Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue FLC M 101 |
| Chain | Residue |
| A | HIS99 |
| M | HOH209 |
| M | HOH213 |
| M | HOH215 |
| M | HOH226 |
| A | ASP100 |
| A | HIS105 |
| M | THR7 |
| M | THR9 |
| M | GLU34 |
| M | ILE36 |
| M | LEU71 |
| M | HOH208 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue FLC N 101 |
| Chain | Residue |
| B | HIS99 |
| B | ASP100 |
| B | GLY103 |
| B | HIS105 |
| N | THR7 |
| N | THR9 |
| N | GLU34 |
| N | ILE36 |
| N | LEU71 |
| N | HOH205 |
| N | HOH210 |
| N | HOH216 |
| N | HOH226 |
| N | HOH229 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue FLC O 101 |
| Chain | Residue |
| F | HIS99 |
| F | ASP100 |
| F | HIS105 |
| O | THR9 |
| O | GLU34 |
| O | ILE36 |
| O | LEU71 |
| O | HOH3709 |
| O | HOH3710 |
| O | HOH3711 |
| O | HOH3715 |
| O | HOH3735 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue FLC P 101 |
| Chain | Residue |
| D | HIS99 |
| D | ASP100 |
| D | HIS105 |
| P | LYS11 |
| P | GLU34 |
| P | ILE36 |
| P | LEU71 |
| P | HOH208 |
| P | HOH220 |
| P | HOH227 |
| P | HOH228 |
| P | HOH233 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | binding site for residue FLC Q 101 |
| Chain | Residue |
| I | HIS99 |
| I | ASP100 |
| I | HIS105 |
| Q | THR7 |
| Q | LYS11 |
| Q | GLU34 |
| Q | ILE36 |
| Q | LEU71 |
| Q | HOH206 |
| Q | HOH208 |
| Q | HOH210 |
| Q | HOH211 |
| Q | HOH217 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue FLC R 101 |
| Chain | Residue |
| J | HIS99 |
| J | ASP100 |
| J | ASN101 |
| J | HIS105 |
| R | THR7 |
| R | GLU34 |
| R | ILE36 |
| R | LEU71 |
| R | HOH207 |
| R | HOH209 |
| R | HOH220 |
| R | HOH223 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | binding site for residue FLC S 101 |
| Chain | Residue |
| E | HIS99 |
| E | ASP100 |
| E | GLY103 |
| E | HIS105 |
| S | THR7 |
| S | THR9 |
| S | GLU34 |
| S | ILE36 |
| S | LEU71 |
| S | HOH207 |
| S | HOH212 |
| S | HOH216 |
| S | HOH225 |
| S | HOH233 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | binding site for residue FLC T 101 |
| Chain | Residue |
| T | HOH207 |
| T | HOH212 |
| T | HOH221 |
| C | HIS99 |
| C | ASP100 |
| C | GLY103 |
| C | HIS105 |
| T | THR9 |
| T | GLU34 |
| T | ILE36 |
| T | LEU71 |
| T | HOH204 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | binding site for residue FLC U 101 |
| Chain | Residue |
| K | HIS99 |
| K | ASP100 |
| K | HIS105 |
| U | THR7 |
| U | THR9 |
| U | GLU34 |
| U | ILE36 |
| U | LEU71 |
| U | HOH207 |
| U | HOH213 |
| U | HOH214 |
| U | HOH218 |
| U | HOH231 |
| site_id | AD1 |
| Number of Residues | 13 |
| Details | binding site for residue FLC V 101 |
| Chain | Residue |
| L | HIS99 |
| L | ASP100 |
| L | HIS105 |
| V | THR7 |
| V | THR9 |
| V | GLU34 |
| V | ILE36 |
| V | LEU71 |
| V | HOH202 |
| V | HOH210 |
| V | HOH226 |
| V | HOH227 |
| V | HOH249 |
| site_id | AD2 |
| Number of Residues | 14 |
| Details | binding site for residue FLC W 101 |
| Chain | Residue |
| G | HIS99 |
| G | ASP100 |
| G | HIS105 |
| G | HOH332 |
| W | THR7 |
| W | THR9 |
| W | ILE13 |
| W | GLU34 |
| W | ILE36 |
| W | LEU71 |
| W | HOH205 |
| W | HOH211 |
| W | HOH216 |
| W | HOH219 |
| site_id | AD3 |
| Number of Residues | 13 |
