Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0008800 | molecular_function | beta-lactamase activity |
A | 0017001 | biological_process | antibiotic catabolic process |
A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
A | 0046677 | biological_process | response to antibiotic |
B | 0008800 | molecular_function | beta-lactamase activity |
B | 0017001 | biological_process | antibiotic catabolic process |
B | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
B | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | binding site for residue NXL A 401 |
Chain | Residue |
A | ALA88 |
A | SER252 |
A | GLY253 |
A | ALA254 |
A | ARG260 |
A | HOH511 |
A | HOH548 |
A | HOH576 |
A | HOH620 |
A | SER89 |
A | LYS92 |
A | SER147 |
A | ASN149 |
A | GLU183 |
A | ASN187 |
A | THR233 |
A | LYS251 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue FMT A 402 |
Chain | Residue |
A | VAL111 |
A | HIS113 |
A | HOH533 |
A | HOH606 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue EDO B 401 |
Chain | Residue |
B | ALA62 |
B | ARG80 |
B | PHE283 |
site_id | AC4 |
Number of Residues | 19 |
Details | binding site for Di-peptide NXL B 402 and SER B 89 |
Chain | Residue |
B | TYR87 |
B | ALA88 |
B | THR90 |
B | TYR91 |
B | LYS92 |
B | TYR122 |
B | SER147 |
B | ASN149 |
B | GLU183 |
B | ASN187 |
B | THR233 |
B | LYS251 |
B | SER252 |
B | GLY253 |
B | ALA254 |
B | ARG260 |
B | HOH532 |
B | HOH551 |
B | HOH575 |
Functional Information from PROSITE/UniProt
site_id | PS00146 |
Number of Residues | 16 |
Details | BETA_LACTAMASE_A Beta-lactamase class-A active site. FaYASTyKvlaAAAVL |
Chain | Residue | Details |
A | PHE85-LEU100 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | SER89 | |
B | SER89 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | LYS251 | |
B | LYS251 | |