Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004470 | molecular_function | malic enzyme activity |
A | 0004471 | molecular_function | malate dehydrogenase (decarboxylating) (NAD+) activity |
A | 0005739 | cellular_component | mitochondrion |
A | 0006090 | biological_process | pyruvate metabolic process |
A | 0006108 | biological_process | malate metabolic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
A | 0046872 | molecular_function | metal ion binding |
A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | binding site for residue EPE A 601 |
Chain | Residue |
A | GLU144 |
A | GLY180 |
A | ILE181 |
A | ASP182 |
A | GLY448 |
A | LYS449 |
A | THR450 |
A | LEU471 |
A | ALA550 |
site_id | AC2 |
Number of Residues | 20 |
Details | binding site for residue SZG A 602 |
Chain | Residue |
A | LEU17 |
A | THR18 |
A | ASN23 |
A | GLY25 |
A | THR26 |
A | ARG41 |
A | GLN52 |
A | ARG55 |
A | GLN59 |
A | HIS72 |
A | SER75 |
A | VAL76 |
A | ASN80 |
A | LEU83 |
A | HIS113 |
A | PHE116 |
A | ARG117 |
A | GLU118 |
A | ARG119 |
A | TYR122 |
Functional Information from PROSITE/UniProt
site_id | PS00331 |
Number of Residues | 17 |
Details | MALIC_ENZYMES Malic enzymes signature. FnDDiqGTGaViAAGFL |
Chain | Residue | Details |
A | PHE263-LEU279 | |