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6WCJ

Asymmetric vertex of the clathrin minicoat cage

Functional Information from GO Data
ChainGOidnamespacecontents
A0000278biological_processmitotic cell cycle
A0005198molecular_functionstructural molecule activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005819cellular_componentspindle
A0005856cellular_componentcytoskeleton
A0005905cellular_componentclathrin-coated pit
A0006886biological_processintracellular protein transport
A0006898biological_processreceptor-mediated endocytosis
A0006914biological_processautophagy
A0016192biological_processvesicle-mediated transport
A0019904molecular_functionprotein domain specific binding
A0030117cellular_componentmembrane coat
A0030130cellular_componentclathrin coat of trans-Golgi network vesicle
A0030132cellular_componentclathrin coat of coated pit
A0030659cellular_componentcytoplasmic vesicle membrane
A0031410cellular_componentcytoplasmic vesicle
A0032051molecular_functionclathrin light chain binding
A0042470cellular_componentmelanosome
A0042802molecular_functionidentical protein binding
A0045334cellular_componentclathrin-coated endocytic vesicle
A0048268biological_processclathrin coat assembly
A0051301biological_processcell division
A0071439cellular_componentclathrin complex
A0072318biological_processclathrin coat disassembly
A0097718molecular_functiondisordered domain specific binding
A1900126biological_processnegative regulation of hyaluronan biosynthetic process
A1990763molecular_functionarrestin family protein binding
B0005198molecular_functionstructural molecule activity
B0005515molecular_functionprotein binding
B0005886cellular_componentplasma membrane
B0005905cellular_componentclathrin-coated pit
B0006886biological_processintracellular protein transport
B0016192biological_processvesicle-mediated transport
B0030118cellular_componentclathrin coat
B0030125cellular_componentclathrin vesicle coat
B0030130cellular_componentclathrin coat of trans-Golgi network vesicle
B0030132cellular_componentclathrin coat of coated pit
B0030659cellular_componentcytoplasmic vesicle membrane
B0030672cellular_componentsynaptic vesicle membrane
B0031410cellular_componentcytoplasmic vesicle
B0032050molecular_functionclathrin heavy chain binding
B0072583biological_processclathrin-dependent endocytosis
B0099631cellular_componentpostsynaptic endocytic zone cytoplasmic component
C0000278biological_processmitotic cell cycle
C0005198molecular_functionstructural molecule activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005819cellular_componentspindle
C0005856cellular_componentcytoskeleton
C0005905cellular_componentclathrin-coated pit
C0006886biological_processintracellular protein transport
C0006898biological_processreceptor-mediated endocytosis
C0006914biological_processautophagy
C0016192biological_processvesicle-mediated transport
C0019904molecular_functionprotein domain specific binding
C0030117cellular_componentmembrane coat
C0030130cellular_componentclathrin coat of trans-Golgi network vesicle
C0030132cellular_componentclathrin coat of coated pit
C0030659cellular_componentcytoplasmic vesicle membrane
C0031410cellular_componentcytoplasmic vesicle
C0032051molecular_functionclathrin light chain binding
C0042470cellular_componentmelanosome
C0042802molecular_functionidentical protein binding
C0045334cellular_componentclathrin-coated endocytic vesicle
C0048268biological_processclathrin coat assembly
C0051301biological_processcell division
C0071439cellular_componentclathrin complex
C0072318biological_processclathrin coat disassembly
C0097718molecular_functiondisordered domain specific binding
C1900126biological_processnegative regulation of hyaluronan biosynthetic process
C1990763molecular_functionarrestin family protein binding
D0000278biological_processmitotic cell cycle
D0005198molecular_functionstructural molecule activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005819cellular_componentspindle
D0005856cellular_componentcytoskeleton
D0005905cellular_componentclathrin-coated pit
D0006886biological_processintracellular protein transport
D0006898biological_processreceptor-mediated endocytosis
D0006914biological_processautophagy
D0016192biological_processvesicle-mediated transport
D0019904molecular_functionprotein domain specific binding
D0030117cellular_componentmembrane coat
D0030130cellular_componentclathrin coat of trans-Golgi network vesicle
D0030132cellular_componentclathrin coat of coated pit
D0030659cellular_componentcytoplasmic vesicle membrane
D0031410cellular_componentcytoplasmic vesicle
