASN403
I	SER404
I	LEU405
I	LEU408

site_id	AD9
Number of Residues	3
Details	binding site for residue NA I 602

Chain	Residue
I	MET356
I	GLY358
I	GLY359

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiLCAcCStSCP

Chain	Residue	Details
B	CYS149-PRO160

site_id	PS00504
Number of Residues	10
Details	FRD_SDH_FAD_BINDING Fumarate reductase / succinate dehydrogenase FAD-binding site. RSHTvsAqGG

Chain	Residue	Details
A	ARG43-GLY52

site_id	PS01000
Number of Residues	25
Details	SDH_CYT_1 Succinate dehydrogenase cytochrome b subunit signature 1. RPVnldLqtirfpItaiaSilHRvS

Chain	Residue	Details
C	ARG9-SER33

site_id	PS01001
Number of Residues	14
Details	SDH_CYT_2 Succinate dehydrogenase cytochrome b subunit signature 2. HvvvGIRHMmMDfG

Chain	Residue	Details
C	HIS84-GLY97

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	267
Details	Domain: {"description":"2Fe-2S ferredoxin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00465","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	90
Details	Domain: {"description":"4Fe-4S ferredoxin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	30
Details	Binding site: {}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12560550","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	3
Details	Binding site: {"description":"axial binding residue"}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	195
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	45
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"15919996","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	54
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"15919996","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)