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6WG8

Fab portion of dupilumab with Crystal Kappa design

Functional Information from PDB Data
site_idAC1
Number of Residues11
Detailsbinding site for residue GOL A 301
ChainResidue
APHE178
BSER182
BTHR183
APRO179
AVAL181
ASER189
ALEU190
ASER191
AHOH403
BSER167
BSER181

site_idAC2
Number of Residues9
Detailsbinding site for residue GOL A 302
ChainResidue
ATYR60
ALYS65
AGLY66
AARG67
APHE68
ATHR69
AHOH417
BALA189
BLYS193

site_idAC3
Number of Residues7
Detailsbinding site for residue GOL A 303
ChainResidue
AGLY42
ALYS43
AGLY44
AHOH436
BPHE90
BTYR92
BGLN105

site_idAC4
Number of Residues11
Detailsbinding site for residue GOL B 301
ChainResidue
AASP31
ATYR32
AHOH453
BALA149
BLYS150
BTHR202
BGLN203
BGLY204
BHOH406
BHOH415
BHOH427

site_idAC5
Number of Residues7
Detailsbinding site for residue GOL B 302
ChainResidue
BLYS44
BGLN50
BPRO64
BGLU86
BASP87
BHOH425
BHOH436

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCNVDH
ChainResidueDetails
ATYR206-HIS212

226707

PDB entries from 2024-10-30

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