D0032051molecular_functionclathrin light chain binding
D0042470cellular_componentmelanosome
D0042802molecular_functionidentical protein binding
D0045334cellular_componentclathrin-coated endocytic vesicle
D0048268biological_processclathrin coat assembly
D0051301biological_processcell division
D0071439cellular_componentclathrin complex
D0072318biological_processclathrin coat disassembly
D0097718molecular_functiondisordered domain specific binding
D1900126biological_processnegative regulation of hyaluronan biosynthetic process
D1990763molecular_functionarrestin family protein binding
E0005198molecular_functionstructural molecule activity
E0005515molecular_functionprotein binding
E0005886cellular_componentplasma membrane
E0005905cellular_componentclathrin-coated pit
E0006886biological_processintracellular protein transport
E0016192biological_processvesicle-mediated transport
E0030118cellular_componentclathrin coat
E0030125cellular_componentclathrin vesicle coat
E0030130cellular_componentclathrin coat of trans-Golgi network vesicle
E0030132cellular_componentclathrin coat of coated pit
E0030659cellular_componentcytoplasmic vesicle membrane
E0030672cellular_componentsynaptic vesicle membrane
E0031410cellular_componentcytoplasmic vesicle
E0032050molecular_functionclathrin heavy chain binding
E0072583biological_processclathrin-dependent endocytosis
E0099631cellular_componentpostsynaptic endocytic zone cytoplasmic component
F0005198molecular_functionstructural molecule activity
F0005515molecular_functionprotein binding
F0005886cellular_componentplasma membrane
F0005905cellular_componentclathrin-coated pit
F0006886biological_processintracellular protein transport
F0016192biological_processvesicle-mediated transport
F0030118cellular_componentclathrin coat
F0030125cellular_componentclathrin vesicle coat
F0030130cellular_componentclathrin coat of trans-Golgi network vesicle
F0030132cellular_componentclathrin coat of coated pit
F0030659cellular_componentcytoplasmic vesicle membrane
F0030672cellular_componentsynaptic vesicle membrane
F0031410cellular_componentcytoplasmic vesicle
F0032050molecular_functionclathrin heavy chain binding
F0072583biological_processclathrin-dependent endocytosis
F0099631cellular_componentpostsynaptic endocytic zone cytoplasmic component
G0000278biological_processmitotic cell cycle
G0005198molecular_functionstructural molecule activity
G0005515molecular_functionprotein binding
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005819cellular_componentspindle
G0005856cellular_componentcytoskeleton
G0005905cellular_componentclathrin-coated pit
G0006886biological_processintracellular protein transport
G0006898biological_processreceptor-mediated endocytosis
G0006914biological_processautophagy
G0016192biological_processvesicle-mediated transport
G0019904molecular_functionprotein domain specific binding
G0030117cellular_componentmembrane coat
G0030130cellular_componentclathrin coat of trans-Golgi network vesicle
G0030132cellular_componentclathrin coat of coated pit
G0030659cellular_componentcytoplasmic vesicle membrane
G0031410cellular_componentcytoplasmic vesicle
G0032051molecular_functionclathrin light chain binding
G0042470cellular_componentmelanosome
G0042802molecular_functionidentical protein binding
G0045334cellular_componentclathrin-coated endocytic vesicle
G0048268biological_processclathrin coat assembly
G0051301biological_processcell division
G0071439cellular_componentclathrin complex
G0072318biological_processclathrin coat disassembly
G0097718molecular_functiondisordered domain specific binding
G1900126biological_processnegative regulation of hyaluronan biosynthetic process
G1990763molecular_functionarrestin family protein binding
H0000278biological_processmitotic cell cycle
H0005198molecular_functionstructural molecule activity
H0005515molecular_functionprotein binding
H0005737cellular_componentcytoplasm
H0005739cellular_componentmitochondrion
H0005819cellular_componentspindle
H0005856cellular_componentcytoskeleton
H0005905cellular_componentclathrin-coated pit
H0006886biological_processintracellular protein transport
H0006898biological_processreceptor-mediated endocytosis
H0006914biological_processautophagy
H0016192biological_processvesicle-mediated transport
H0019904molecular_functionprotein domain specific binding
H0030117cellular_componentmembrane coat
H0030130cellular_componentclathrin coat of trans-Golgi network vesicle
H0030132cellular_componentclathrin coat of coated pit
H0030659cellular_componentcytoplasmic vesicle membrane
H0031410cellular_componentcytoplasmic vesicle
