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6WTC

Crystal Structure of the Second Form of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2

Functional Information from GO Data
ChainGOidnamespacecontents
A0004197molecular_functioncysteine-type endopeptidase activity
A0008242molecular_functionomega peptidase activity
A0016740molecular_functiontransferase activity
B0004197molecular_functioncysteine-type endopeptidase activity
B0008242molecular_functionomega peptidase activity
B0016740molecular_functiontransferase activity
C0004197molecular_functioncysteine-type endopeptidase activity
C0008242molecular_functionomega peptidase activity
C0016740molecular_functiontransferase activity
D0004197molecular_functioncysteine-type endopeptidase activity
D0008242molecular_functionomega peptidase activity
D0016740molecular_functiontransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues3
Detailsbinding site for residue ACY B 201
ChainResidue
AVAL53
BALA150
BARG190

site_idAC2
Number of Residues3
Detailsbinding site for residue ACY C 301
ChainResidue
CARG21
DASP78
DARG80

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSITE: Cleavage; by 3CL-PRO => ECO:0000250|UniProtKB:P0C6V3
ChainResidueDetails
BGLN198
DGLN198

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PDB entries from 2025-06-11

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