6WC8

HIV Integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0015074	biological_process	DNA integration

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue TQM A 301

Chain	Residue
A	GLN95
A	LYS173
A	THR174
A	GLU96
A	TYR99
A	LEU102
A	ALA128
A	ALA129
A	TRP132
A	GLU170
A	HIS171

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site_id	AC2
Number of Residues	1
Details	binding site for residue IOD A 302

Chain	Residue
A	GLY70

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site_id	AC3
Number of Residues	2
Details	binding site for residue IOD A 303

Chain	Residue
A	LYS71
A	IOD305

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site_id	AC4
Number of Residues	1
Details	binding site for residue IOD A 304

Chain	Residue
A	GLN137

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site_id	AC5
Number of Residues	3
Details	binding site for residue IOD A 305

Chain	Residue
A	LYS71
A	VAL88
A	IOD303

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site_id	AC6
Number of Residues	5
Details	binding site for residue SO4 A 306

Chain	Residue
A	SER81
A	GLY82
A	HIS183
A	ALA196
A	ARG199

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site_id	AC7
Number of Residues	6
Details	binding site for residue SO4 A 307

Chain	Residue
A	PRO109
A	LYS111
A	PHE121
A	THR122
A	LYS127
A	LYS185

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site_id	AC8
Number of Residues	4
Details	binding site for residue SO4 A 308

Chain	Residue
A	THR66
A	HIS67
A	LYS159
A	TYR194

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site_id	AC9
Number of Residues	5
Details	binding site for residue SO4 A 309

Chain	Residue
A	GLY94
A	LYS111
A	SER123
A	THR124
A	THR125

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