6WD4

Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure II-B2)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
8	0003723	molecular_function	RNA binding
8	0003746	molecular_function	translation elongation factor activity
8	0003924	molecular_function	GTPase activity
8	0005515	molecular_function	protein binding
8	0005525	molecular_function	GTP binding
8	0005737	cellular_component	cytoplasm
8	0005886	cellular_component	plasma membrane
8	0006412	biological_process	translation
8	0006414	biological_process	translational elongation
8	0032045	cellular_component	guanyl-nucleotide exchange factor complex
8	0046677	biological_process	response to antibiotic
8	0097216	molecular_function	guanosine tetraphosphate binding
B	0000027	biological_process	ribosomal large subunit assembly
B	0000302	biological_process	response to reactive oxygen species
B	0002181	biological_process	cytoplasmic translation
B	0003735	molecular_function	structural constituent of ribosome
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0009314	biological_process	response to radiation
B	0015934	cellular_component	large ribosomal subunit
B	0022625	cellular_component	cytosolic large ribosomal subunit
B	1990904	cellular_component	ribonucleoprotein complex
C	0000027	biological_process	ribosomal large subunit assembly
C	0000049	molecular_function	tRNA binding
C	0002181	biological_process	cytoplasmic translation
C	0003735	molecular_function	structural constituent of ribosome
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0022625	cellular_component	cytosolic large ribosomal subunit
C	0046677	biological_process	response to antibiotic
C	1990904	cellular_component	ribonucleoprotein complex
D	0002181	biological_process	cytoplasmic translation
D	0003735	molecular_function	structural constituent of ribosome
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0022625	cellular_component	cytosolic large ribosomal subunit
D	1990904	cellular_component	ribonucleoprotein complex
E	0002181	biological_process	cytoplasmic translation
E	0003735	molecular_function	structural constituent of ribosome
E	0005737	cellular_component	cytoplasm
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0022625	cellular_component	cytosolic large ribosomal subunit
E	1990904	cellular_component	ribonucleoprotein complex
F	0002181	biological_process	cytoplasmic translation
F	0003735	molecular_function	structural constituent of ribosome
F	0005737	cellular_component	cytoplasm
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0022625	cellular_component	cytosolic large ribosomal subunit
F	1990904	cellular_component	ribonucleoprotein complex
G	0000028	biological_process	ribosomal small subunit assembly
G	0002181	biological_process	cytoplasmic translation
G	0003735	molecular_function	structural constituent of ribosome
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0008270	molecular_function	zinc ion binding
G	0015935	cellular_component	small ribosomal subunit
G	0022627	cellular_component	cytosolic small ribosomal subunit
G	1990904	cellular_component	ribonucleoprotein complex
H	0003676	molecular_function	nucleic acid binding
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0006412	biological_process	translation
I	0000028	biological_process	ribosomal small subunit assembly
I	0000900	molecular_function	mRNA regulatory element binding translation repressor activity
I	0002181	biological_process	cytoplasmic translation
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005840	cellular_component	ribosome
I	0006353	biological_process	DNA-templated transcription termination
I	0006412	biological_process	translation
I	0006417	biological_process	regulation of translation
I	0015935	cellular_component	small ribosomal subunit
I	0019843	molecular_function	rRNA binding
I	0022627	cellular_component	cytosolic small ribosomal subunit
I	0031564	biological_process	transcription antitermination
I	0042254	biological_process	ribosome biogenesis
I	0042274	biological_process	ribosomal small subunit biogenesis
I	0045947	biological_process	negative regulation of translational initiation
I	0046677	biological_process	response to antibiotic
I	0048027	molecular_function	mRNA 5'-UTR binding
I	1990145	biological_process	maintenance of translational fidelity
I	1990904	cellular_component	ribonucleoprotein complex
J	0000028	biological_process	ribosomal small subunit assembly
