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6WOV

Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 wild type in complex with FKBP12.6

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0001666biological_processresponse to hypoxia
A0002027biological_processregulation of heart rate
A0003143biological_processembryonic heart tube morphogenesis
A0003220biological_processleft ventricular cardiac muscle tissue morphogenesis
A0003300biological_processcardiac muscle hypertrophy
A0005216molecular_functionmonoatomic ion channel activity
A0005219molecular_functionryanodine-sensitive calcium-release channel activity
A0005262molecular_functioncalcium channel activity
A0005509molecular_functioncalcium ion binding
A0005513biological_processdetection of calcium ion
A0005515molecular_functionprotein binding
A0005516molecular_functioncalmodulin binding
A0005790cellular_componentsmooth endoplasmic reticulum
A0006811biological_processmonoatomic ion transport
A0006816biological_processcalcium ion transport
A0006874biological_processintracellular calcium ion homeostasis
A0010460biological_processpositive regulation of heart rate
A0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
A0010882biological_processregulation of cardiac muscle contraction by calcium ion signaling
A0014808biological_processrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum
A0014850biological_processresponse to muscle activity
A0015278molecular_functionintracellularly gated calcium channel activity
A0016020cellular_componentmembrane
A0016529cellular_componentsarcoplasmic reticulum
A0019722biological_processcalcium-mediated signaling
A0019899molecular_functionenzyme binding
A0019901molecular_functionprotein kinase binding
A0030017cellular_componentsarcomere
A0030018cellular_componentZ disc
A0031000biological_processresponse to caffeine
A0032991cellular_componentprotein-containing complex
A0033017cellular_componentsarcoplasmic reticulum membrane
A0034236molecular_functionprotein kinase A catalytic subunit binding
A0034237molecular_functionprotein kinase A regulatory subunit binding
A0034704cellular_componentcalcium channel complex
A0035994biological_processresponse to muscle stretch
A0042802molecular_functionidentical protein binding
A0043924molecular_functionsuramin binding
A0048763molecular_functioncalcium-induced calcium release activity
A0051209biological_processrelease of sequestered calcium ion into cytosol
A0051284biological_processpositive regulation of sequestering of calcium ion
A0051649biological_processestablishment of localization in cell
A0051775biological_processresponse to redox state
A0055085biological_processtransmembrane transport
A0055117biological_processregulation of cardiac muscle contraction
A0060048biological_processcardiac muscle contraction
A0060402biological_processcalcium ion transport into cytosol
A0070588biological_processcalcium ion transmembrane transport
A0071313biological_processcellular response to caffeine
A0071872biological_processcellular response to epinephrine stimulus
A0072599biological_processestablishment of protein localization to endoplasmic reticulum
A0086005biological_processventricular cardiac muscle cell action potential
A0086029biological_processPurkinje myocyte to ventricular cardiac muscle cell signaling
A0097050biological_processtype B pancreatic cell apoptotic process
A0097159molecular_functionorganic cyclic compound binding
A0097553biological_processcalcium ion transmembrane import into cytosol
A0098735biological_processpositive regulation of the force of heart contraction
A0098904biological_processregulation of AV node cell action potential
A0098907biological_processregulation of SA node cell action potential
A0098910biological_processregulation of atrial cardiac muscle cell action potential
A0098911biological_processregulation of ventricular cardiac muscle cell action potential
B0001666biological_processresponse to hypoxia
B0002027biological_processregulation of heart rate
B0003143biological_processembryonic heart tube morphogenesis
B0003220biological_processleft ventricular cardiac muscle tissue morphogenesis
B0003300biological_processcardiac muscle hypertrophy
B0005216molecular_functionmonoatomic ion channel activity
B0005219molecular_functionryanodine-sensitive calcium-release channel activity
B0005262molecular_functioncalcium channel activity
B0005509molecular_functioncalcium ion binding
B0005513biological_processdetection of calcium ion
B0005515molecular_functionprotein binding
B0005516molecular_functioncalmodulin binding
B0005790cellular_componentsmooth endoplasmic reticulum
B0006811biological_processmonoatomic ion transport
B0006816biological_processcalcium ion transport
B0006874biological_processintracellular calcium ion homeostasis
B0010460biological_processpositive regulation of heart rate
B0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