H0032051molecular_functionclathrin light chain binding
H0042470cellular_componentmelanosome
H0042802molecular_functionidentical protein binding
H0045334cellular_componentclathrin-coated endocytic vesicle
H0048268biological_processclathrin coat assembly
H0051301biological_processcell division
H0071439cellular_componentclathrin complex
H0072318biological_processclathrin coat disassembly
H0097718molecular_functiondisordered domain specific binding
H1900126biological_processnegative regulation of hyaluronan biosynthetic process
H1990763molecular_functionarrestin family protein binding
I0000278biological_processmitotic cell cycle
I0005198molecular_functionstructural molecule activity
I0005515molecular_functionprotein binding
I0005737cellular_componentcytoplasm
I0005739cellular_componentmitochondrion
I0005819cellular_componentspindle
I0005856cellular_componentcytoskeleton
I0005905cellular_componentclathrin-coated pit
I0006886biological_processintracellular protein transport
I0006898biological_processreceptor-mediated endocytosis
I0006914biological_processautophagy
I0016192biological_processvesicle-mediated transport
I0019904molecular_functionprotein domain specific binding
I0030117cellular_componentmembrane coat
I0030130cellular_componentclathrin coat of trans-Golgi network vesicle
I0030132cellular_componentclathrin coat of coated pit
I0030659cellular_componentcytoplasmic vesicle membrane
I0031410cellular_componentcytoplasmic vesicle
I0032051molecular_functionclathrin light chain binding
I0042470cellular_componentmelanosome
I0042802molecular_functionidentical protein binding
I0045334cellular_componentclathrin-coated endocytic vesicle
I0048268biological_processclathrin coat assembly
I0051301biological_processcell division
I0071439cellular_componentclathrin complex
I0072318biological_processclathrin coat disassembly
I0097718molecular_functiondisordered domain specific binding
I1900126biological_processnegative regulation of hyaluronan biosynthetic process
I1990763molecular_functionarrestin family protein binding
J0005198molecular_functionstructural molecule activity
J0005515molecular_functionprotein binding
J0005886cellular_componentplasma membrane
J0005905cellular_componentclathrin-coated pit
J0006886biological_processintracellular protein transport
J0016192biological_processvesicle-mediated transport
J0030118cellular_componentclathrin coat
J0030125cellular_componentclathrin vesicle coat
J0030130cellular_componentclathrin coat of trans-Golgi network vesicle
J0030132cellular_componentclathrin coat of coated pit
J0030659cellular_componentcytoplasmic vesicle membrane
J0030672cellular_componentsynaptic vesicle membrane
J0031410cellular_componentcytoplasmic vesicle
J0032050molecular_functionclathrin heavy chain binding
J0072583biological_processclathrin-dependent endocytosis
J0099631cellular_componentpostsynaptic endocytic zone cytoplasmic component
K0000278biological_processmitotic cell cycle
K0005198molecular_functionstructural molecule activity
K0005515molecular_functionprotein binding
K0005737cellular_componentcytoplasm
K0005739cellular_componentmitochondrion
K0005819cellular_componentspindle
K0005856cellular_componentcytoskeleton
K0005905cellular_componentclathrin-coated pit
K0006886biological_processintracellular protein transport
K0006898biological_processreceptor-mediated endocytosis
K0006914biological_processautophagy
K0016192biological_processvesicle-mediated transport
K0019904molecular_functionprotein domain specific binding
K0030117cellular_componentmembrane coat
K0030130cellular_componentclathrin coat of trans-Golgi network vesicle
K0030132cellular_componentclathrin coat of coated pit
K0030659cellular_componentcytoplasmic vesicle membrane
K0031410cellular_componentcytoplasmic vesicle
K0032051molecular_functionclathrin light chain binding
K0042470cellular_componentmelanosome
K0042802molecular_functionidentical protein binding
K0045334cellular_componentclathrin-coated endocytic vesicle
K0048268biological_processclathrin coat assembly
K0051301biological_processcell division
K0071439cellular_componentclathrin complex
K0072318biological_processclathrin coat disassembly
K0097718molecular_functiondisordered domain specific binding
K1900126biological_processnegative regulation of hyaluronan biosynthetic process
K1990763molecular_functionarrestin family protein binding
L0000278biological_processmitotic cell cycle
L0005198molecular_functionstructural molecule activity
L0005515molecular_functionprotein binding
L0005737cellular_componentcytoplasm
L0005739cellular_componentmitochondrion