J	0002181	biological_process	cytoplasmic translation
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0015935	cellular_component	small ribosomal subunit
J	0019843	molecular_function	rRNA binding
J	0022627	cellular_component	cytosolic small ribosomal subunit
J	0046677	biological_process	response to antibiotic
J	1990145	biological_process	maintenance of translational fidelity
J	1990904	cellular_component	ribonucleoprotein complex
K	0003735	molecular_function	structural constituent of ribosome
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0019843	molecular_function	rRNA binding
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0006412	biological_process	translation
L	0015935	cellular_component	small ribosomal subunit
M	0000028	biological_process	ribosomal small subunit assembly
M	0002181	biological_process	cytoplasmic translation
M	0003735	molecular_function	structural constituent of ribosome
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0006417	biological_process	regulation of translation
M	0019843	molecular_function	rRNA binding
M	0022627	cellular_component	cytosolic small ribosomal subunit
M	0043488	biological_process	regulation of mRNA stability
M	1990904	cellular_component	ribonucleoprotein complex
N	0000049	molecular_function	tRNA binding
N	0002181	biological_process	cytoplasmic translation
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	1990904	cellular_component	ribonucleoprotein complex
O	0000049	molecular_function	tRNA binding
O	0001072	molecular_function	transcription antitermination factor activity, RNA binding
O	0002181	biological_process	cytoplasmic translation
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005515	molecular_function	protein binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0008023	cellular_component	transcription elongation factor complex
O	0015935	cellular_component	small ribosomal subunit
O	0022627	cellular_component	cytosolic small ribosomal subunit
O	0031564	biological_process	transcription antitermination
O	0032784	biological_process	regulation of DNA-templated transcription elongation
O	0042254	biological_process	ribosome biogenesis
O	1990904	cellular_component	ribonucleoprotein complex
P	0002181	biological_process	cytoplasmic translation
P	0003735	molecular_function	structural constituent of ribosome
P	0005515	molecular_function	protein binding
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0019843	molecular_function	rRNA binding
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	0070181	molecular_function	small ribosomal subunit rRNA binding
P	1990904	cellular_component	ribonucleoprotein complex
Q	0000049	molecular_function	tRNA binding
Q	0000372	biological_process	Group I intron splicing
Q	0002181	biological_process	cytoplasmic translation
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005515	molecular_function	protein binding
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0015935	cellular_component	small ribosomal subunit
Q	0019843	molecular_function	rRNA binding
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	0033120	biological_process	positive regulation of RNA splicing
Q	0034336	molecular_function	misfolded RNA binding
Q	0034337	biological_process	RNA folding
Q	0046677	biological_process	response to antibiotic
Q	1990145	biological_process	maintenance of translational fidelity
Q	1990904	cellular_component	ribonucleoprotein complex
R	0000049	molecular_function	tRNA binding
R	0002181	biological_process	cytoplasmic translation
R	0003676	molecular_function	nucleic acid binding
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005515	molecular_function	protein binding
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0015935	cellular_component	small ribosomal subunit
R	0019843	molecular_function	rRNA binding
R	0022627	cellular_component	cytosolic small ribosomal subunit
R	1990904	cellular_component	ribonucleoprotein complex
S	0000028	biological_process	ribosomal small subunit assembly
S	0000049	molecular_function	tRNA binding
S	0002181	biological_process	cytoplasmic translation
S	0003735	molecular_function	structural constituent of ribosome
S	0005737	cellular_component	cytoplasm
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015935	cellular_component	small ribosomal subunit
S	0019843	molecular_function	rRNA binding
S	0022627	cellular_component	cytosolic small ribosomal subunit
