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6W35

A new Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0005044molecular_functionscavenger receptor activity
A0005576cellular_componentextracellular region
A0006955biological_processimmune response
A0016020cellular_componentmembrane
A0016192biological_processvesicle-mediated transport
A0016787molecular_functionhydrolase activity
A0016788molecular_functionhydrolase activity, acting on ester bonds
A0030247molecular_functionpolysaccharide binding
A0046872molecular_functionmetal ion binding
Functional Information from PROSITE/UniProt
site_idPS00524
Number of Residues21
DetailsSMB_1 Somatomedin B domain (SMB) signature. CrCdnlCksyts.CChDFdelC
ChainResidueDetails
ACYS74-CYS94
ACYS118-CYS138

225946

PDB entries from 2024-10-09

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