6W35

A new Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0004622	molecular_function	phosphatidylcholine lysophospholipase activity
A	0005044	molecular_function	scavenger receptor activity
A	0005509	molecular_function	calcium ion binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006629	biological_process	lipid metabolic process
A	0006935	biological_process	chemotaxis
A	0006955	biological_process	immune response
A	0008270	molecular_function	zinc ion binding
A	0016042	biological_process	lipid catabolic process
A	0016192	biological_process	vesicle-mediated transport
A	0016787	molecular_function	hydrolase activity
A	0030247	molecular_function	polysaccharide binding
A	0034638	biological_process	phosphatidylcholine catabolic process
A	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00524
Number of Residues	21
Details	SMB_1 Somatomedin B domain (SMB) signature. CrCdnlCksyts.CChDFdelC

Chain	Residue	Details
A	CYS74-CYS94
A	CYS118-CYS138

---