S	1990904	cellular_component	ribonucleoprotein complex
T	0000028	biological_process	ribosomal small subunit assembly
T	0002181	biological_process	cytoplasmic translation
T	0003735	molecular_function	structural constituent of ribosome
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0006417	biological_process	regulation of translation
T	0019843	molecular_function	rRNA binding
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	0070181	molecular_function	small ribosomal subunit rRNA binding
T	1990904	cellular_component	ribonucleoprotein complex
U	0000028	biological_process	ribosomal small subunit assembly
U	0000400	molecular_function	four-way junction DNA binding
U	0002181	biological_process	cytoplasmic translation
U	0003735	molecular_function	structural constituent of ribosome
U	0004519	molecular_function	endonuclease activity
U	0004520	molecular_function	DNA endonuclease activity
U	0005737	cellular_component	cytoplasm
U	0005840	cellular_component	ribosome
U	0006259	biological_process	DNA metabolic process
U	0006412	biological_process	translation
U	0015935	cellular_component	small ribosomal subunit
U	0022627	cellular_component	cytosolic small ribosomal subunit
U	1990904	cellular_component	ribonucleoprotein complex
V	0000028	biological_process	ribosomal small subunit assembly
V	0002181	biological_process	cytoplasmic translation
V	0003735	molecular_function	structural constituent of ribosome
V	0005737	cellular_component	cytoplasm
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0008270	molecular_function	zinc ion binding
V	0019843	molecular_function	rRNA binding
V	0022627	cellular_component	cytosolic small ribosomal subunit
V	0046677	biological_process	response to antibiotic
V	0070181	molecular_function	small ribosomal subunit rRNA binding
V	1990904	cellular_component	ribonucleoprotein complex
W	0003735	molecular_function	structural constituent of ribosome
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0015935	cellular_component	small ribosomal subunit
Y	0000028	biological_process	ribosomal small subunit assembly
Y	0002181	biological_process	cytoplasmic translation
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0008073	molecular_function	ornithine decarboxylase inhibitor activity
Y	0015935	cellular_component	small ribosomal subunit
Y	0019843	molecular_function	rRNA binding
Y	0022627	cellular_component	cytosolic small ribosomal subunit
Y	0070181	molecular_function	small ribosomal subunit rRNA binding
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0000028	biological_process	ribosomal small subunit assembly
Z	0002181	biological_process	cytoplasmic translation
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0019843	molecular_function	rRNA binding
Z	0022627	cellular_component	cytosolic small ribosomal subunit
Z	1990904	cellular_component	ribonucleoprotein complex
a	0000027	biological_process	ribosomal large subunit assembly
a	0000049	molecular_function	tRNA binding
a	0002181	biological_process	cytoplasmic translation
a	0003723	molecular_function	RNA binding
a	0003735	molecular_function	structural constituent of ribosome
a	0005515	molecular_function	protein binding
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
a	0006417	biological_process	regulation of translation
a	0015934	cellular_component	large ribosomal subunit
a	0019843	molecular_function	rRNA binding
a	0022625	cellular_component	cytosolic large ribosomal subunit
a	0045947	biological_process	negative regulation of translational initiation
a	1990904	cellular_component	ribonucleoprotein complex
b	0000027	biological_process	ribosomal large subunit assembly
b	0002181	biological_process	cytoplasmic translation
b	0003723	molecular_function	RNA binding
b	0003735	molecular_function	structural constituent of ribosome
b	0005515	molecular_function	protein binding
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0008270	molecular_function	zinc ion binding
b	0015934	cellular_component	large ribosomal subunit
b	0016740	molecular_function	transferase activity
b	0019843	molecular_function	rRNA binding
b	0022625	cellular_component	cytosolic large ribosomal subunit
b	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
b	1990082	cellular_component	DnaA-L2 complex
b	1990904	cellular_component	ribonucleoprotein complex
c	0000027	biological_process	ribosomal large subunit assembly