L0005819cellular_componentspindle
L0005856cellular_componentcytoskeleton
L0005905cellular_componentclathrin-coated pit
L0006886biological_processintracellular protein transport
L0006898biological_processreceptor-mediated endocytosis
L0006914biological_processautophagy
L0016192biological_processvesicle-mediated transport
L0019904molecular_functionprotein domain specific binding
L0030117cellular_componentmembrane coat
L0030130cellular_componentclathrin coat of trans-Golgi network vesicle
L0030132cellular_componentclathrin coat of coated pit
L0030659cellular_componentcytoplasmic vesicle membrane
L0031410cellular_componentcytoplasmic vesicle
L0032051molecular_functionclathrin light chain binding
L0042470cellular_componentmelanosome
L0042802molecular_functionidentical protein binding
L0045334cellular_componentclathrin-coated endocytic vesicle
L0048268biological_processclathrin coat assembly
L0051301biological_processcell division
L0071439cellular_componentclathrin complex
L0072318biological_processclathrin coat disassembly
L0097718molecular_functiondisordered domain specific binding
L1900126biological_processnegative regulation of hyaluronan biosynthetic process
L1990763molecular_functionarrestin family protein binding
M0000278biological_processmitotic cell cycle
M0005198molecular_functionstructural molecule activity
M0005515molecular_functionprotein binding
M0005737cellular_componentcytoplasm
M0005739cellular_componentmitochondrion
M0005819cellular_componentspindle
M0005856cellular_componentcytoskeleton
M0005905cellular_componentclathrin-coated pit
M0006886biological_processintracellular protein transport
M0006898biological_processreceptor-mediated endocytosis
M0006914biological_processautophagy
M0016192biological_processvesicle-mediated transport
M0019904molecular_functionprotein domain specific binding
M0030117cellular_componentmembrane coat
M0030130cellular_componentclathrin coat of trans-Golgi network vesicle
M0030132cellular_componentclathrin coat of coated pit
M0030659cellular_componentcytoplasmic vesicle membrane
M0031410cellular_componentcytoplasmic vesicle
M0032051molecular_functionclathrin light chain binding
M0042470cellular_componentmelanosome
M0042802molecular_functionidentical protein binding
M0045334cellular_componentclathrin-coated endocytic vesicle
M0048268biological_processclathrin coat assembly
M0051301biological_processcell division
M0071439cellular_componentclathrin complex
M0072318biological_processclathrin coat disassembly
M0097718molecular_functiondisordered domain specific binding
M1900126biological_processnegative regulation of hyaluronan biosynthetic process
M1990763molecular_functionarrestin family protein binding
N0005198molecular_functionstructural molecule activity
N0005515molecular_functionprotein binding
N0005886cellular_componentplasma membrane
N0005905cellular_componentclathrin-coated pit
N0006886biological_processintracellular protein transport
N0016192biological_processvesicle-mediated transport
N0030118cellular_componentclathrin coat
N0030125cellular_componentclathrin vesicle coat
N0030130cellular_componentclathrin coat of trans-Golgi network vesicle
N0030132cellular_componentclathrin coat of coated pit
N0030659cellular_componentcytoplasmic vesicle membrane
N0030672cellular_componentsynaptic vesicle membrane
N0031410cellular_componentcytoplasmic vesicle
N0032050molecular_functionclathrin heavy chain binding
N0072583biological_processclathrin-dependent endocytosis
N0099631cellular_componentpostsynaptic endocytic zone cytoplasmic component
O0005198molecular_functionstructural molecule activity
O0005515molecular_functionprotein binding
O0005886cellular_componentplasma membrane
O0005905cellular_componentclathrin-coated pit
O0006886biological_processintracellular protein transport
O0016192biological_processvesicle-mediated transport
O0030118cellular_componentclathrin coat
O0030125cellular_componentclathrin vesicle coat
O0030130cellular_componentclathrin coat of trans-Golgi network vesicle
O0030132cellular_componentclathrin coat of coated pit
O0030659cellular_componentcytoplasmic vesicle membrane
O0030672cellular_componentsynaptic vesicle membrane
O0031410cellular_componentcytoplasmic vesicle
O0032050molecular_functionclathrin heavy chain binding
O0072583biological_processclathrin-dependent endocytosis
O0099631cellular_componentpostsynaptic endocytic zone cytoplasmic component
Functional Information from PROSITE/UniProt
site_idPS00224
Number of Residues7
DetailsCLATHRIN_LIGHT_CHN_1 Clathrin light chain signature 1. FLAQQES
ChainResidueDetails
BPHE27-SER33