| Details | binding site for residue FLC X 101 |
| Chain | Residue |
| H | HIS99 |
| H | ASP100 |
| H | GLY103 |
| H | HIS105 |
| H | HOH364 |
| X | THR7 |
| X | GLU34 |
| X | ILE36 |
| X | LEU71 |
| X | HOH205 |
| X | HOH211 |
| X | HOH212 |
| X | HOH233 |
| site_id | AD4 |
| Number of Residues | 30 |
| Details | binding site for Di-peptide CYS A 53 and NEH M 76 |
| Chain | Residue |
| A | ILE48 |
| A | ASN50 |
| A | GLY51 |
| A | SER52 |
| A | PHE54 |
| A | PHE55 |
| A | ASP56 |
| A | SER57 |
| A | ALA72 |
| A | GLU73 |
| A | LYS74 |
| A | LEU75 |
| A | ASN77 |
| A | ASP78 |
| A | CYS79 |
| A | ARG80 |
| A | ILE117 |
| A | MET118 |
| A | ARG119 |
| A | ASN120 |
| A | ARG122 |
| A | TRP123 |
| A | LEU190 |
| A | HIS191 |
| A | PHE192 |
| M | GLU24 |
| M | GLU51 |
| M | ASP52 |
| M | ARG54 |
| M | GLY75 |
| site_id | AD5 |
| Number of Residues | 31 |
| Details | binding site for Di-peptide CYS B 53 and NEH N 76 |
| Chain | Residue |
| B | ILE48 |
| B | ASN50 |
| B | GLY51 |
| B | SER52 |
| B | PHE54 |
| B | PHE55 |
| B | ASP56 |
| B | SER57 |
| B | ALA72 |
| B | GLU73 |
| B | LYS74 |
| B | LEU75 |
| B | ASN77 |
| B | ASP78 |
| B | CYS79 |
| B | ARG80 |
| B | ILE117 |
| B | ARG119 |
| B | ASN120 |
| B | ARG122 |
| B | TRP123 |
| B | LEU190 |
| B | HIS191 |
| B | PHE192 |
| N | GLU24 |
| N | GLU51 |
| N | ASP52 |
| N | ARG54 |
| N | GLY75 |
| N | HOH240 |
| V | HOH222 |
| site_id | AD6 |
| Number of Residues | 31 |
| Details | binding site for Di-peptide CYS C 53 and NEH T 76 |
| Chain | Residue |
| C | ILE48 |
| C | ASN50 |
| C | GLY51 |
| C | SER52 |
| C | PHE54 |
| C | PHE55 |
| C | ASP56 |
| C | SER57 |
| C | ALA72 |
| C | GLU73 |
| C | LYS74 |
| C | LEU75 |
| C | ASN77 |
| C | ASP78 |
| C | CYS79 |
| C | ARG80 |
| C | ILE117 |
| C | ARG119 |
| C | ASN120 |
| C | ARG122 |
| C | TRP123 |
| C | LEU190 |
| C | HIS191 |
| C | PHE192 |
| T | GLU24 |
| T | GLU51 |
| T | ASP52 |
| T | ARG54 |
| T | GLY75 |
| T | HOH214 |
| T | HOH246 |
| site_id | AD7 |
| Number of Residues | 30 |
| Details | binding site for Di-peptide CYS D 53 and NEH P 76 |
| Chain | Residue |
| D | ILE48 |
| D | ASN50 |
| D | GLY51 |
| D | SER52 |
| D | PHE54 |
| D | PHE55 |
| D | ASP56 |
| D | SER57 |
| D | ALA72 |
| D | GLU73 |
| D | LYS74 |
| D | LEU75 |
| D | ASN77 |
| D | ASP78 |
| D | CYS79 |
| D | ARG80 |
| D | ILE117 |
| D | ARG119 |
| D | ASN120 |
| D | ARG122 |
| D | TRP123 |
| D | LEU190 |
| D | HIS191 |
| D | PHE192 |
| P | GLU24 |
| P | GLU51 |
| P | ASP52 |
| P | ARG54 |
| P | GLY75 |
| P | HOH235 |
| site_id | AD8 |
| Number of Residues | 33 |
| Details | binding site for Di-peptide CYS E 53 and NEH S 76 |
| Chain | Residue |
| E | ILE48 |
| E | ASN50 |
| E | GLY51 |
| E | SER52 |
| E | PHE54 |
| E | PHE55 |
| E | ASP56 |
| E | SER57 |
| E | ALA72 |
| E | GLU73 |
| E | LYS74 |
| E | LEU75 |
| E | ASN77 |
| E | ASP78 |
| E | CYS79 |
| E | ARG80 |
| E | ILE117 |
| E | MET118 |
| E | ARG119 |
| E | ASN120 |
| E | ARG122 |
| E | TRP123 |
| E | LEU190 |
| E | HIS191 |
| E | PHE192 |
| Q | HOH204 |
| S | GLU24 |
| S | GLU51 |
| S | ASP52 |
| S | ARG54 |
| S | GLY75 |
| S | HOH224 |
| S | HOH238 |
| site_id | AD9 |
| Number of Residues | 31 |
| Details | binding site for Di-peptide CYS F 53 and NEH O 76 |
