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6W8T

Crystal structure of metacaspase 4 from Arabidopsis (microcrystals treated with calcium)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004197molecular_functioncysteine-type endopeptidase activity
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006508biological_processproteolysis
A0006952biological_processdefense response
A0008233molecular_functionpeptidase activity
A0008234molecular_functioncysteine-type peptidase activity
A0009506cellular_componentplasmodesma
A0016540biological_processprotein autoprocessing
A0016787molecular_functionhydrolase activity
A0042802molecular_functionidentical protein binding
A0043068biological_processpositive regulation of programmed cell death
B0004197molecular_functioncysteine-type endopeptidase activity
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006508biological_processproteolysis
B0006952biological_processdefense response
B0008233molecular_functionpeptidase activity
B0008234molecular_functioncysteine-type peptidase activity
B0009506cellular_componentplasmodesma
B0016540biological_processprotein autoprocessing
B0016787molecular_functionhydrolase activity
B0042802molecular_functionidentical protein binding
B0043068biological_processpositive regulation of programmed cell death
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue SO4 A 501
ChainResidue
ALYS249
AGLY292
ALYS293
ALEU294

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsActive site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues2
DetailsActive site: {}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues1
DetailsSite: {"description":"Cleavage; by autolysis"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues2
DetailsModified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"UniProtKB","id":"Q9FYE1","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

249697

PDB entries from 2026-02-25

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