B0010882biological_processregulation of cardiac muscle contraction by calcium ion signaling
B0014808biological_processrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum
B0014850biological_processresponse to muscle activity
B0015278molecular_functionintracellularly gated calcium channel activity
B0016020cellular_componentmembrane
B0016529cellular_componentsarcoplasmic reticulum
B0019722biological_processcalcium-mediated signaling
B0019899molecular_functionenzyme binding
B0019901molecular_functionprotein kinase binding
B0030017cellular_componentsarcomere
B0030018cellular_componentZ disc
B0031000biological_processresponse to caffeine
B0032991cellular_componentprotein-containing complex
B0033017cellular_componentsarcoplasmic reticulum membrane
B0034236molecular_functionprotein kinase A catalytic subunit binding
B0034237molecular_functionprotein kinase A regulatory subunit binding
B0034704cellular_componentcalcium channel complex
B0035994biological_processresponse to muscle stretch
B0042802molecular_functionidentical protein binding
B0043924molecular_functionsuramin binding
B0048763molecular_functioncalcium-induced calcium release activity
B0051209biological_processrelease of sequestered calcium ion into cytosol
B0051284biological_processpositive regulation of sequestering of calcium ion
B0051649biological_processestablishment of localization in cell
B0051775biological_processresponse to redox state
B0055085biological_processtransmembrane transport
B0055117biological_processregulation of cardiac muscle contraction
B0060048biological_processcardiac muscle contraction
B0060402biological_processcalcium ion transport into cytosol
B0070588biological_processcalcium ion transmembrane transport
B0071313biological_processcellular response to caffeine
B0071872biological_processcellular response to epinephrine stimulus
B0072599biological_processestablishment of protein localization to endoplasmic reticulum
B0086005biological_processventricular cardiac muscle cell action potential
B0086029biological_processPurkinje myocyte to ventricular cardiac muscle cell signaling
B0097050biological_processtype B pancreatic cell apoptotic process
B0097159molecular_functionorganic cyclic compound binding
B0097553biological_processcalcium ion transmembrane import into cytosol
B0098735biological_processpositive regulation of the force of heart contraction
B0098904biological_processregulation of AV node cell action potential
B0098907biological_processregulation of SA node cell action potential
B0098910biological_processregulation of atrial cardiac muscle cell action potential
B0098911biological_processregulation of ventricular cardiac muscle cell action potential
C0001666biological_processresponse to hypoxia
C0002027biological_processregulation of heart rate
C0003143biological_processembryonic heart tube morphogenesis
C0003220biological_processleft ventricular cardiac muscle tissue morphogenesis
C0003300biological_processcardiac muscle hypertrophy
C0005216molecular_functionmonoatomic ion channel activity
C0005219molecular_functionryanodine-sensitive calcium-release channel activity
C0005262molecular_functioncalcium channel activity
C0005509molecular_functioncalcium ion binding
C0005513biological_processdetection of calcium ion
C0005515molecular_functionprotein binding
C0005516molecular_functioncalmodulin binding
C0005790cellular_componentsmooth endoplasmic reticulum
C0006811biological_processmonoatomic ion transport
C0006816biological_processcalcium ion transport
C0006874biological_processintracellular calcium ion homeostasis
C0010460biological_processpositive regulation of heart rate
C0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
C0010882biological_processregulation of cardiac muscle contraction by calcium ion signaling
C0014808biological_processrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum
C0014850biological_processresponse to muscle activity
C0015278molecular_functionintracellularly gated calcium channel activity
C0016020cellular_componentmembrane
C0016529cellular_componentsarcoplasmic reticulum
C0019722biological_processcalcium-mediated signaling
C0019899molecular_functionenzyme binding
C0019901molecular_functionprotein kinase binding
C0030017cellular_componentsarcomere
C0030018cellular_componentZ disc
C0031000biological_processresponse to caffeine
C0032991cellular_componentprotein-containing complex
C0033017cellular_componentsarcoplasmic reticulum membrane
C0034236molecular_functionprotein kinase A catalytic subunit binding
C0034237molecular_functionprotein kinase A regulatory subunit binding
C0034704cellular_componentcalcium channel complex
C0035994biological_processresponse to muscle stretch
C0042802molecular_functionidentical protein binding
C0043924molecular_functionsuramin binding
C0048763molecular_functioncalcium-induced calcium release activity
C0051209biological_processrelease of sequestered calcium ion into cytosol