| Chain | Residue |
| F | ILE48 |
| F | ASN50 |
| F | GLY51 |
| F | SER52 |
| F | PHE54 |
| F | PHE55 |
| F | ASP56 |
| F | SER57 |
| F | ALA72 |
| F | GLU73 |
| F | LYS74 |
| F | LEU75 |
| F | ASN77 |
| F | ASP78 |
| F | CYS79 |
| F | ARG80 |
| F | ILE117 |
| F | ARG119 |
| F | ASN120 |
| F | ARG122 |
| F | TRP123 |
| F | LEU190 |
| F | HIS191 |
| F | PHE192 |
| M | HOH218 |
| O | GLU24 |
| O | GLU51 |
| O | ASP52 |
| O | ARG54 |
| O | GLY75 |
| O | HOH3753 |
| site_id | AE1 |
| Number of Residues | 30 |
| Details | binding site for Di-peptide CYS G 53 and NEH W 76 |
| Chain | Residue |
| G | ILE48 |
| G | ASN50 |
| G | GLY51 |
| G | SER52 |
| G | PHE54 |
| G | PHE55 |
| G | ASP56 |
| G | SER57 |
| G | ALA72 |
| G | GLU73 |
| G | LYS74 |
| G | LEU75 |
| G | ASN77 |
| G | ASP78 |
| G | CYS79 |
| G | ARG80 |
| G | ILE117 |
| G | MET118 |
| G | ARG119 |
| G | ASN120 |
| G | ARG122 |
| G | TRP123 |
| G | LEU190 |
| G | HIS191 |
| G | PHE192 |
| W | GLU24 |
| W | GLU51 |
| W | ASP52 |
| W | ARG54 |
| W | GLY75 |
| site_id | AE2 |
| Number of Residues | 30 |
| Details | binding site for Di-peptide CYS H 53 and NEH X 76 |
| Chain | Residue |
| H | ILE48 |
| H | ASN50 |
| H | GLY51 |
| H | SER52 |
| H | PHE54 |
| H | PHE55 |
| H | ASP56 |
| H | SER57 |
| H | ALA72 |
| H | GLU73 |
| H | LYS74 |
| H | LEU75 |
| H | ASN77 |
| H | ASP78 |
| H | CYS79 |
| H | ARG80 |
| H | ILE117 |
| H | MET118 |
| H | ARG119 |
| H | ASN120 |
| H | ARG122 |
| H | TRP123 |
| H | LEU190 |
| H | HIS191 |
| H | PHE192 |
| X | GLU24 |
| X | GLU51 |
| X | ASP52 |
| X | ARG54 |
| X | GLY75 |
| site_id | AE3 |
| Number of Residues | 29 |
| Details | binding site for Di-peptide CYS I 53 and NEH Q 76 |
| Chain | Residue |
| I | ILE48 |
| I | ASN50 |
| I | GLY51 |
| I | SER52 |
| I | PHE54 |
| I | PHE55 |
| I | ASP56 |
| I | SER57 |
| I | ALA72 |
| I | GLU73 |
| I | LYS74 |
| I | LEU75 |
| I | ASN77 |
| I | ASP78 |
| I | CYS79 |
| I | ARG80 |
| I | ILE117 |
| I | ARG119 |
| I | ASN120 |
| I | ARG122 |
| I | TRP123 |
| I | LEU190 |
| I | HIS191 |
| I | PHE192 |
| Q | GLU24 |
| Q | GLU51 |
| Q | ASP52 |
| Q | ARG54 |
| Q | GLY75 |
| site_id | AE4 |
| Number of Residues | 32 |
| Details | binding site for Di-peptide CYS J 53 and NEH R 76 |
| Chain | Residue |
| J | ILE48 |
| J | ASN50 |
| J | GLY51 |
| J | SER52 |
| J | PHE54 |
| J | PHE55 |
| J | ASP56 |
| J | SER57 |
| J | ALA72 |
| J | GLU73 |
| J | LYS74 |
| J | LEU75 |
| J | ASN77 |
| J | ASP78 |
| J | CYS79 |
| J | ARG80 |
| J | ILE117 |
| J | ARG119 |
| J | ASN120 |
| J | ARG122 |
| J | TRP123 |
| J | LEU190 |
| J | HIS191 |
| J | PHE192 |
| R | GLU24 |
| R | GLU51 |
| R | ASP52 |
| R | ARG54 |
| R | GLY75 |
| R | HOH221 |
| R | HOH263 |
| U | HOH225 |
| site_id | AE5 |
| Number of Residues | 29 |
| Details | binding site for Di-peptide CYS K 53 and NEH U 76 |
| Chain | Residue |
| K | ILE48 |
| K | ASN50 |
| K | GLY51 |
| K | SER52 |
| K | PHE54 |
| K | PHE55 |
| K | ASP56 |
| K | SER57 |
| K | ALA72 |
| K | GLU73 |
| K | LYS74 |
| K | LEU75 |
| K | ASN77 |
| K | ASP78 |
| K | CYS79 |
| K | ARG80 |
| K | ILE117 |
| K | MET118 |
| K | ARG119 |
| K | ASN120 |
| K | ARG122 |
| K | TRP123 |
| K | LEU190 |
