6W35
A new Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0005044 | molecular_function | scavenger receptor activity |
A | 0005576 | cellular_component | extracellular region |
A | 0006955 | biological_process | immune response |
A | 0016020 | cellular_component | membrane |
A | 0016192 | biological_process | vesicle-mediated transport |
A | 0016787 | molecular_function | hydrolase activity |
A | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
A | 0030247 | molecular_function | polysaccharide binding |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PROSITE/UniProt
site_id | PS00524 |
Number of Residues | 21 |
Details | SMB_1 Somatomedin B domain (SMB) signature. CrCdnlCksyts.CChDFdelC |
Chain | Residue | Details |
A | CYS74-CYS94 | |
A | CYS118-CYS138 |