c	0002181	biological_process	cytoplasmic translation
c	0003735	molecular_function	structural constituent of ribosome
c	0005515	molecular_function	protein binding
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0019843	molecular_function	rRNA binding
c	0022625	cellular_component	cytosolic large ribosomal subunit
c	1990904	cellular_component	ribonucleoprotein complex
d	0001070	molecular_function	RNA-binding transcription regulator activity
d	0002181	biological_process	cytoplasmic translation
d	0003677	molecular_function	DNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0005515	molecular_function	protein binding
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0006353	biological_process	DNA-templated transcription termination
d	0006412	biological_process	translation
d	0006417	biological_process	regulation of translation
d	0015934	cellular_component	large ribosomal subunit
d	0017148	biological_process	negative regulation of translation
d	0019843	molecular_function	rRNA binding
d	0022625	cellular_component	cytosolic large ribosomal subunit
d	0030371	molecular_function	translation repressor activity
d	0031555	biological_process	transcriptional attenuation
d	0042255	biological_process	ribosome assembly
d	0045892	biological_process	negative regulation of DNA-templated transcription
d	0046677	biological_process	response to antibiotic
d	0048027	molecular_function	mRNA 5'-UTR binding
d	0060698	molecular_function	endoribonuclease inhibitor activity
d	1990904	cellular_component	ribonucleoprotein complex
d	2000766	biological_process	negative regulation of cytoplasmic translation
e	0000027	biological_process	ribosomal large subunit assembly
e	0000049	molecular_function	tRNA binding
e	0002181	biological_process	cytoplasmic translation
e	0003723	molecular_function	RNA binding
e	0003735	molecular_function	structural constituent of ribosome
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
e	0008097	molecular_function	5S rRNA binding
e	0019843	molecular_function	rRNA binding
e	0022625	cellular_component	cytosolic large ribosomal subunit
e	1990904	cellular_component	ribonucleoprotein complex
f	0000027	biological_process	ribosomal large subunit assembly
f	0002181	biological_process	cytoplasmic translation
f	0003735	molecular_function	structural constituent of ribosome
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
f	0019843	molecular_function	rRNA binding
f	0022625	cellular_component	cytosolic large ribosomal subunit
f	0046677	biological_process	response to antibiotic
f	0070180	molecular_function	large ribosomal subunit rRNA binding
f	1990904	cellular_component	ribonucleoprotein complex
g	0002181	biological_process	cytoplasmic translation
g	0003735	molecular_function	structural constituent of ribosome
g	0005515	molecular_function	protein binding
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0019843	molecular_function	rRNA binding
g	0022625	cellular_component	cytosolic large ribosomal subunit
g	0070180	molecular_function	large ribosomal subunit rRNA binding
g	1990904	cellular_component	ribonucleoprotein complex
h	0003735	molecular_function	structural constituent of ribosome
h	0006412	biological_process	translation
h	0015934	cellular_component	large ribosomal subunit
i	0000027	biological_process	ribosomal large subunit assembly
i	0002181	biological_process	cytoplasmic translation
i	0003735	molecular_function	structural constituent of ribosome
i	0005515	molecular_function	protein binding
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0005840	cellular_component	ribosome
i	0006412	biological_process	translation
i	0006415	biological_process	translational termination
i	0015968	biological_process	stringent response
i	0019843	molecular_function	rRNA binding
i	0022625	cellular_component	cytosolic large ribosomal subunit
i	0070180	molecular_function	large ribosomal subunit rRNA binding
i	1990904	cellular_component	ribonucleoprotein complex
j	0002181	biological_process	cytoplasmic translation
j	0003729	molecular_function	mRNA binding
j	0003735	molecular_function	structural constituent of ribosome
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005840	cellular_component	ribosome
j	0006412	biological_process	translation
j	0008270	molecular_function	zinc ion binding
j	0017148	biological_process	negative regulation of translation