| K | HIS191 |
| K | PHE192 |
| U | GLU51 |
| U | ASP52 |
| U | ARG54 |
| U | GLY75 |
| site_id | AE6 |
| Number of Residues | 32 |
| Details | binding site for Di-peptide CYS L 53 and NEH V 76 |
| Chain | Residue |
| L | ILE48 |
| L | ASN50 |
| L | GLY51 |
| L | SER52 |
| L | PHE54 |
| L | PHE55 |
| L | ASP56 |
| L | SER57 |
| L | ALA72 |
| L | GLU73 |
| L | LYS74 |
| L | LEU75 |
| L | ASN77 |
| L | ASP78 |
| L | CYS79 |
| L | ARG80 |
| L | ILE117 |
| L | MET118 |
| L | ARG119 |
| L | ASN120 |
| L | ARG122 |
| L | TRP123 |
| L | LEU190 |
| L | HIS191 |
| L | PHE192 |
| L | HOH301 |
| V | GLU24 |
| V | GLU51 |
| V | ASP52 |
| V | ARG54 |
| V | GLY75 |
| V | HOH252 |
| site_id | AE7 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide GLY O 75 and NEH O 76 |
| Chain | Residue |
| F | ASN50 |
| F | CYS53 |
| F | TRP123 |
| F | LEU190 |
| F | PHE192 |
| F | HOH337 |
| F | HOH343 |
| O | ARG74 |
| site_id | AE8 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide GLY P 75 and NEH P 76 |
| Chain | Residue |
| D | ASN50 |
| D | CYS53 |
| D | TRP123 |
| D | LEU190 |
| D | HIS191 |
| D | PHE192 |
| D | HOH332 |
| P | ARG74 |
| P | HOH231 |
| site_id | AE9 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide GLY Q 75 and NEH Q 76 |
| Chain | Residue |
| I | ASN50 |
| I | CYS53 |
| I | TRP123 |
| I | LEU190 |
| I | HIS191 |
| I | PHE192 |
| I | HOH358 |
| I | HOH367 |
| Q | ARG74 |
| site_id | AF1 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide GLY R 75 and NEH R 76 |
| Chain | Residue |
| J | ASN50 |
| J | CYS53 |
| J | TRP123 |
| J | LEU190 |
| J | PHE192 |
| J | HOH348 |
| J | HOH378 |
| R | ARG74 |
| site_id | AF2 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide GLY S 75 and NEH S 76 |
| Chain | Residue |
| E | ASN50 |
| E | CYS53 |
| E | TRP123 |
| E | LEU190 |
| E | HIS191 |
| E | PHE192 |
| E | HOH355 |
| E | HOH356 |
| S | ARG74 |
| site_id | AF3 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide GLY T 75 and NEH T 76 |
| Chain | Residue |
| C | ASN50 |
| C | CYS53 |
| C | TRP123 |
| C | LEU190 |
| C | HIS191 |
| C | PHE192 |
| C | HOH333 |
| C | HOH382 |
| T | ARG74 |
| site_id | AF4 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide GLY U 75 and NEH U 76 |
| Chain | Residue |
| K | ASN50 |
| K | CYS53 |
| K | TRP123 |
| K | LEU190 |
| K | HIS191 |
| K | PHE192 |
| K | HOH328 |
| U | ARG74 |
| U | HOH228 |
| site_id | AF5 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide GLY V 75 and NEH V 76 |
| Chain | Residue |
| L | ASN50 |
| L | CYS53 |
| L | TRP123 |
| L | LEU190 |
| L | PHE192 |
| L | HOH342 |
| V | ARG74 |
| V | HOH235 |
| site_id | AF6 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide GLY W 75 and NEH W 76 |
| Chain | Residue |
| G | ASN50 |
| G | CYS53 |
| G | TRP123 |
| G | LEU190 |
| G | PHE192 |
| G | HOH348 |
| G | HOH355 |
| W | ARG74 |
| site_id | AF7 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide GLY X 75 and NEH X 76 |
| Chain | Residue |
| H | ASN50 |
| H | CYS53 |
| H | TRP123 |
| H | LEU190 |
| H | PHE192 |
| H | HOH366 |
| H | HOH372 |
| X | ARG74 |
Functional Information from PROSITE/UniProt
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| M | LYS27-ASP52 | |
6W9R