C0051284biological_processpositive regulation of sequestering of calcium ion
C0051649biological_processestablishment of localization in cell
C0051775biological_processresponse to redox state
C0055085biological_processtransmembrane transport
C0055117biological_processregulation of cardiac muscle contraction
C0060048biological_processcardiac muscle contraction
C0060402biological_processcalcium ion transport into cytosol
C0070588biological_processcalcium ion transmembrane transport
C0071313biological_processcellular response to caffeine
C0071872biological_processcellular response to epinephrine stimulus
C0072599biological_processestablishment of protein localization to endoplasmic reticulum
C0086005biological_processventricular cardiac muscle cell action potential
C0086029biological_processPurkinje myocyte to ventricular cardiac muscle cell signaling
C0097050biological_processtype B pancreatic cell apoptotic process
C0097159molecular_functionorganic cyclic compound binding
C0097553biological_processcalcium ion transmembrane import into cytosol
C0098735biological_processpositive regulation of the force of heart contraction
C0098904biological_processregulation of AV node cell action potential
C0098907biological_processregulation of SA node cell action potential
C0098910biological_processregulation of atrial cardiac muscle cell action potential
C0098911biological_processregulation of ventricular cardiac muscle cell action potential
D0001666biological_processresponse to hypoxia
D0002027biological_processregulation of heart rate
D0003143biological_processembryonic heart tube morphogenesis
D0003220biological_processleft ventricular cardiac muscle tissue morphogenesis
D0003300biological_processcardiac muscle hypertrophy
D0005216molecular_functionmonoatomic ion channel activity
D0005219molecular_functionryanodine-sensitive calcium-release channel activity
D0005262molecular_functioncalcium channel activity
D0005509molecular_functioncalcium ion binding
D0005513biological_processdetection of calcium ion
D0005515molecular_functionprotein binding
D0005516molecular_functioncalmodulin binding
D0005790cellular_componentsmooth endoplasmic reticulum
D0006811biological_processmonoatomic ion transport
D0006816biological_processcalcium ion transport
D0006874biological_processintracellular calcium ion homeostasis
D0010460biological_processpositive regulation of heart rate
D0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
D0010882biological_processregulation of cardiac muscle contraction by calcium ion signaling
D0014808biological_processrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum
D0014850biological_processresponse to muscle activity
D0015278molecular_functionintracellularly gated calcium channel activity
D0016020cellular_componentmembrane
D0016529cellular_componentsarcoplasmic reticulum
D0019722biological_processcalcium-mediated signaling
D0019899molecular_functionenzyme binding
D0019901molecular_functionprotein kinase binding
D0030017cellular_componentsarcomere
D0030018cellular_componentZ disc
D0031000biological_processresponse to caffeine
D0032991cellular_componentprotein-containing complex
D0033017cellular_componentsarcoplasmic reticulum membrane
D0034236molecular_functionprotein kinase A catalytic subunit binding
D0034237molecular_functionprotein kinase A regulatory subunit binding
D0034704cellular_componentcalcium channel complex
D0035994biological_processresponse to muscle stretch
D0042802molecular_functionidentical protein binding
D0043924molecular_functionsuramin binding
D0048763molecular_functioncalcium-induced calcium release activity
D0051209biological_processrelease of sequestered calcium ion into cytosol
D0051284biological_processpositive regulation of sequestering of calcium ion
D0051649biological_processestablishment of localization in cell
D0051775biological_processresponse to redox state
D0055085biological_processtransmembrane transport
D0055117biological_processregulation of cardiac muscle contraction
D0060048biological_processcardiac muscle contraction
D0060402biological_processcalcium ion transport into cytosol
D0070588biological_processcalcium ion transmembrane transport
D0071313biological_processcellular response to caffeine
D0071872biological_processcellular response to epinephrine stimulus
D0072599biological_processestablishment of protein localization to endoplasmic reticulum
D0086005biological_processventricular cardiac muscle cell action potential
D0086029biological_processPurkinje myocyte to ventricular cardiac muscle cell signaling
D0097050biological_processtype B pancreatic cell apoptotic process
D0097159molecular_functionorganic cyclic compound binding
D0097553biological_processcalcium ion transmembrane import into cytosol
D0098735biological_processpositive regulation of the force of heart contraction
D0098904biological_processregulation of AV node cell action potential
