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6W91

Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments

Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for residue TJP A 201
ChainResidue
AALA22
ATYR114
AALA23
AGLY70
ALEU108
ALEU109
ASER110
ATHR111
AGLY112
AVAL113

site_idAC2
Number of Residues11
Detailsbinding site for residue TJP B 201
ChainResidue
BALA22
BALA23
BALA68
BGLY70
BLEU108
BLEU109
BSER110
BTHR111
BGLY112
BVAL113
BTYR114

site_idAC3
Number of Residues11
Detailsbinding site for residue TJP C 201
ChainResidue
CALA22
CALA23
CALA68
CGLY70
CLEU108
CLEU109
CSER110
CTHR111
CGLY112
CVAL113
CTYR114

site_idAC4
Number of Residues11
Detailsbinding site for residue TJP D 201
ChainResidue
DALA22
DALA23
DALA68
DGLY70
DLEU108
DLEU109
DSER110
DTHR111
DGLY112
DVAL113
DTYR114

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues24
DetailsBINDING: BINDING => ECO:0000269|PubMed:19386706
ChainResidueDetails
AASP10
BGLY112
BVAL113
BTYR114
CASP10
CASN24
CGLY32
CGLY112
CVAL113
CTYR114
DASP10
AASN24
DASN24
DGLY32
DGLY112
DVAL113
DTYR114
AGLY32
AGLY112
AVAL113
ATYR114
BASP10
BASN24
BGLY32

226707

PDB entries from 2024-10-30

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