6WRH
The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 501 |
| Chain | Residue |
| A | CYS189 |
| A | CYS192 |
| A | CYS224 |
| A | CYS226 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue PO4 A 502 |
| Chain | Residue |
| A | GLY271 |
| A | HIS272 |
| A | HOH692 |
| A | HOH751 |
| A | HOH884 |
| A | TRP106 |
| A | ASN109 |
| A | ASN110 |
| A | SER111 |
| A | LYS228 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 503 |
| Chain | Residue |
| A | GLU1 |
| A | HIS47 |
| A | SER49 |
| A | HOH616 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 A 504 |
| Chain | Residue |
| A | HIS73 |
| A | ASN128 |
| A | PRO129 |
| A | GLN174 |
| A | HIS175 |
| A | GLU203 |
| A | HOH637 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 505 |
| Chain | Residue |
| A | PHE127 |
| A | HOH708 |
| A | HOH901 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 506 |
| Chain | Residue |
| A | THR10 |
| A | VAL11 |
| A | ASP12 |
| A | ASN15 |
| A | GLU67 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 507 |
| Chain | Residue |
| A | SER85 |
| A | ASN88 |
| A | HIS89 |
| A | HOH636 |
| A | HOH790 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 508 |
| Chain | Residue |
| A | ARG65 |
| A | ASP164 |
| A | TYR264 |
| A | TYR273 |
| A | THR301 |
| A | HOH611 |
| A | HOH642 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 55 |
| Details | Domain: {"description":"Ubiquitin-like 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00214","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Repeat: {"description":"LRR 3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 37 |
| Details | Zinc finger: {"description":"C4-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00444","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For PL-PRO activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00444","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"32726803","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For PL-PRO activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00444","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00444","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
