6WND
Structure of the Rieske non-heme iron oxygenase GxtA with dideoxysaxitoxin bound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051536 | molecular_function | iron-sulfur cluster binding |
| C | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue FES A 501 |
| Chain | Residue |
| A | CYS55 |
| A | HIS57 |
| A | ARG58 |
| A | CYS74 |
| A | HIS77 |
| A | TRP79 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | GLU111 |
| A | PRO47 |
| A | ILE48 |
| A | CYS109 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | HIS139 |
| A | LYS140 |
| A | LYS263 |
| A | HOH609 |
| C | GOL504 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | LYS144 |
| A | ASP274 |
| A | GLU278 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 505 |
| Chain | Residue |
| A | GLU248 |
| A | THR330 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue U5A A 506 |
| Chain | Residue |
| A | SER159 |
| A | PHE165 |
| A | ILE172 |
| A | ASN216 |
| A | GLN226 |
| A | CYS228 |
| A | ASP239 |
| A | TYR255 |
| A | ASP272 |
| A | TYR273 |
| A | VAL276 |
| A | HOH671 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue FE A 507 |
| Chain | Residue |
| A | HIS164 |
| A | HIS169 |
| A | ASP280 |
| A | HOH601 |
| A | HOH671 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 508 |
| Chain | Residue |
| A | SER41 |
| A | HIS42 |
| A | ASN69 |
| A | ASN70 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 509 |
| Chain | Residue |
| A | GLN149 |
| A | HIS285 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue FES B 501 |
| Chain | Residue |
| B | CYS55 |
| B | HIS57 |
| B | ARG58 |
| B | CYS74 |
| B | HIS77 |
| B | TRP79 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 502 |
| Chain | Residue |
| B | HIS139 |
| B | LYS140 |
| B | LYS263 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 503 |
| Chain | Residue |
| B | THR3 |
| B | GLU248 |
| B | THR330 |
| B | VAL333 |
| site_id | AD4 |
| Number of Residues | 11 |
| Details | binding site for residue U5A B 504 |
| Chain | Residue |
| B | SER159 |
| B | PHE165 |
| B | ASN216 |
| B | GLN226 |
| B | CYS228 |
| B | ASP239 |
| B | TYR255 |
| B | ASP272 |
| B | TYR273 |
| B | HOH610 |
| B | HOH662 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue FE B 505 |
| Chain | Residue |
| B | HIS164 |
| B | HIS169 |
| B | ASP280 |
| B | HOH610 |
| B | HOH672 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 506 |
| Chain | Residue |
| B | ARG22 |
| B | PRO23 |
| B | ARG40 |
| B | ASN45 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 507 |
| Chain | Residue |
| B | THR143 |
| B | LYS144 |
| B | TYR146 |
| C | GLU19 |
| C | ASP20 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue FES C 501 |
| Chain | Residue |
| C | CYS55 |
| C | HIS57 |
| C | ARG58 |
| C | CYS74 |
| C | HIS77 |
| C | TRP79 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 502 |
| Chain | Residue |
| C | HIS139 |
| C | LYS140 |
| C | LYS263 |
| C | HOH699 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 503 |
| Chain | Residue |
| C | LEU305 |
| C | GLN307 |
| C | CYS334 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 504 |
| Chain | Residue |
| A | GOL503 |
| A | HOH609 |
| C | VAL88 |
| C | GLN89 |
| C | PRO94 |
| site_id | AE3 |
| Number of Residues | 11 |
| Details | binding site for residue U5A C 505 |
| Chain | Residue |
| C | SER159 |
| C | PHE165 |
| C | ASN216 |
| C | GLN226 |
| C | CYS228 |
| C | ASP239 |
| C | TYR255 |
| C | TYR273 |
| C | VAL276 |
| C | HOH603 |
| C | HOH700 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue FE C 506 |
| Chain | Residue |
| C | HIS164 |
| C | HIS169 |
| C | ASP280 |
| C | HOH694 |
| C | HOH700 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 507 |
| Chain | Residue |
| C | PRO47 |
| C | ILE48 |
| C | CYS109 |
| C | GLN110 |
| C | GLU111 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 508 |
| Chain | Residue |
| C | GLN149 |
| C | HIS285 |
| C | THR290 |
| C | HOH657 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 509 |
| Chain | Residue |
| C | GLU248 |
| C | ARG291 |
| C | THR330 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue CL C 510 |
| Chain | Residue |
| C | SER41 |
| C | HIS42 |
| C | ASN69 |
| C | ASN70 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 511 |
| Chain | Residue |
| C | GLN149 |
| C | HIS285 |
Functional Information from PROSITE/UniProt
| site_id | PS00570 |
| Number of Residues | 23 |
| Details | RING_HYDROXYL_ALPHA Bacterial ring hydroxylating dioxygenases alpha-subunit signature. CpHRGvplsmge.VAnntlvCpYH |
| Chain | Residue | Details |
| A | CYS55-HIS77 |
