6W0U

HIV Integrase core domain in complex with inhibitor 2-(2-ethynyl-5-methyl-1-benzofuran-3-yl)acetic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0015074	biological_process	DNA integration

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue S0Y A 301

Chain	Residue
A	GLN95
A	MET178
A	TYR99
A	LEU102
A	THR125
A	ALA129
A	ALA169
A	GLU170
A	HIS171
A	THR174

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site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 302

Chain	Residue
A	THR66
A	HIS67
A	ASN155
A	LYS159
A	TYR194

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site_id	AC3
Number of Residues	1
Details	binding site for residue IOD A 303

Chain	Residue
A	GLN137

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site_id	AC4
Number of Residues	2
Details	binding site for residue IOD A 304

Chain	Residue
A	HIS67
A	GLY70

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site_id	AC5
Number of Residues	2
Details	binding site for residue IOD A 305

Chain	Residue
A	LYS173
A	HOH426

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site_id	AC6
Number of Residues	3
Details	binding site for residue IOD A 306

Chain	Residue
A	SER123
A	THR124
A	THR125

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site_id	AC7
Number of Residues	1
Details	binding site for residue IOD A 307

Chain	Residue
A	PRO142

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING:

Chain	Residue	Details
A	ASP64
A	ASP116

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P04585

Chain	Residue	Details
A	GLU152

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