D0098907biological_processregulation of SA node cell action potential
D0098910biological_processregulation of atrial cardiac muscle cell action potential
D0098911biological_processregulation of ventricular cardiac muscle cell action potential
E0002027biological_processregulation of heart rate
E0003755molecular_functionpeptidyl-prolyl cis-trans isomerase activity
E0005102molecular_functionsignaling receptor binding
E0005219molecular_functionryanodine-sensitive calcium-release channel activity
E0005515molecular_functionprotein binding
E0005528molecular_functionFK506 binding
E0005737cellular_componentcytoplasm
E0006458biological_process'de novo' protein folding
E0006939biological_processsmooth muscle contraction
E0007204biological_processpositive regulation of cytosolic calcium ion concentration
E0009749biological_processresponse to glucose
E0010459biological_processnegative regulation of heart rate
E0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
E0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
E0016020cellular_componentmembrane
E0016247molecular_functionchannel regulator activity
E0016529cellular_componentsarcoplasmic reticulum
E0019227biological_processneuronal action potential propagation
E0019722biological_processcalcium-mediated signaling
E0019855molecular_functioncalcium channel inhibitor activity
E0022417biological_processprotein maturation by protein folding
E0030018cellular_componentZ disc
E0030073biological_processinsulin secretion
E0030551molecular_functioncyclic nucleotide binding
E0033017cellular_componentsarcoplasmic reticulum membrane
E0033197biological_processresponse to vitamin E
E0034704cellular_componentcalcium channel complex
E0035773biological_processinsulin secretion involved in cellular response to glucose stimulus
E0042026biological_processprotein refolding
E0042098biological_processT cell proliferation
E0042542biological_processresponse to hydrogen peroxide
E0044325molecular_functiontransmembrane transporter binding
E0048680biological_processpositive regulation of axon regeneration
E0050849biological_processnegative regulation of calcium-mediated signaling
E0051209biological_processrelease of sequestered calcium ion into cytosol
E0051280biological_processnegative regulation of release of sequestered calcium ion into cytosol
E0051284biological_processpositive regulation of sequestering of calcium ion
E0051775biological_processresponse to redox state
E0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
E0061179biological_processnegative regulation of insulin secretion involved in cellular response to glucose stimulus
F0002027biological_processregulation of heart rate
F0003755molecular_functionpeptidyl-prolyl cis-trans isomerase activity
F0005102molecular_functionsignaling receptor binding
F0005219molecular_functionryanodine-sensitive calcium-release channel activity
F0005515molecular_functionprotein binding
F0005528molecular_functionFK506 binding
F0005737cellular_componentcytoplasm
F0006458biological_process'de novo' protein folding
F0006939biological_processsmooth muscle contraction
F0007204biological_processpositive regulation of cytosolic calcium ion concentration
F0009749biological_processresponse to glucose
F0010459biological_processnegative regulation of heart rate
F0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
F0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
F0016020cellular_componentmembrane
F0016247molecular_functionchannel regulator activity
F0016529cellular_componentsarcoplasmic reticulum
F0019227biological_processneuronal action potential propagation
F0019722biological_processcalcium-mediated signaling
F0019855molecular_functioncalcium channel inhibitor activity
F0022417biological_processprotein maturation by protein folding
F0030018cellular_componentZ disc
F0030073biological_processinsulin secretion
F0030551molecular_functioncyclic nucleotide binding
F0033017cellular_componentsarcoplasmic reticulum membrane
F0033197biological_processresponse to vitamin E
F0034704cellular_componentcalcium channel complex
F0035773biological_processinsulin secretion involved in cellular response to glucose stimulus
F0042026biological_processprotein refolding
F0042098biological_processT cell proliferation
F0042542biological_processresponse to hydrogen peroxide
F0044325molecular_functiontransmembrane transporter binding
F0048680biological_processpositive regulation of axon regeneration
F0050849biological_processnegative regulation of calcium-mediated signaling
F0051209biological_processrelease of sequestered calcium ion into cytosol
F0051280biological_processnegative regulation of release of sequestered calcium ion into cytosol
F0051284biological_processpositive regulation of sequestering of calcium ion
F0051775biological_processresponse to redox state
F0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
