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6W9H

SUBSTITUTED BENZYLOXYTRICYCLIC COMPOUNDS AS RETINOIC ACID-RELATED ORPHAN RECEPTOR GAMMA T AGONISTS

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues16
Detailsbinding site for residue TKJ A 4000
ChainResidue
ACYS285
AARG367
APHE378
ALEU391
AILE397
AILE400
APHE401
AHIS479
AGLN286
ALEU287
ALEU292
AHIS323
ALEU324
AALA327
AMET358
AMET365

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues5
DetailsMotif: {"description":"AF-2"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues4
DetailsMotif: {"description":"LXXLL motif 4"}
ChainResidueDetails

242842

PDB entries from 2025-10-08

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