Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6WHL

The crystal structure of a beta-lactamase from Legionella pneumophila str. Paris

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008658	molecular_function	penicillin binding
A	0008800	molecular_function	beta-lactamase activity
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0046677	biological_process	response to antibiotic
B	0008658	molecular_function	penicillin binding
B	0008800	molecular_function	beta-lactamase activity
B	0016787	molecular_function	hydrolase activity
B	0017001	biological_process	antibiotic catabolic process
B	0046677	biological_process	response to antibiotic
C	0008658	molecular_function	penicillin binding
C	0008800	molecular_function	beta-lactamase activity
C	0016787	molecular_function	hydrolase activity
C	0017001	biological_process	antibiotic catabolic process
C	0046677	biological_process	response to antibiotic
D	0008658	molecular_function	penicillin binding
D	0008800	molecular_function	beta-lactamase activity
D	0016787	molecular_function	hydrolase activity
D	0017001	biological_process	antibiotic catabolic process
D	0046677	biological_process	response to antibiotic
E	0008658	molecular_function	penicillin binding
E	0008800	molecular_function	beta-lactamase activity
E	0016787	molecular_function	hydrolase activity
E	0017001	biological_process	antibiotic catabolic process
E	0046677	biological_process	response to antibiotic
F	0008658	molecular_function	penicillin binding
F	0008800	molecular_function	beta-lactamase activity
F	0016787	molecular_function	hydrolase activity
F	0017001	biological_process	antibiotic catabolic process
F	0046677	biological_process	response to antibiotic
G	0008658	molecular_function	penicillin binding
G	0008800	molecular_function	beta-lactamase activity
G	0016787	molecular_function	hydrolase activity
G	0017001	biological_process	antibiotic catabolic process
G	0046677	biological_process	response to antibiotic
H	0008658	molecular_function	penicillin binding
H	0008800	molecular_function	beta-lactamase activity
H	0016787	molecular_function	hydrolase activity
H	0017001	biological_process	antibiotic catabolic process
H	0046677	biological_process	response to antibiotic
I	0008658	molecular_function	penicillin binding
I	0008800	molecular_function	beta-lactamase activity
I	0016787	molecular_function	hydrolase activity
I	0017001	biological_process	antibiotic catabolic process
I	0046677	biological_process	response to antibiotic
J	0008658	molecular_function	penicillin binding
J	0008800	molecular_function	beta-lactamase activity
J	0016787	molecular_function	hydrolase activity
J	0017001	biological_process	antibiotic catabolic process
J	0046677	biological_process	response to antibiotic
K	0008658	molecular_function	penicillin binding
K	0008800	molecular_function	beta-lactamase activity
K	0016787	molecular_function	hydrolase activity
K	0017001	biological_process	antibiotic catabolic process
K	0046677	biological_process	response to antibiotic
L	0008658	molecular_function	penicillin binding
L	0008800	molecular_function	beta-lactamase activity
L	0016787	molecular_function	hydrolase activity
L	0017001	biological_process	antibiotic catabolic process
L	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue GOL A 301

Chain	Residue
A	LYS250
A	ASN251

site_id	AC2
Number of Residues	3
Details	binding site for residue GOL B 301

Chain	Residue
B	PHE247
B	LYS250
B	ASN251

site_id	AC3
Number of Residues	2
Details	binding site for residue GOL C 301

Chain	Residue
C	PHE258
D	LYS250

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL C 302

Chain	Residue
D	LEU254
D	PHE258
C	LYS250
D	GLN185

site_id	AC5
Number of Residues	2
Details	binding site for residue GOL E 301

Chain	Residue
E	PHE247
E	LYS250

site_id	AC6
Number of Residues	4
Details	binding site for residue GOL F 301

Chain	Residue
E	LEU254
F	PHE247
F	LYS250
F	ASN251

site_id	AC7
Number of Residues	3
Details	binding site for residue GOL G 301

Chain	Residue
G	PHE247
G	LYS250
G	ASN251

site_id	AC8
Number of Residues	3
Details	binding site for residue GOL H 301

Chain	Residue
H	PHE247
H	LYS250
H	ASN251

site_id	AC9
Number of Residues	4
Details	binding site for residue GOL I 301

Chain	Residue
I	PHE247
I	LYS250
I	ASN251
J	LEU254

site_id	AD1
Number of Residues	3
Details	binding site for residue GOL J 301

Chain	Residue
J	PHE247
J	LYS250
J	ASN251

site_id	AD2
Number of Residues	3
Details	binding site for residue GOL K 301

Chain	Residue
K	GLN185
L	PHE247
L	LYS250

site_id	AD3
Number of Residues	1
Details	binding site for residue GOL L 301

Chain	Residue
L	LEU254

Functional Information from PROSITE/UniProt

site_id	PS00337
Number of Residues	11
Details	BETA_LACTAMASE_D Beta-lactamase class-D active site. PaSTFKIAlSL

Chain	Residue	Details
A	PRO47-LEU57

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)