F0061179biological_processnegative regulation of insulin secretion involved in cellular response to glucose stimulus
G0002027biological_processregulation of heart rate
G0003755molecular_functionpeptidyl-prolyl cis-trans isomerase activity
G0005102molecular_functionsignaling receptor binding
G0005219molecular_functionryanodine-sensitive calcium-release channel activity
G0005515molecular_functionprotein binding
G0005528molecular_functionFK506 binding
G0005737cellular_componentcytoplasm
G0006458biological_process'de novo' protein folding
G0006939biological_processsmooth muscle contraction
G0007204biological_processpositive regulation of cytosolic calcium ion concentration
G0009749biological_processresponse to glucose
G0010459biological_processnegative regulation of heart rate
G0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
G0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
G0016020cellular_componentmembrane
G0016247molecular_functionchannel regulator activity
G0016529cellular_componentsarcoplasmic reticulum
G0019227biological_processneuronal action potential propagation
G0019722biological_processcalcium-mediated signaling
G0019855molecular_functioncalcium channel inhibitor activity
G0022417biological_processprotein maturation by protein folding
G0030018cellular_componentZ disc
G0030073biological_processinsulin secretion
G0030551molecular_functioncyclic nucleotide binding
G0033017cellular_componentsarcoplasmic reticulum membrane
G0033197biological_processresponse to vitamin E
G0034704cellular_componentcalcium channel complex
G0035773biological_processinsulin secretion involved in cellular response to glucose stimulus
G0042026biological_processprotein refolding
G0042098biological_processT cell proliferation
G0042542biological_processresponse to hydrogen peroxide
G0044325molecular_functiontransmembrane transporter binding
G0048680biological_processpositive regulation of axon regeneration
G0050849biological_processnegative regulation of calcium-mediated signaling
G0051209biological_processrelease of sequestered calcium ion into cytosol
G0051280biological_processnegative regulation of release of sequestered calcium ion into cytosol
G0051284biological_processpositive regulation of sequestering of calcium ion
G0051775biological_processresponse to redox state
G0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
G0061179biological_processnegative regulation of insulin secretion involved in cellular response to glucose stimulus
H0002027biological_processregulation of heart rate
H0003755molecular_functionpeptidyl-prolyl cis-trans isomerase activity
H0005102molecular_functionsignaling receptor binding
H0005219molecular_functionryanodine-sensitive calcium-release channel activity
H0005515molecular_functionprotein binding
H0005528molecular_functionFK506 binding
H0005737cellular_componentcytoplasm
H0006458biological_process'de novo' protein folding
H0006939biological_processsmooth muscle contraction
H0007204biological_processpositive regulation of cytosolic calcium ion concentration
H0009749biological_processresponse to glucose
H0010459biological_processnegative regulation of heart rate
H0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
H0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
H0016020cellular_componentmembrane
H0016247molecular_functionchannel regulator activity
H0016529cellular_componentsarcoplasmic reticulum
H0019227biological_processneuronal action potential propagation
H0019722biological_processcalcium-mediated signaling
H0019855molecular_functioncalcium channel inhibitor activity
H0022417biological_processprotein maturation by protein folding
H0030018cellular_componentZ disc
H0030073biological_processinsulin secretion
H0030551molecular_functioncyclic nucleotide binding
H0033017cellular_componentsarcoplasmic reticulum membrane
H0033197biological_processresponse to vitamin E
H0034704cellular_componentcalcium channel complex
H0035773biological_processinsulin secretion involved in cellular response to glucose stimulus
H0042026biological_processprotein refolding
H0042098biological_processT cell proliferation
H0042542biological_processresponse to hydrogen peroxide
H0044325molecular_functiontransmembrane transporter binding
H0048680biological_processpositive regulation of axon regeneration
H0050849biological_processnegative regulation of calcium-mediated signaling
H0051209biological_processrelease of sequestered calcium ion into cytosol
H0051280biological_processnegative regulation of release of sequestered calcium ion into cytosol
H0051284biological_processpositive regulation of sequestering of calcium ion
H0051775biological_processresponse to redox state
H0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
H0061179biological_processnegative regulation of insulin secretion involved in cellular response to glucose stimulus
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue ZN A 6000
ChainResidue
ACYS4887
ACYS4890
AHIS4907
AHIS4912

