Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6W18

Structure of S. pombe Arp2/3 complex in inactive state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005200	molecular_function	structural constituent of cytoskeleton
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005885	cellular_component	Arp2/3 protein complex
A	0015629	cellular_component	actin cytoskeleton
A	0030041	biological_process	actin filament polymerization
A	0030479	cellular_component	actin cortical patch
A	0032153	cellular_component	cell division site
A	0034314	biological_process	Arp2/3 complex-mediated actin nucleation
A	0044396	biological_process	actin cortical patch organization
A	0045324	biological_process	late endosome to vacuole transport
A	0051015	molecular_function	actin filament binding
A	0051285	cellular_component	cell cortex of cell tip
A	0072583	biological_process	clathrin-dependent endocytosis
A	0090135	biological_process	actin filament branching
B	0005200	molecular_function	structural constituent of cytoskeleton
B	0005524	molecular_function	ATP binding
B	0005885	cellular_component	Arp2/3 protein complex
B	0005938	cellular_component	cell cortex
B	0015629	cellular_component	actin cytoskeleton
B	0030479	cellular_component	actin cortical patch
B	0031097	cellular_component	medial cortex
B	0034314	biological_process	Arp2/3 complex-mediated actin nucleation
B	0045324	biological_process	late endosome to vacuole transport
B	0051015	molecular_function	actin filament binding
B	0051285	cellular_component	cell cortex of cell tip
B	0072583	biological_process	clathrin-dependent endocytosis
B	0090135	biological_process	actin filament branching
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005885	cellular_component	Arp2/3 protein complex
C	0015629	cellular_component	actin cytoskeleton
C	0030036	biological_process	actin cytoskeleton organization
C	0030479	cellular_component	actin cortical patch
C	0030866	biological_process	cortical actin cytoskeleton organization
C	0032153	cellular_component	cell division site
C	0034314	biological_process	Arp2/3 complex-mediated actin nucleation
C	0051015	molecular_function	actin filament binding
C	0051286	cellular_component	cell tip
C	0072583	biological_process	clathrin-dependent endocytosis
C	0090135	biological_process	actin filament branching
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005885	cellular_component	Arp2/3 protein complex
D	0015629	cellular_component	actin cytoskeleton
D	0030041	biological_process	actin filament polymerization
D	0030479	cellular_component	actin cortical patch
D	0032153	cellular_component	cell division site
D	0034314	biological_process	Arp2/3 complex-mediated actin nucleation
D	0044396	biological_process	actin cortical patch organization
D	0051015	molecular_function	actin filament binding
D	0051286	cellular_component	cell tip
D	0060090	molecular_function	molecular adaptor activity
D	0072583	biological_process	clathrin-dependent endocytosis
D	0090135	biological_process	actin filament branching
D	0140378	molecular_function	protein complex scaffold activity
E	0000147	biological_process	actin cortical patch assembly
E	0005634	cellular_component	nucleus
E	0005826	cellular_component	actomyosin contractile ring
E	0005829	cellular_component	cytosol
E	0005856	cellular_component	cytoskeleton
E	0005885	cellular_component	Arp2/3 protein complex
E	0007163	biological_process	establishment or maintenance of cell polarity
E	0015629	cellular_component	actin cytoskeleton
E	0030479	cellular_component	actin cortical patch
E	0032153	cellular_component	cell division site
E	0032432	cellular_component	actin filament bundle
E	0034314	biological_process	Arp2/3 complex-mediated actin nucleation
E	0051015	molecular_function	actin filament binding
E	0051286	cellular_component	cell tip
E	0072583	biological_process	clathrin-dependent endocytosis
E	0090135	biological_process	actin filament branching
F	0005634	cellular_component	nucleus
F	0005829	cellular_component	cytosol
F	0005885	cellular_component	Arp2/3 protein complex
F	0015629	cellular_component	actin cytoskeleton
F	0030041	biological_process	actin filament polymerization
F	0030479	cellular_component	actin cortical patch
F	0034314	biological_process	Arp2/3 complex-mediated actin nucleation
F	0051015	molecular_function	actin filament binding
F	0072583	biological_process	clathrin-dependent endocytosis
F	0090135	biological_process	actin filament branching
F	0140378	molecular_function	protein complex scaffold activity
G	0005634	cellular_component	nucleus
G	0005768	cellular_component	endosome
G	0005829	cellular_component	cytosol
G	0005885	cellular_component	Arp2/3 protein complex
G	0015629	cellular_component	actin cytoskeleton
G	0030479	cellular_component	actin cortical patch
G	0030674	molecular_function	protein-macromolecule adaptor activity
G	0030833	biological_process	regulation of actin filament polymerization
G	0030863	cellular_component	cortical cytoskeleton
G	0034314	biological_process	Arp2/3 complex-mediated actin nucleation
G	0043332	cellular_component	mating projection tip
G	0044396	biological_process	actin cortical patch organization
G	0051015	molecular_function	actin filament binding
G	0072583	biological_process	clathrin-dependent endocytosis
G	0090135	biological_process	actin filament branching

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue ATP A 501

Chain	Residue
A	THR14
A	GLY335
A	SER336
A	LEU338
A	PHE339
A	MG502

site_id	AC2
Number of Residues	1
Details	binding site for residue MG A 502

Chain	Residue
A	ATP501

site_id	AC3
Number of Residues	7
Details	binding site for residue ATP B 401

Chain	Residue
B	GLY156
B	ASP157
B	GLY182
B	GLU214
B	MET305
B	GLY11
B	THR12

Functional Information from PROSITE/UniProt

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEPpMNPvaNR

Chain	Residue	Details
B	LEU104-ARG116
A	LEU127-ARG139

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	39
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	39
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	41
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	39
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	39
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	34
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)