6WAC

FF248-249AA PCNA mutant defective in BIR

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000278	biological_process	mitotic cell cycle
A	0000710	biological_process	meiotic mismatch repair
A	0000781	cellular_component	chromosome, telomeric region
A	0003677	molecular_function	DNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005657	cellular_component	replication fork
A	0006260	biological_process	DNA replication
A	0006272	biological_process	leading strand elongation
A	0006273	biological_process	lagging strand elongation
A	0006275	biological_process	regulation of DNA replication
A	0006281	biological_process	DNA repair
A	0006289	biological_process	nucleotide-excision repair
A	0006298	biological_process	mismatch repair
A	0006301	biological_process	postreplication repair
A	0006974	biological_process	DNA damage response
A	0007064	biological_process	mitotic sister chromatid cohesion
A	0019985	biological_process	translesion synthesis
A	0030337	molecular_function	DNA polymerase processivity factor activity
A	0030466	biological_process	silent mating-type cassette heterochromatin formation
A	0031509	biological_process	subtelomeric heterochromatin formation
A	0034087	biological_process	establishment of mitotic sister chromatid cohesion
A	0035753	biological_process	maintenance of DNA trinucleotide repeats
A	0042802	molecular_function	identical protein binding
A	0043626	cellular_component	PCNA complex
A	0045739	biological_process	positive regulation of DNA repair
A	0045740	biological_process	positive regulation of DNA replication
A	0051054	biological_process	positive regulation of DNA metabolic process
A	0070987	biological_process	error-free translesion synthesis

Functional Information from PROSITE/UniProt

site_id	PS00293
Number of Residues	19
Details	PCNA_2 Proliferating cell nuclear antigen signature 2. RCDHpvtLgmdLtSLsKIL

Chain	Residue	Details
A	ARG61-LEU79

---

site_id	PS01251
Number of Residues	24
Details	PCNA_1 Proliferating cell nuclear antigen signature 1. GIiAqAVDdSRVlLVsLeIgveaF

Chain	Residue	Details
A	GLY34-PHE57

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	19
Details	DNA binding: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"PubMed","id":"15166219","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"12226657","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---