j	0022625	cellular_component	cytosolic large ribosomal subunit
j	0048027	molecular_function	mRNA 5'-UTR binding
j	0070180	molecular_function	large ribosomal subunit rRNA binding
j	1990904	cellular_component	ribonucleoprotein complex
k	0002181	biological_process	cytoplasmic translation
k	0003735	molecular_function	structural constituent of ribosome
k	0005515	molecular_function	protein binding
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
k	0015934	cellular_component	large ribosomal subunit
k	0019843	molecular_function	rRNA binding
k	0022625	cellular_component	cytosolic large ribosomal subunit
k	0070180	molecular_function	large ribosomal subunit rRNA binding
k	1990904	cellular_component	ribonucleoprotein complex
l	0002181	biological_process	cytoplasmic translation
l	0003735	molecular_function	structural constituent of ribosome
l	0005515	molecular_function	protein binding
l	0005737	cellular_component	cytoplasm
l	0005840	cellular_component	ribosome
l	0006412	biological_process	translation
l	0015934	cellular_component	large ribosomal subunit
l	0019843	molecular_function	rRNA binding
l	0022625	cellular_component	cytosolic large ribosomal subunit
l	1990904	cellular_component	ribonucleoprotein complex
m	0000027	biological_process	ribosomal large subunit assembly
m	0000049	molecular_function	tRNA binding
m	0002181	biological_process	cytoplasmic translation
m	0003735	molecular_function	structural constituent of ribosome
m	0005737	cellular_component	cytoplasm
m	0005840	cellular_component	ribosome
m	0006412	biological_process	translation
m	0019843	molecular_function	rRNA binding
m	0022625	cellular_component	cytosolic large ribosomal subunit
m	1990904	cellular_component	ribonucleoprotein complex
n	0000027	biological_process	ribosomal large subunit assembly
n	0002181	biological_process	cytoplasmic translation
n	0003735	molecular_function	structural constituent of ribosome
n	0005515	molecular_function	protein binding
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0005840	cellular_component	ribosome
n	0006412	biological_process	translation
n	0022625	cellular_component	cytosolic large ribosomal subunit
n	1990904	cellular_component	ribonucleoprotein complex
o	0002181	biological_process	cytoplasmic translation
o	0003735	molecular_function	structural constituent of ribosome
o	0005737	cellular_component	cytoplasm
o	0005829	cellular_component	cytosol
o	0005840	cellular_component	ribosome
o	0006412	biological_process	translation
o	0008097	molecular_function	5S rRNA binding
o	0019843	molecular_function	rRNA binding
o	0022625	cellular_component	cytosolic large ribosomal subunit
o	1990904	cellular_component	ribonucleoprotein complex
p	0000027	biological_process	ribosomal large subunit assembly
p	0002181	biological_process	cytoplasmic translation
p	0003735	molecular_function	structural constituent of ribosome
p	0005737	cellular_component	cytoplasm
p	0005829	cellular_component	cytosol
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation
p	0019843	molecular_function	rRNA binding
p	0022625	cellular_component	cytosolic large ribosomal subunit
p	0070180	molecular_function	large ribosomal subunit rRNA binding
p	1990904	cellular_component	ribonucleoprotein complex
q	0000027	biological_process	ribosomal large subunit assembly
q	0000900	molecular_function	mRNA regulatory element binding translation repressor activity
q	0002181	biological_process	cytoplasmic translation
q	0003729	molecular_function	mRNA binding
q	0003735	molecular_function	structural constituent of ribosome
q	0005737	cellular_component	cytoplasm
q	0005829	cellular_component	cytosol
q	0005840	cellular_component	ribosome
q	0006412	biological_process	translation
q	0017148	biological_process	negative regulation of translation
q	0019843	molecular_function	rRNA binding
q	0022625	cellular_component	cytosolic large ribosomal subunit
q	0070180	molecular_function	large ribosomal subunit rRNA binding
q	1990904	cellular_component	ribonucleoprotein complex
r	0002181	biological_process	cytoplasmic translation
r	0003723	molecular_function	RNA binding
r	0003735	molecular_function	structural constituent of ribosome
r	0005737	cellular_component	cytoplasm
r	0005829	cellular_component	cytosol
r	0005840	cellular_component	ribosome
r	0006412	biological_process	translation
r	0019843	molecular_function	rRNA binding
r	0022625	cellular_component	cytosolic large ribosomal subunit
