Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
A | 0004831 | molecular_function | tyrosine-tRNA ligase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
A | 0006437 | biological_process | tyrosyl-tRNA aminoacylation |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
B | 0004831 | molecular_function | tyrosine-tRNA ligase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
B | 0006437 | biological_process | tyrosyl-tRNA aminoacylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | binding site for residue TYS A 401 |
Chain | Residue |
A | TYR37 |
A | GLN179 |
A | GLY182 |
A | LEU186 |
A | GLN201 |
A | HOH524 |
A | HOH550 |
A | HOH568 |
A | HOH581 |
A | GLY39 |
A | PHE40 |
A | ASP41 |
A | VAL71 |
A | ASP81 |
A | ASN126 |
A | PHE129 |
A | TYR175 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue PG4 A 402 |
Chain | Residue |
A | GLU88 |
A | GLU164 |
A | HOH528 |
A | HOH557 |
B | LYS144 |
B | SER147 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue PG4 A 403 |
Chain | Residue |
A | ASP45 |
A | TRP100 |
A | TRP245 |
A | LYS250 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue PG4 A 404 |
Chain | Residue |
A | HIS145 |
A | PHE146 |
A | SER147 |
A | GLN150 |
A | ARG214 |
A | HOH502 |
site_id | AC5 |
Number of Residues | 3 |
Details | binding site for residue NA A 405 |
Chain | Residue |
A | SO4408 |
A | HOH582 |
A | HOH593 |
site_id | AC6 |
Number of Residues | 6 |
Details | binding site for residue NA A 406 |
Chain | Residue |
A | ILE79 |
A | ARG89 |
A | LEU91 |
A | GLU172 |
A | HOH522 |
A | HOH575 |
site_id | AC7 |
Number of Residues | 3 |
Details | binding site for residue SO4 A 407 |
Chain | Residue |
A | LYS85 |
A | ALA86 |
A | ALA87 |
site_id | AC8 |
Number of Residues | 5 |
Details | binding site for residue SO4 A 408 |
Chain | Residue |
A | LYS154 |
A | TRP202 |
A | GLY203 |
A | THR206 |
A | NA405 |
site_id | AC9 |
Number of Residues | 3 |
Details | binding site for residue SO4 A 409 |
Chain | Residue |
A | THR43 |
A | HIS48 |
A | ARG89 |
site_id | AD1 |
Number of Residues | 16 |
Details | binding site for residue TYS B 401 |
Chain | Residue |
B | TYR37 |
B | GLY39 |
B | PHE40 |
B | ASP41 |
B | VAL71 |
B | ASP81 |
B | ASN126 |
B | TYR175 |
B | GLN179 |
B | GLY182 |
B | LEU186 |
B | GLN201 |
B | HOH528 |
B | HOH544 |
B | HOH587 |
B | HOH601 |
site_id | AD2 |
Number of Residues | 3 |
Details | binding site for residue PG4 B 402 |
Chain | Residue |
A | LYS295 |
B | TRP245 |
B | LYS250 |
site_id | AD3 |
Number of Residues | 11 |
Details | binding site for residue PG4 B 403 |
Chain | Residue |
B | HIS145 |
B | PHE146 |
B | SER147 |
B | GLN150 |
B | SER207 |
B | ASP210 |
B | ARG213 |
B | ARG214 |
B | HOH501 |
B | HOH524 |
B | HOH579 |
site_id | AD4 |
Number of Residues | 6 |
Details | binding site for residue NA B 404 |
Chain | Residue |
B | ILE79 |
B | ARG89 |
B | LEU91 |
B | GLU172 |
B | HOH535 |
B | HOH541 |
site_id | AD5 |
Number of Residues | 5 |
Details | binding site for residue NA B 405 |
Chain | Residue |
B | ASN5 |
B | ALA26 |
B | LEU29 |
B | ALA30 |
B | HOH642 |
site_id | AD6 |
Number of Residues | 4 |
Details | binding site for residue SO4 B 406 |
Chain | Residue |
B | LYS85 |
B | ALA86 |
B | ALA87 |
B | HOH507 |
site_id | AD7 |
Number of Residues | 5 |
Details | binding site for residue SO4 B 407 |
Chain | Residue |
B | TRP202 |
B | THR206 |
B | HOH610 |
B | HOH628 |
B | LYS154 |
site_id | AD8 |
Number of Residues | 3 |
Details | binding site for residue SO4 B 408 |
Chain | Residue |
B | HIS48 |
B | ARG89 |
B | HOH504 |
site_id | AD9 |
Number of Residues | 4 |
Details | binding site for residue SO4 B 409 |
Chain | Residue |
B | ARG105 |
B | LYS230 |
B | GLY233 |
B | HOH577 |
Functional Information from PROSITE/UniProt
site_id | PS00178 |
Number of Residues | 11 |
Details | AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. Pt.ADsLHLGHL |
Chain | Residue | Details |
A | PRO42-LEU52 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | TYR37 | |
B | TYR37 | |
Chain | Residue | Details |
A | TYR175 | |
A | GLN179 | |
B | TYR175 | |
B | GLN179 | |
Chain | Residue | Details |
A | LYS238 | |
B | LYS238 | |
site_id | SWS_FT_FI4 |
Number of Residues | 4 |
Details | SITE: Cross-linked with tRNA by periodate oxidation |
Chain | Residue | Details |
A | ALA231 | |
A | LYS238 | |
B | ALA231 | |
B | LYS238 | |
site_id | SWS_FT_FI5 |
Number of Residues | 2 |
Details | SITE: Cross-linked with tRNA by periodate oxidation; predominant |
Chain | Residue | Details |
A | LYS235 | |
B | LYS235 | |
Chain | Residue | Details |
A | LYS144 | |
B | LYS144 | |