site_idAC2
Number of Residues4
Detailsbinding site for residue ZN B 6000
ChainResidue
BCYS4887
BCYS4890
BHIS4907
BHIS4912

site_idAC3
Number of Residues4
Detailsbinding site for residue ZN C 6000
ChainResidue
CCYS4890
CHIS4907
CHIS4912
CCYS4887

site_idAC4
Number of Residues4
Detailsbinding site for residue ZN D 6000
ChainResidue
DCYS4887
DCYS4890
DHIS4907
DHIS4912

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues17304
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
AMET1-ARG4231
AGLY4870-ASN4966
BMET1-ARG4231
BGLY4870-ASN4966
CMET1-ARG4231
CGLY4870-ASN4966
DMET1-ARG4231
DGLY4870-ASN4966

site_idSWS_FT_FI2
Number of Residues560
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
AMET4232-LEU4252
BMET4502-THR4522
BTHR4579-PHE4599
BVAL4729-PHE4749
BLEU4768-PHE4788
BPHE4849-PHE4869
CMET4232-LEU4252
CMET4278-ALA4298
CMET4502-THR4522
CTHR4579-PHE4599
CVAL4729-PHE4749
AMET4278-ALA4298
CLEU4768-PHE4788
CPHE4849-PHE4869
DMET4232-LEU4252
DMET4278-ALA4298
DMET4502-THR4522
DTHR4579-PHE4599
DVAL4729-PHE4749
DLEU4768-PHE4788
DPHE4849-PHE4869
AMET4502-THR4522
ATHR4579-PHE4599
AVAL4729-PHE4749
ALEU4768-PHE4788
APHE4849-PHE4869
BMET4232-LEU4252
BMET4278-ALA4298

site_idSWS_FT_FI3
Number of Residues36
DetailsINTRAMEM: Pore-forming => ECO:0000305
ChainResidueDetails
AGLY4819-ASP4828
BGLY4819-ASP4828
CGLY4819-ASP4828
DGLY4819-ASP4828

site_idSWS_FT_FI4
Number of Residues20
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079
ChainResidueDetails
ASER1341
BSER2946
CSER1341
CSER2368
CSER2796
CSER2810
CSER2946
DSER1341
DSER2368
DSER2796
DSER2810
ASER2368
DSER2946
ASER2796
ASER2810
ASER2946
BSER1341
BSER2368
BSER2796
BSER2810

site_idSWS_FT_FI5
Number of Residues8
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:B0LPN4
ChainResidueDetails
ASER1870
ASER2696
BSER1870
BSER2696
CSER1870
CSER2696
DSER1870
DSER2696

site_idSWS_FT_FI6
Number of Residues4
DetailsMOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:17693412
ChainResidueDetails
ASER2030
BSER2030
CSER2030
DSER2030

site_idSWS_FT_FI7
Number of Residues4
DetailsMOD_RES: Phosphoserine; by CaMK2D and PKA => ECO:0000269|PubMed:20431056, ECO:0000269|PubMed:21098440, ECO:0007744|PubMed:21183079
ChainResidueDetails
ASER2807
BSER2807
CSER2807
DSER2807

site_idSWS_FT_FI8
Number of Residues4
DetailsMOD_RES: Phosphoserine; by CaMK2D => ECO:0000269|PubMed:21098440, ECO:0007744|PubMed:21183079
ChainResidueDetails
ASER2813
BSER2813
CSER2813
DSER2813

226707

PDB entries from 2024-10-30

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