r	1990904	cellular_component	ribonucleoprotein complex
s	0002181	biological_process	cytoplasmic translation
s	0003735	molecular_function	structural constituent of ribosome
s	0005515	molecular_function	protein binding
s	0005737	cellular_component	cytoplasm
s	0005829	cellular_component	cytosol
s	0005840	cellular_component	ribosome
s	0006412	biological_process	translation
s	0015934	cellular_component	large ribosomal subunit
s	0019843	molecular_function	rRNA binding
s	0022625	cellular_component	cytosolic large ribosomal subunit
s	0042255	biological_process	ribosome assembly
s	0042256	biological_process	cytosolic ribosome assembly
s	0046677	biological_process	response to antibiotic
s	0070180	molecular_function	large ribosomal subunit rRNA binding
s	1902626	biological_process	assembly of large subunit precursor of preribosome
s	1990904	cellular_component	ribonucleoprotein complex
t	0000027	biological_process	ribosomal large subunit assembly
t	0002181	biological_process	cytoplasmic translation
t	0003735	molecular_function	structural constituent of ribosome
t	0005515	molecular_function	protein binding
t	0005737	cellular_component	cytoplasm
t	0005840	cellular_component	ribosome
t	0006412	biological_process	translation
t	0019843	molecular_function	rRNA binding
t	0022625	cellular_component	cytosolic large ribosomal subunit
t	1990904	cellular_component	ribonucleoprotein complex
u	0000027	biological_process	ribosomal large subunit assembly
u	0002181	biological_process	cytoplasmic translation
u	0003723	molecular_function	RNA binding
u	0003735	molecular_function	structural constituent of ribosome
u	0005515	molecular_function	protein binding
u	0005737	cellular_component	cytoplasm
u	0005829	cellular_component	cytosol
u	0005840	cellular_component	ribosome
u	0006412	biological_process	translation
u	0019843	molecular_function	rRNA binding
u	0022625	cellular_component	cytosolic large ribosomal subunit
u	0070180	molecular_function	large ribosomal subunit rRNA binding
u	1990904	cellular_component	ribonucleoprotein complex
v	0000027	biological_process	ribosomal large subunit assembly
v	0002181	biological_process	cytoplasmic translation
v	0003723	molecular_function	RNA binding
v	0003735	molecular_function	structural constituent of ribosome
v	0005737	cellular_component	cytoplasm
v	0005829	cellular_component	cytosol
v	0005840	cellular_component	ribosome
v	0006412	biological_process	translation
v	0008097	molecular_function	5S rRNA binding
v	0009314	biological_process	response to radiation
v	0017148	biological_process	negative regulation of translation
v	0019843	molecular_function	rRNA binding
v	0022625	cellular_component	cytosolic large ribosomal subunit
v	1990904	cellular_component	ribonucleoprotein complex
w	0003735	molecular_function	structural constituent of ribosome
w	0005840	cellular_component	ribosome
w	0006412	biological_process	translation
x	0000027	biological_process	ribosomal large subunit assembly
x	0002181	biological_process	cytoplasmic translation
x	0003735	molecular_function	structural constituent of ribosome
x	0005515	molecular_function	protein binding
x	0005737	cellular_component	cytoplasm
x	0005829	cellular_component	cytosol
x	0005840	cellular_component	ribosome
x	0006412	biological_process	translation
x	0019843	molecular_function	rRNA binding
x	0022625	cellular_component	cytosolic large ribosomal subunit
x	1990904	cellular_component	ribonucleoprotein complex
y	0000027	biological_process	ribosomal large subunit assembly
y	0002181	biological_process	cytoplasmic translation
y	0003735	molecular_function	structural constituent of ribosome
y	0005737	cellular_component	cytoplasm
y	0005840	cellular_component	ribosome
y	0006412	biological_process	translation
y	0019843	molecular_function	rRNA binding
y	0022625	cellular_component	cytosolic large ribosomal subunit
y	1990904	cellular_component	ribonucleoprotein complex
z	0000027	biological_process	ribosomal large subunit assembly
z	0002181	biological_process	cytoplasmic translation
z	0003735	molecular_function	structural constituent of ribosome
z	0005737	cellular_component	cytoplasm
z	0005840	cellular_component	ribosome
z	0006412	biological_process	translation
z	0015934	cellular_component	large ribosomal subunit
z	0022625	cellular_component	cytosolic large ribosomal subunit
z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue FME 5 101

