6W8S

Crystal structure of metacaspase 4 from Arabidopsis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004197	molecular_function	cysteine-type endopeptidase activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0006952	biological_process	defense response
A	0008233	molecular_function	peptidase activity
A	0008234	molecular_function	cysteine-type peptidase activity
A	0009506	cellular_component	plasmodesma
A	0016540	biological_process	protein autoprocessing
A	0016787	molecular_function	hydrolase activity
A	0042802	molecular_function	identical protein binding
A	0043068	biological_process	positive regulation of programmed cell death
B	0004197	molecular_function	cysteine-type endopeptidase activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006508	biological_process	proteolysis
B	0006952	biological_process	defense response
B	0008233	molecular_function	peptidase activity
B	0008234	molecular_function	cysteine-type peptidase activity
B	0009506	cellular_component	plasmodesma
B	0016540	biological_process	protein autoprocessing
B	0016787	molecular_function	hydrolase activity
B	0042802	molecular_function	identical protein binding
B	0043068	biological_process	positive regulation of programmed cell death
C	0004197	molecular_function	cysteine-type endopeptidase activity
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006508	biological_process	proteolysis
C	0006952	biological_process	defense response
C	0008233	molecular_function	peptidase activity
C	0008234	molecular_function	cysteine-type peptidase activity
C	0009506	cellular_component	plasmodesma
C	0016540	biological_process	protein autoprocessing
C	0016787	molecular_function	hydrolase activity
C	0042802	molecular_function	identical protein binding
C	0043068	biological_process	positive regulation of programmed cell death
D	0004197	molecular_function	cysteine-type endopeptidase activity
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006508	biological_process	proteolysis
D	0006952	biological_process	defense response
D	0008233	molecular_function	peptidase activity
D	0008234	molecular_function	cysteine-type peptidase activity
D	0009506	cellular_component	plasmodesma
D	0016540	biological_process	protein autoprocessing
D	0016787	molecular_function	hydrolase activity
D	0042802	molecular_function	identical protein binding
D	0043068	biological_process	positive regulation of programmed cell death

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SO4 A 501

Chain	Residue
A	GLU18
A	ARG20
A	LYS210
A	LYS223
D	PRO359

---

site_id	AC2
Number of Residues	1
Details	binding site for residue SO4 A 502

Chain	Residue
A	ARG63

---

site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 503

Chain	Residue
A	VAL419
A	LYS3
A	ARG131
A	CYS418

---

site_id	AC4
Number of Residues	1
Details	binding site for residue SO4 B 501

Chain	Residue
B	ASN61

---

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 C 501

Chain	Residue
B	GLY14
C	ARG20
C	HIS221

---

site_id	AC6
Number of Residues	1
Details	binding site for residue SO4 C 502

Chain	Residue
C	GLN56

---

site_id	AC7
Number of Residues	2
Details	binding site for residue SO4 C 503

Chain	Residue
C	PRO228
C	LEU229

---

site_id	AC8
Number of Residues	3
Details	binding site for residue SO4 D 501

Chain	Residue
D	LYS3
D	ARG131
D	VAL419

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Site: {"description":"Cleavage; by autolysis"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"UniProtKB","id":"Q9FYE1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---