site_idPS00581
Number of Residues14
DetailsCLATHRIN_LIGHT_CHN_2 Clathrin light chain signature 2. KDvSRLRsVLMsLK
ChainResidueDetails
BLYS209-LYS222

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsMOD_RES: Blocked amino end (Met)
ChainResidueDetails
BMET1
EMET1
FMET1
OMET1
JMET1
NMET1
HALA2
IALA2
KALA2

site_idSWS_FT_FI2
Number of Residues12
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:3128543
ChainResidueDetails
BSER11
JSER13
NSER11
NSER13
MSER67
MSER1229
MSER1494
GSER67
GSER1229
GSER1494
HSER67
BSER13
HSER1229
HSER1494
ISER67
ISER1229
ISER1494
KSER67
KSER1229
KSER1494
ESER11
ESER13
FSER11
FSER13
OSER11
OSER13
JSER11

site_idSWS_FT_FI3
Number of Residues6
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P09497
ChainResidueDetails
BTHR186
ETHR186
FTHR186
OTHR186
JTHR186
NTHR186
HTHR105
ITHR105
KTHR105

site_idSWS_FT_FI4
Number of Residues6
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q6IRU5
ChainResidueDetails
BLYS203
DTYR899
DTYR1206
DTYR1487
LTYR184
LTYR899
LTYR1206
LTYR1487
MTYR184
MTYR899
MTYR1206
ELYS203
MTYR1487
GTYR184
GTYR899
GTYR1206
GTYR1487
HTYR184
HTYR899
HTYR1206
HTYR1487
ITYR184
FLYS203
ITYR899
ITYR1206
ITYR1487
KTYR184
KTYR899
KTYR1206
KTYR1487
OLYS203
JLYS203
NLYS203
CTYR1206
CTYR1487
DTYR184

site_idSWS_FT_FI5
Number of Residues6
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P09496
ChainResidueDetails
BSER216
ESER216
FSER216
OSER216
JSER216
NSER216
HTHR394
ITHR394
KTHR394

site_idSWS_FT_FI6
Number of Residues18
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:Q00610
ChainResidueDetails
ATYR634
MTYR1477
GTYR634
GTYR1477
HTYR634
HTYR1477
ITYR634
ITYR1477
KTYR634
KTYR1477
ATYR1477
CTYR634
CTYR1477
DTYR634
DTYR1477
LTYR634
LTYR1477
MTYR634

site_idSWS_FT_FI7
Number of Residues9
DetailsMOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q68FD5
ChainResidueDetails
ALYS737
CLYS737
DLYS737
LLYS737
MLYS737
GLYS737
HLYS737
ILYS737
KLYS737

site_idSWS_FT_FI8
Number of Residues18
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q00610
ChainResidueDetails
ALYS856
MLYS1501
GLYS856
GLYS1501
HLYS856
HLYS1501
ILYS856
ILYS1501
KLYS856
KLYS1501
ALYS1501
CLYS856
CLYS1501
DLYS856
DLYS1501
LLYS856
LLYS1501
MLYS856

site_idSWS_FT_FI9
Number of Residues9
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q68FD5
ChainResidueDetails
ASER1167
CSER1167
DSER1167
LSER1167
MSER1167
GSER1167
HSER1167
ISER1167
KSER1167

site_idSWS_FT_FI10
Number of Residues9
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q68FD5
ChainResidueDetails
ALYS1441
CLYS1441
DLYS1441
LLYS1441
MLYS1441
GLYS1441
HLYS1441
ILYS1441
KLYS1441

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PDB entries from 2024-07-17

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