Chain	Residue
1	A2062
1	C2063
1	U2585
5	A76

---

site_id	AC2
Number of Residues	3
Details	binding site for residue PHE 7 101

Chain	Residue
7	A76
8	PHE219
8	PHE262

---

site_id	AC3
Number of Residues	10
Details	binding site for residue GDP 8 501

Chain	Residue
8	GLY24
8	LYS25
8	THR26
8	ASP139
8	MET140
8	SER174
8	ALA175
8	LEU176
8	ASP22
8	HIS23

---

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtkkgvrrp.DGsvirFdgNacVL

Chain	Residue	Details
k	ALA60-LEU86

---

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. SeLlakFVnilmvdGKKstaesIVysA

Chain	Residue	Details
L	SER19-ALA45

---

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GiaVVSTSkGVMtdraAR

Chain	Residue	Details
M	GLY99-ARG116

---

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. IrALnaA.GFrItnitDvTPiPHN

Chain	Residue	Details
P	ILE96-ASN118

---

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR

Chain	Residue	Details
Q	LYS42-ARG49

---

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIrEcRPLS

Chain	Residue	Details
V	GLY55-SER67

---

site_id	PS00057
Number of Residues	24
Details	RIBOSOMAL_S18 Ribosomal protein S18 signature. IDYkd.IatLknYITEs.GKIvpsRI

Chain	Residue	Details
W	ILE20-ILE43

---

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. PdhkhavialTsiYGVGKTRSkAILaAAG

Chain	Residue	Details
R	PRO9-GLY37

---

site_id	PS00301
Number of Residues	16
Details	G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DNapeEKaRGITIntS

Chain	Residue	Details
8	ASP51-SER66

---

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGRqhvpvfVtdemVGhkLGEFapT

Chain	Residue	Details
X	ASN52-THR76

---

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LaaISGQkpLiTkARkS

Chain	Residue	Details
e	LEU56-SER72

---

site_id	PS00359
Number of Residues	16
Details	RIBOSOMAL_L11 Ribosomal protein L11 signature. RsIeGTarSMGlVVeD

Chain	Residue	Details
i	ARG126-ASP141

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGisGQagAirhGiTRAL

Chain	Residue	Details
N	GLY68-LEU86

---

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkrtGAqvrGPIpLPT

Chain	Residue	Details
O	ALA29-THR44

---

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. LqgHFaehKkDhhSrrgLlrMvsqrrkLldY

Chain	Residue	Details
T	LEU38-TYR68

---

site_id	PS00430
Number of Residues	66
Details	TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mireerllkvlraphvsekastameksntivlkvakdatkaeikaavqklfevevevv.........................................................NTLVVKGK

Chain	Residue	Details
t	MET1-LYS66

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KriMpRAkGRadrilkrtSHITVvV

Chain	Residue	Details
s	LYS83-VAL107

---

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGTAmNPvD

Chain	Residue	Details
b	PRO217-ASP228

---

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FadvkkvDvtGtSkGKGfaGtvkR

Chain	Residue	Details
c	PHE101-ARG124

---

site_id	PS00475
Number of Residues	31
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVILaGeVttp..VtVrglrVTkgAraaIeaaG

Chain	Residue	Details
l	LYS109-GLY139

---

site_id	PS00525
Number of Residues	9
Details	RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PEpYKGKGV

Chain	Residue	Details
f	PRO153-VAL161

---

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CrqtgrphgflrkFGLSRiKVR

Chain	Residue	Details
S	ARG62-ARG84

---

site_id	PS00548
Number of Residues	35
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewyreGrVplHt..LradIDyntseahTtyGviG

Chain	Residue	Details
H	ALA162-GLY196

---

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. QSHLLKqVRRDVARV

Chain	Residue	Details
y	GLN39-VAL53

---

site_id	PS00582
Number of Residues	20
Details	RIBOSOMAL_L33 Ribosomal protein L33 signature. YtTtKNkrtkPekLElkKFD

Chain	Residue	Details
C	TYR20-ASP39

---

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRifsFtAltVVGDgn.GrVGfGygkar.EVpa.AI

Chain	Residue	Details
J	GLY27-ILE59

---

site_id	PS00586
Number of Residues	12
Details	RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRqGKIWIRVFP

Chain	Residue	Details
m	LYS58-PRO69

---

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LEgRLdnvVYRmgfGaTraeARqLV

Chain	Residue	Details
I	LEU93-VAL117

---

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. TLlgLgLrRigHtVeredtpairgMInaVsfMV

Chain	Residue	Details
z	THR22-VAL54

---

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ

Chain	Residue	Details
R	ARG86-GLN99

---

site_id	PS00651
Number of Residues	28
Details	RIBOSOMAL_L9 Ribosomal protein L9 signature. GslGdqvnVkaGYarNFLvpqgkAvpaT

Chain	Residue	Details
g	GLY13-THR40

---

site_id	PS00701
Number of Residues	12
Details	RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGkGKGnveyW

Chain	Residue	Details
m	ARG81-TRP92

---

site_id	PS00732
Number of Residues	10
Details	RIBOSOMAL_S16 Ribosomal protein S16 signature. VtIRLARHGA

Chain	Residue	Details
U	VAL2-ALA11

---

site_id	PS00783
Number of Residues	23
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VKGMLPkgpl.GRamfrkLkVYaG

Chain	Residue	Details
j	VAL105-GLY127

---

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpsvlkRnrsh.GFraR

Chain	Residue	Details
D	LYS2-ARG21

---

site_id	PS00828
Number of Residues	27
Details	RIBOSOMAL_L36 Ribosomal protein L36 signature. CrnCkiVkRdgvIrViCsaepKHkQrQ

Chain	Residue	Details
F	CYS11-GLN37

---

site_id	PS00831
Number of Residues	15
Details	RIBOSOMAL_L27 Ribosomal protein L27 signature. GsIIvRQRGtkfhaG

Chain	Residue	Details
w	GLY30-GLY44

---

site_id	PS00936
Number of Residues	27
Details	RIBOSOMAL_L35 Ribosomal protein L35 signature. KTVrGAaKRFkktgkggfkhkhanl.RH

Chain	Residue	Details
E	LYS4-HIS30

---

site_id	PS00937
Number of Residues	17
Details	RIBOSOMAL_L20 Ribosomal protein L20 signature. KrqfRqLWIARINaaaR

Chain	Residue	Details
q	LYS53-ARG69

---

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. MrDMLKAGVHFG

Chain	Residue	Details
G	MET5-GLY16

---

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PdaLFViDadhEhiaIkEannlGIP

Chain	Residue	Details
G	PRO157-PRO181

---

site_id	PS01015
Number of Residues	16
Details	RIBOSOMAL_L19 Ribosomal protein L19 signature. VkRrGAVR.KAKLYYLR

Chain	Residue	Details
p	VAL85-ARG100

---

site_id	PS01048
Number of Residues	10
Details	RIBOSOMAL_S6 Ribosomal protein S6 signature. GrRQLAYpIN

Chain	Residue	Details
K	GLY43-ASN52

---

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeViVLtGkdKGkr.GkV

Chain	Residue	Details
u	ASP7-VAL24

---

site_id	PS01109
Number of Residues	35
Details	RIBOSOMAL_L10 Ribosomal protein L10 signature. KqaIvaeVSevakgalsaVvaDsrGVTVdKMteLR

Chain	Residue	Details
h	LYS8-ARG42

---

site_id	PS01167
Number of Residues	23
Details	RIBOSOMAL_L17 Ribosomal protein L17 signature. IkTTlpKaKelrrvvEpLITlAK

Chain	Residue	Details
n	ILE34-LYS56

---

site_id	PS01169
Number of Residues	23
Details	RIBOSOMAL_L21 Ribosomal protein L21 signature. VkivKfrrRKhyrkqqGHRQwfT

Chain	Residue	Details
r	VAL72-THR94

---

site_id	PS01181
Number of Residues	13
Details	RIBOSOMAL_S21 Ribosomal protein S21 signature. DvALRRFKRsceK

Chain	Residue	Details
Z	ASP12-LYS24

---

site_id	PS01199
Number of Residues	19
Details	RIBOSOMAL_L1 Ribosomal protein L1 signature. MrvVgq.LGqvLGPRGlMPN

Chain	Residue	Details
a	MET121-ASN139

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N,N,N-trimethylalanine => ECO:0000269|PubMed:7004866

Chain	Residue	Details
i	ALA1
h	LYS105
g	LYS112
a	LYS197

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6,N6,N6-trimethyllysine => ECO:0000269|PubMed:7004866

Chain	Residue	Details
i	LYS3
i	LYS39

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: N6-succinyllysine => ECO:0000269|PubMed:21151122

Chain	Residue	Details
i	LYS71
i	LYS80

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:18723842

Chain	Residue	Details
8	LYS314

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000269|PubMed:19150849, ECO:0000269|PubMed:24141193, ECO:0000269|PubMed:8416965

Chain	Residue	Details
8	THR383

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	4
Details	M-CSA 535

Chain	Residue	Details
8	ASP22	electrostatic stabiliser
8	LYS25	electrostatic stabiliser
8	THR26	metal ligand
8	HIS85	electrostatic stabiliser

---